Treats allergy symptoms. Clarinex (Desloratadine) is a good option for once-daily allergy relief. It doesn't make you feel sleepy, but you need a prescription. Treats allergy symptoms. Zyrtec (Cetirizine) is a once-daily allergy relief medication that won't make you feel too sleepy. How it works Clarinex (Desloratadine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. Zyrtec (Cetirizine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. Antihistamines can also make you sleepy, but Zyrtec is a low-drowsiness version. Type of medication Antihistamine
› 2nd generation
Prescription only Antihistamine
› 2nd generation
Prescription or OTC Available as Pill Dissolving tablet Liquid Pill Liquid capsule Dissolving tablet Liquid Used for (click to learn more) Find lowest prices Save on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance. Reviews & ratings Everyone Men Women Button Group. All currently active Everyone Men Women All ages 18-34 35-54 55+ Button Group. All currently active All ages 18-34 35-54 55+
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Reviews for Zyrtec (Cetirizine)
vs. Clarinex (Desloratadine)
34% vs. Clarinex (Desloratadine)
+13% vs. Clarinex (Desloratadine)
Ear, nose, or throat infection 8%
Middle ear inflammation 4%
Sore throat 3%
Loss of appetite 3%
Runny nose 2%
More Clarinex side effects »
We haven’t found good data for Zyrtec side effects.
FDA side effect reports for Zyrtec » Risk factors for serious side effects Coming soon. › Taking with alcohol › Taking other medicines that make you less alert › Current kidney disease › Current liver disease Detailed Zyrtec (Cetirizine) risks & warnings » Pregnancy category
Alcohol No specific alcohol-related info. No specific alcohol-related info.
Food No specific food-related info. No specific food-related info.
Kidneys and liver No specific kidneys and liver-related info. › People with kidney or liver disease may need to take a lower dose of Zyrtec (Cetirizine) to prevent overdose. Talk with your doctor to be sure you are using the correct dose.
Sex No specific sex-related info. No specific sex-related info.
Sleep No specific sleep-related info. No specific sleep-related info.
Weight No specific weight-related info. No specific weight-related info. Upsides and benefits › Relieves allergy symptoms like sneezing, runny nose, congestion, hives, or itchy skin. › Preferred for older people since it causes little to no drowsiness compared to other antihistamines like Diphenhydramine (Benadryl). › Works faster than other non-drowsy antihistamines like Loratadine (Claritin). › Side effects are rare and usually mild. › Available as a liquid or fast-dissolving tablet for people who don't like swallowing pills. › Zyrtec (Cetirizine) works as well as other antihistamines to treat sneezing and runny nose, but causes less sedation. › Works well to also treat hives and itchy skin. › Zyrtec (Cetirizine) is available over the counter without a prescription. › It comes as a tablet, liquid, and quick-dissolving tablet. › It can provide quick relief of allergy symptoms for both kids and adults. › It's okay to take with most other medications because it has few drug interactions. › Most people don't get any side effects from Zyrtec (Cetirizine). Downsides and risks › May not work as fast as the other antihistamines that make you sleepy (like Benadryl). › Not a good medication for pregnant women to take. › Although it works fast, its effectiveness wears off for some people over time. › Zyrtec (Cetirizine) can be slightly more sedating than Allegra or Claritin. › Some people find that other more sedating antihistamines, like Benadryl, are more effective for them than Zyrtec (Cetirizine). › If you have daily allergy symptoms, a prescription nasal steroid spray might be better for you long-term. Tips from our pharmacists for people taking the medication › Starts working in an hour. › Take it once a day when needed. › Works the best if used regularly during allergy season. › Can give you a headache or diarrhea, but it rarely causes drowsiness or dizziness. › Starts working in a few hours. Only take it once a day. › Can make you feel sleepy, so take it at bedtime if needed. › Avoid some of the side effects by drinking plenty of non-caffeinated liquids. › If you need to use it for more than a few weeks, talk with your doctor about trying a nasal steroid instead since it might work better for you long-term. › Using an antihistamine eye drop instead can also work better to treat itchy or watery eyes. Learn more More about Clarinex Side effects Reviews & ratings Alternatives FDA package insert More about Zyrtec Side effects Reviews & ratings Alternatives FDA package insert