Compare Claritin-D vs. Flonase

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Claritin-D (loratadine / pseudoephedrine)

Prescription or OTC

Flonase (Fluticasone)

Prescription or OTC
Treats allergies and clears up nasal congestion.

Claritin-D (loratadine / pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness but it can keep you up at night.

5.0/ 7 average rating with 1527 reviewsforClaritin-D
Relieves allergy symptoms.

Flonase (Fluticasone) is a good first-choice medicine for treating a runny or stuffy nose caused by allergies, and it's cheaper than some alternatives.

5.0/ 7 average rating with 890 reviewsforFlonase
Upsides
  • This once-daily, single-pill combination conveniently treats congestion and other allergy symptoms.
  • It doesn't cause any daytime drowsiness unlike other antihistamines.
  • It doesn't require a prescription from your doctor.
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic medication.
Downsides
  • The decongestant (pseudoephedrine) can make you anxious or your heart race. You may not sleep as well at night.
  • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
  • It may interfere with how your other medicines work. Talk to your doctor or pharmacist before combining with other medicines.
  • Flonase (Fluticasone) doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Needs to be primed (pressed/pumped until a fine spray appears) up to six times prior to using it for the first time, or if you haven't used it in 2 weeks.
  • Since the medicine in Flonase (Fluticasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
Used for
Dosage forms
  • Extended-release pill
  • Nasal spray
Price
No pricing information available
Lowest price near you
$200.08
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Reviews
1527 
69%
think this treatment is worth it
39%
think this treatment works well
8%
think this treatment is a hassle

Have you used Claritin-D (loratadine / pseudoephedrine)?

Leave a review
890 
72%
think this treatment is worth it
43%
think this treatment works well
7%
think this treatment is a hassle

Have you used Flonase (Fluticasone)?

Leave a review
Side effects
10possible side effects
  • Headache
    19%
  • Insomnia
    16%
  • Dry mouth
    14%
  • Drowin
    7%
  • Nervousness or anxiety
    5%
  • Dizziness
    4%
  • Indigestion
    3%
  • Nausea
    3%
  • Sore throat
    3%
  • Fatigue
    3%
See more detailed side effects
The Flonase (Fluticasone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • High blood pressure

    History of high blood pressure

    ...and 1 more risk factors

  • Restlesness

    History of heart problems

    ...and 3 more risk factors

  • Difficulty concentrating

    Taking with alcohol

    ...and 1 more risk factors

See more detailed risks and warnings
  • Adrenal suppression

    Switching from oral or injectable steroids to inhaled, especially if used long term

    ...and 1 more risk factors

  • Decrease in growth in children and teenagers

    Long-term use

    ...and 1 more risk factors

  • Adrenal suppression

    Switching from oral or injectable steroids to inhaled, especially if used long term

    ...and 1 more risk factors

  • Thrush in the nose and throat

    Long-term use

  • Reduced immune system

    Exposure to immunizable diseases (chickenpox and measles)

    ...and 1 more risk factors

  • Decreased wound healing

    Surgery or trauma to the nose or sinuses

  • Changes in the nasal septum

    Long-term use

See more detailed risks and warnings