Compare Cimzia vs. Remicade

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cimzia
(certolizumab)

Remicade
(infliximab)

Calms the immune system and prevents joint damage. Cimzia (certolizumab) effectively calms down your immune system, but you have to be comfortable receiving injections.Calms down your immune system. Remicade (infliximab) is an effective treatment for many autoimmune diseases, but you can have serious side effects.
Reviews & ratings
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Have you used Cimzia (certolizumab)?
Worth itNot sureNot worth it
Reviews for Remicade
76%
-9% worse vs. Cimzia
62%
-4% worse vs. Cimzia
15%
+15% better vs. Cimzia
Have you used Remicade (infliximab)?
Worth itNot sureNot worth it
Side effects
CimziaRemicade
  • Joint pain 2%
  • Urinary tract infections 1%
  • Upper airway infections 7%
  • Infections 8%
  • Fever 1%
  • Sore throat 2%
  • Rash 2%
  • Acute bronchitis 2%
  • Fatigue 1%
  • Back pain 3%
More Cimzia side effects »
  • Yeast infectionn 2%
  • Itchiness 5%
  • Fever 3%
  • High blood pressure 2%
  • Pain 1%
  • Joint pain 1%
  • Urinary tract infection 2%
  • Fatigue 2%
  • Indigestion 3%
  • Bronchitis 1%
More Remicade side effects »
How it works
CimziaRemicade
Cimzia (certolizumab) blocks a protein called TNF (tumor necrosis factor) that causes inflammation.Remicade (infliximab) blocks a protein in your immune system called TNF (tumor necrosis factor) that causes inflammation.
Type of medication
CimziaRemicade
Prescription onlyNo lower cost generic availablePrescription onlyNo lower cost generic available
Available as
CimziaRemicade
  • Injection
  • Injection
Used for
CimziaRemicade
Risk factors for serious side effects
CimziaRemicade
  • Taking other immunosuppressant medications such as methotrexate or steroids
  • Age 65 or older
  • Active, chronic, or recurrent infection
  • Comorbidities
  • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Cimzia (certolizumab)
Detailed Cimzia (certolizumab) risks & warnings »
  • Taking other immunosuppressant drugs
  • Age 65 or older
  • Comorbidities
  • History of malignancy
Detailed Remicade (infliximab) risks & warnings »
Pregnancy
Weight
CimziaRemicade
No weight related info.
  • Although rare, Remicade (infliximab) can hurt your liver. If you have appetite/weight loss, stomach discomfort, vomiting, or dark urine, talk to your doctor. If you have yellowing of skin/eyes, talk to your doctor right away.
Upsides and benefits
CimziaRemicade
  • People taking Cimzia (certolizumab) for Crohn's disease, rheumatoid arthritis and other autoimmune conditions had greater clinical response compared to people who did not take Cimzia (certolizumab).
  • Compared to some other drugs used to treat autoimmune conditions, Cimzia (certolizumab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
  • You can give yourself Cimzia (certolizumab) on your own at home rather than visiting a clinic or hospital.
  • After the initial dosing, you need to take Cimzia (certolizumab) every 4 weeks.
  • Cimzia (certolizumab) has been on the market for almost 10 years.
  • People taking Remicade (infliximab) for ulcerative colitis, Crohn's disease, rheumatoid arthritis and other autoimmune conditions had more clinical response, clinical remission and symptom improvement compared to people who did not take Remicade (infliximab).
  • People who were also taking steroids for treatment were able to discontinue steroid use while taking Remicade (infliximab).
  • Remicade (infliximab) has almost two decades of clinical trial data and real-life experience with many people who have used it.
  • After the initial dosing, you only need to take Remicade (infliximab) every 6-8 weeks, depending on your condition.
  • Compared to other medications used to treat autoimmune conditions, Remicade (infliximab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
Downsides and risks
CimziaRemicade
  • Cimzia (certolizumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, or had tuberculosis (TB) in the past.
  • Can in some cases cause bladder infections, rash and respiratory infections (cold or flu)
  • In rare cases, Cimzia (certolizumab) has been associated with cancers in children and adolescents.
  • Can increase your risk of side effects if you have a history of heart failure, nervous system conditions, or hepatitis B.
  • There's no generic available and it can be expensive.
  • You have to receive this medication at your doctor's office or clinic. You might need to be tested regularly for tuberculosis.
  • Remicade (infliximab) lowers your ability to fight infection and can cause serious illness. The risk is greater if you take other drugs that lower your immune system, or have a history of diabetes or tuberculosis.
  • Remicade (infliximab) can in some cases worsen symptoms of heart failure or neurologic conditions. People 65 years and older may have more side effects from this medication.
  • In rare cases, Remicade (infliximab) has been associated with cancers in children and adolescents.
  • No generic available, so it can be costly.
Tips from our pharmacists for people taking the medication
CimziaRemicade
  • Cimzia (certolizumab) is a medication that's injected under the skin. Your doctor can give you your first dose, then you can inject yourself at home once you feel comfortable doing so.
  • Each time you use Cimzia (certolizumab), it's important to rotate the sites you chose to inject it in. Don't inject Cimzia (certolizumab) into skin that's red, bruised, or irritated.
  • Keep Cimzia (certolizumab) refrigerated, but let it rest at room temperature for 30 to 60 minutes before using it.
  • Cimzia (certolizumab) lowers your ability to fight infections, so it's important to let your doctor know if you have a fever, cough, or flu-like symptoms.
  • If you have any signs or new or worsening symptoms such as heart, neurological, or autoimmune conditions, talk to your doctor. Tell your doctor about symptoms such as bruising or bleeding.
  • As with all injection medicines, store securely away from children and throw away used syringes in an FDA-approved sharps disposal container and not in the trash.
  • Remicade (infliximab) can in some cases cause a serious allergic reaction either immediately or several days after the treatment. Your doctor can give you medicines that will lower this risk.
  • Your doctor will test you for tuberculosis before taking Remicade (infliximab) and regularly during treatment.
  • Remicade (infliximab) lowers your immune system's ability to fight infections, so it's important to let your doctor know if you notice a fever, cough, or flu-like symptoms.
  • You should not receive any live vaccines while taking Remicade (infliximab). Tell your doctor that you are taking Remicade (infliximab) before receiving any vaccines.
  • If you have any signs or new or worsening symptoms such as heart, neurological, or autoimmune conditions, talk to your doctor. Tell your doctor about symptoms such as bruising or bleeding.
Learn more
More about CimziaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Cimzia (certolizumab)?
Worth itNot sureNot worth it
More about RemicadeSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Remicade (infliximab)?
Worth itNot sureNot worth it