Compare Claritin D vs. Allegra D

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Claritin D
(loratadine / pseudoephedrine)

Allegra D
(pseudoephedrine / fexofenadine)

Relieves congestion and allergy symptoms. Claritin D (Loratadine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness. It can keep you up at night if you take it too close to bedtime.Treats allergy symptoms and congestion. Allegra D (Pseudoephedrine / Fexofenadine) is a combination allergy medicine that's useful if you have congestion and runny nose.
Reviews & ratings
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Filter group. All currently selected
4.97Claritin D
Reviews for Claritin D
69%
of people (All ages) say Claritin D is worth it
39%
say it works well
8%
say it's a big hassle
1527 reviews
Have you used Claritin D (loratadine / pseudoephedrine)?
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Have you used Allegra D (pseudoephedrine / fexofenadine)?
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Side effects
Claritin DAllegra D

We haven’t found good data for Claritin D side effects.

FDA side effect reports for Claritin D »
  • Headache 3%
  • Back Pain 2%
  • Insomnia 13%
  • Nausea 7%
  • Adverse effects 4%
  • Dyspepsia 3%
  • Dry Mouth 3%
  • Dizziness 2%
  • Agitation 2%
More Allegra D side effects »
How it works
Claritin DAllegra D
Claritin D (Loratadine / Pseudoephedrine) is a combination medicine for allergies. Loratadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Allegra D (Pseudoephedrine / Fexofenadine) is a combination medicine that relieves allergy symptoms. Fexofenadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itching. Pseudoephedrine (a decongestant) clears your sinuses.
Type of medication
Claritin DAllegra D
Prescription or OTCPrescription or OTC
Available as
Claritin DAllegra D
  • Extended release
  • Extended release
Used for
Claritin DAllegra D
Risk factors for serious side effects
Claritin DAllegra D
  • History of high blood pressure
  • History of heart problems
  • Age 65 or older
  • History of seizure
  • Women of childbearing age
Detailed Claritin D (loratadine / pseudoephedrine) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • History of high blood pressure
  • History of heart problems
  • Age 65 or older
Detailed Allegra D (pseudoephedrine / fexofenadine) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
Claritin DAllegra D
  • Claritin D (Loratadine / Pseudoephedrine) contains aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, don't use this product.
No food related info.
Sleep
Claritin DAllegra D
  • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
  • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
Upsides and benefits
Claritin DAllegra D
  • The antihistamine (Loratadine) in Claritin D (Loratadine / Pseudoephedrine) works as well as other antihistamines, but causes less drowsiness. It's also less sedating than Allegra D and Zyrtec D.
  • The decongestant (Pseudoephedrine) in Claritin D (Loratadine / Pseudoephedrine) is stronger than other decongestants. It can also help relieve congestion-related headaches and ear pressure.
  • The stimulant effects of Pseudoephedrine can give you some extra energy during the day.
  • Doesn't give you rebound congestion (worse congestion symptoms after you stop taking the medicine) like decongestant nose sprays can.
  • It's available without a prescription, unlike other strong allergy medicines.
  • Available without a prescription in the drugstore.
  • It has two medications that work in different ways to help relieve nasal symptoms.
  • The antihistamine (fexofenadine) is useful for relieving itchy eyes, runny nose, or constant sneezing.
  • The decongestant (pseudoephedrine) is very good at relieving congestion.
Downsides and risks
Claritin DAllegra D
  • You can have more side effects when using combination pills than when using single-ingredient medications.
  • The decongestant (Pseudoephedrine) can make your heart race or give you anxious or restless feelings.
  • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
  • Pseudoephedrine can raise your blood pressure, so don't take it if you have high blood pressure or other heart conditions.
  • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
  • Has more side effects than Allegra since it has pseudoephedrine in it.
  • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • The decongestant (pseudoephedrine) can make your blood pressure higher and can make it harder to sleep.
  • You must show a photo ID to buy this from behind the pharmacy counter. There's a maximum limit on how much you can buy in the pharmacy at a time.
Tips from our pharmacists for people taking the medication
Claritin DAllegra D
  • Starts working in 30 minutes.
  • You need to show an ID to buy Claritin D (Loratadine / Pseudoephedrine) in the drugstore because it contains Pseudoephedrine.
  • Don't cut, crush, or chew tablets; swallow them whole.
  • It's better to take Claritin D (Loratadine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • If you need to use it for more than a few weeks, talk with your doctor since a different medication might work better for you.
  • It works best if you have nasal congestion and a runny nose.
  • Take on an empty stomach, 1 hour before eating or 2 hours after eating.
  • Shouldn't be used in kids younger than 12 years old.
  • Avoid taking it close to bedtime to prevent trouble sleeping.
  • Can cause dizziness, headache, or a fast heartbeat.
  • Talk to your doctor if you have high blood pressure or kidney problems before using it.
  • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
Learn more
More about Claritin DSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Claritin D (loratadine / pseudoephedrine)?
Worth itNot sureNot worth it
More about Allegra DSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Allegra D (pseudoephedrine / fexofenadine)?
Worth itNot sureNot worth it