Compare Claritin-D vs. Advil Allergy And Congestion Relief

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Claritin-D (loratadine / pseudoephedrine)

Prescription or OTC
Treats allergies and clears up nasal congestion.

Claritin-D (loratadine / pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness but it can keep you up at night.

5.0/ 7 average rating with 1527 reviewsforClaritin-D
Relieves cold and allergy symptoms.

Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is an okay combination medicine to relieve pain and congestion. The antihistamine can make you sleepy and the decongestant can keep you awake, so it could affect you either way.

4.9/ 7 average rating with 1437 reviewsforAdvil Allergy And Congestion Relief
Upsides
  • This once-daily, single-pill combination conveniently treats congestion and other allergy symptoms.
  • It doesn't cause any daytime drowsiness unlike other antihistamines.
  • It doesn't require a prescription from your doctor.
  • Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
Downsides
  • The decongestant (pseudoephedrine) can make you anxious or your heart race. You may not sleep as well at night.
  • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
  • It may interfere with how your other medicines work. Talk to your doctor or pharmacist before combining with other medicines.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
Used for
Dosage forms
  • Extended-release pill
  • Pill
No pricing information available
No pricing information available
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
1527 
69%
think this treatment is worth it
39%
think this treatment works well
8%
think this treatment is a hassle

Have you used Claritin-D (loratadine / pseudoephedrine)?

Leave a review
1437 
73%
think this treatment is worth it
30%
think this treatment works well
6%
think this treatment is a hassle

Have you used Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)?

Leave a review
Side effects
10possible side effects
  • Headache
    19%
  • Insomnia
    16%
  • Dry mouth
    14%
  • Drowin
    7%
  • Nervousness or anxiety
    5%
  • Dizziness
    4%
  • Indigestion
    3%
  • Nausea
    3%
  • Sore throat
    3%
  • Fatigue
    3%
See more detailed side effects
The Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • High blood pressure

    History of high blood pressure

    ...and 1 more risk factors

  • Restlesness

    History of heart problems

    ...and 3 more risk factors

  • Difficulty concentrating

    Taking with alcohol

    ...and 1 more risk factors

See more detailed risks and warnings
  • Stomach bleeding

    History of stomach bleeding or ulcers

    ...and 3 more risk factors

  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Harm to fetus

    Women of childbearing age

  • Lower kidney function

    Kidney disease

    ...and 4 more risk factors

  • High blood pressure

    History of high blood pressure

  • Heart attack or stroke

    History of heart problems

    ...and 2 more risk factors

See more detailed risks and warnings