Compare Cipro vs. Cleocin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cipro
(Ciprofloxacin)

Cleocin T
(Clindamycin Phosphate)

Kills bacteria. Cipro (Ciprofloxacin) is a good and cheap antibiotic to treat many types of bacterial infections. However, you have to reduce your caffeine intake, and have to protect yourself from the sun.Topical treatment for acne. Cleocin T (Clindamycin Phosphate) is good for treating many bacterial infections and is available as a generic. If you're taking the vaginal form, you have to avoid sex and tampons for the period your doctor tells you to. The topical form can cause skin sensitivity and irritation.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.180965147453083Cipro
Reviews for Cipro (Ciprofloxacin)
64%
of people say Cipro (Ciprofloxacin) is worth it
53%
say it works well
17%
say it's a big hassle
Reviews for Cleocin T (Clindamycin Phosphate)
57%
7% vs. Cipro (Ciprofloxacin)
43%
10% vs. Cipro (Ciprofloxacin)
20%
3% vs. Cipro (Ciprofloxacin)
Side effects
CiproCleocin

The Cipro FDA package insert doesn’t have numbers about how common side effects are.

More about Cipro side effects »
  • Vaginal moniliasis 6%
More Cleocin side effects »
How it works
CiproCleocin
Cipro (Ciprofloxacin) is an antibiotic. It kills bacteria by preventing them from reproducing and repairing themselves.Cleocin T (Clindamycin Phosphate) is an antibiotic and acne medicine. It kills bacteria by preventing them from reproducing and repairing themselves.
Type of medication
CiproCleocin
Antibiotic
Fluoroquinolone
Prescription only
Acne agent
Antibiotic
Prescription only
Available as
CiproCleocin
  • Pill
  • Extended release
  • Infusion (IV)
  • Topical
  • Cream, gel, or ointment
  • Foam
  • Vaginal cream
  • Vaginal suppository
  • Injection
Used for (click to learn more)
CiproCleocin
Risk factors for serious side effects
CiproCleocin
  • Over 60 years of age
  • On long-term steroid use
  • Heart, kidney, or lung transplant
  • Myasthenia gravis
        Detailed Cipro (Ciprofloxacin) risks & warnings »
          • History of liver disease
            Detailed Cleocin T (Clindamycin Phosphate) risks & warnings »
            Pregnancy category
            CiproCleocin
            CFDA pregnancy category (Weigh risks vs. benefits)

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            See the FDA package insert
            BFDA pregnancy category (Probably safe)

            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

            See the FDA package insert
            Alcohol
            No specific alcohol-related info.No specific alcohol-related info.
            Food
            No specific food-related info.
            • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
            • Can be taken with or without food.
            Kidneys and liver
            No specific kidneys and liver-related info.No specific kidneys and liver-related info.
            Sex
            No specific sex-related info.
            • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
            • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
            Sleep
            No specific sleep-related info.No specific sleep-related info.
            Weight
            No specific weight-related info.No specific weight-related info.
            Upsides and benefits
            CiproCleocin
            • Available in different forms: tablet, capsule, and suspension.
            • Available in generic.
            • Used to treat many types of bacterial infections.
            • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
            • Topical form treats acne.
            • Available in different oral forms: tablet, capsule, and suspension.
            • Available in forms to treat skin infections and vaginal infections.
            • Can be taken with or without food.
            • Available in generic.
            • Used to treat many types of bacterial infections.
            • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
            Downsides and risks
            CiproCleocin
            • Must be used with caution in people over 60 years of age, or who have had either an organ transplant or on long-term steroid use due to possible tendon rupture.
            • If you have caffeine while on Ciprofloxacin, you may noticed increased effects of the caffeine.
            • Ciprofloxacin can make your skin more sensitive to the sun.
            • Can't be used if you've ever had myasthenia gravis.
            • Can cause diarrhea.
            • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
            • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
            • If you're allergic to aspirin, your doctor may have to prescribe an alternate.
            • If you have to take live vaccines, talk to your doctor when to take them since Clindamycin can make it less effective.
            • If you're taking the topical form, it can cause sensitivity and irritation.
            Tips from our pharmacists for people taking the medication
            CiproCleocin
            • If you notice pain in your Achilles tendons, contact your doctor.
            • Wear sunscreen if you're going to be out in the sun.
            • Take the medication exactly how the doctor tells you to.
            • Avoid taking this by itself with dairy products (milk, cheese, yogurt) or with juice with calcium.
            • Take this medication at least 2 hours before or 6 hours after any antacids with magnesium or aluminum or with any vitamins with calcium, iron or zinc.
            • Can cause diarrhea, nausea or vomiting.
            • Limit your caffeine intake while taking this medication.
            • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
            • Take this medication exactly how your doctor tells you to.
            • Store the suspension at room temperature.
            • If you're using the topical form, it can take a few weeks to see the full effect.
            • Keep the topical form out of your eyes, nose and mouth.
            • If you're using the topical form, Don't put makeup or bandages over it.
            • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
            Learn more
            More about CiproSide effectsReviews & ratingsAlternativesFDA package insert
            More about CleocinSide effectsReviews & ratingsAlternativesFDA package insert