Compare Cipro vs. doxycycline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cipro (ciprofloxacin)

Prescription only

Vibramycin (doxycycline)

Prescription only
Treats bacterial infections.

Cipro (ciprofloxacin) is a good, cheap antibiotic that treats many types of bacterial infections, but it interacts with some food and drugs.

5.2/ 7 average rating with 755 reviewsforCipro
Treats bacterial infections.

Vibramycin (doxycycline) is good for treating many bacterial infections, but can increase your skin's sensitivity to sunlight and make you more likely to get a sunburn or rash.

4.3/ 7 average rating with 112 reviewsfordoxycycline
Upsides
  • Cipro (ciprofloxacin) is available in generic.
  • Cipro (ciprofloxacin) comes in different forms, including intravenous (IV) injection.
  • Vibramycin (doxycycline) is a good alternative for some types of bacterial infections for people who are allergic to penicillin.
  • Available in generic.
  • Available as a liquid for those who have trouble swallowing.
  • Vibramycin (doxycycline) is safe for people age 65 or older and those who have kidney problems.
Downsides
  • Cipro (ciprofloxacin) should be used with caution if you have kidney problems.
  • If you drink caffeine while on Cipro (ciprofloxacin), you may notice increased effects of the caffeine.
  • Some bacteria have developed resistance to Cipro (ciprofloxacin).
  • Cipro (ciprofloxacin) can interact with many other medications. Tell your doctor and pharmacist what medications, over-the-counter products, and supplements you are taking before starting Cipro (ciprofloxacin).
  • Vibramycin (doxycycline) makes your skin more sensitive to the sun.
  • Vibramycin (doxycycline) can make some birth control less effective, so you may have to use barrier methods (like condoms) while on it.
  • Vitamins, iron supplements, or antacids can't be taken at the same time as Vibramycin (doxycycline).
  • Vibramycin (doxycycline) can cause severe diarrhea that is usually watery and bloody, as late as up to 2 months after finishing the medicine.
Used for
Dosage forms
  • Pill
  • Liquid
  • Injection
  • Extended release pill
  • Pill
  • Delayed release pill
  • Liquid
Price
No pricing information available
Lowest price near you
$36.81
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Reviews
755 
63%
think this treatment is worth it
53%
think this treatment works well
17%
think this treatment is a hassle

Have you used Cipro (ciprofloxacin)?

Leave a review
112 
49%
think this treatment is worth it
36%
think this treatment works well
24%
think this treatment is a hassle

Have you used Vibramycin (doxycycline)?

Leave a review
Side effects
2possible side effects
  • Nausea
    3%
  • Diarrhea
    2%
See more detailed side effects
The Vibramycin (doxycycline) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Tendon rupture

    People over age 60

    ...and 2 more risk factors

  • Myasthenia gravis

    Myasthenia gravis

  • Central nervous system effects

    Central nervous system disorders

    ...and 1 more risk factors

  • Heart rhythm problems

    Use with other QT prolonging drugs

    ...and 1 more risk factors

See more detailed risks and warnings
  • Color changes in teeth of young children and unborn babies

    Age 8 or younger

    ...and 2 more risk factors

  • Severe diarrhea

    Using Vibramycin (doxycycline) for a long period of time

  • Sunburn or rash

    Being in the sun for a long period of time

    ...and 1 more risk factors

  • Harm to fetus (unborn baby)

    Women who can potentially or want to become pregnant

    ...and 1 more risk factors

See more detailed risks and warnings