› In studies, people with RA (rheumatoid arthritis) taking methotrexate had improved symptoms when Cimzia (Certolizumab) was added to methotrexate.
› Cimzia (Certolizumab) is as effective as other similar medicines for Crohn's disease. It can be an option for people taking other RA medications that have too many side effects of don't work anymore.
› Cimzia (Certolizumab) lasts longer in the body than other RA medications, letting it work longer.
› Available in a prefilled syringe. This can make it easier to give yourself the injection.
› Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
› You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
› Humira (adalimumab) treats many different autoimmune conditions.
› Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
Downsides and risks
› Can lower your immune system's ability to fight infections. You can get serious infections such as TB (tuberculosis) and infections caused by viruses, fungi, or bacteria.
› Can have a higher risk for causing bladder infections, rash, and upper respiratory infections (cold or flu) compared to other similar medicines.
› Cimzia (Certolizumab) can increase the risk of lymphoma, leukemia, and other cancers.
› Requires routine tests to check for infections.
› Not a good choice if you have a history of heart failure, nervous system problems, or hepatitis B.
› There's no generic available and it can be very expensive.
› Not first-choice treatment for rheumatoid arthritis.
› Humira (adalimumab) is an injection and not an oral medication.
› Humira (adalimumab) is expensive because there's no generic available yet.
› Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
› You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
› Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
Tips from our pharmacists for people taking the medication
› Cimzia (Certolizumab) is a medicine that's injected just under the skin (subcutaneous). It can be given in your doctor's office or you can do it yourself at home.
› It can take multiple doses before you start to see any effects, so don't change your dose without talking to your doctor.
› Tell your doctor if you have night sweats, persistent fever, fatigue, weight loss, or swollen lymph nodes.
› You'll need to have a TB (tuberculosis) test before you start Cimzia (Certolizumab) and periodically during treatment.
› Don't get any live vaccines while you're taking Cimzia (Certolizumab) since they may not work as well. Wait at least 3 months after you've stopped taking Cimzia (Certolizumab) before getting a live vaccine.
› Humira (adalimumab) is a medication that's injected under the skin. Your doctor can give you your first dose, then you can inject yourself at home once you feel comfortable doing so on your own.
› Humira (adalimumab) lowers your ability to fight infections, so it's important to let your doctor know if you have a fever, cough, or flu-like symptoms.
› Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
› Each time you use Humira (adalimumab), it's important to rotate the sites you chose to inject it in. Don't inject Humira (adalimumab) into skin that's red, bruised, or irritated.
› As with all injection medicines, store securely away from children and throw away used syringes in an FDA-approved sharps disposal container, and not in the trash.