Compare Claritin D vs. Sudafed

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Claritin D
(Loratadine / Pseudoephedrine)

Sudafed
(Pseudoephedrine)

Relieves congestion and allergy symptoms. Claritin D (Loratadine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness. It can keep you up at night if you take it too close to bedtime.Clears your sinuses. Sudafed (Pseudoephedrine) relieves stuffy nose, but it could keep you up at night. Don't forget your photo ID or you won't be able to buy it in the drugstore.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.9571240105540895Claritin D
Reviews for Claritin D (Loratadine / Pseudoephedrine)
69%
of people say Claritin D (Loratadine / Pseudoephedrine) is worth it
38%
say it works well
8%
say it's a big hassle
Reviews for Sudafed (Pseudoephedrine)
82%
+13% vs. Claritin D (Loratadine / Pseudoephedrine)
45%
+7% vs. Claritin D (Loratadine / Pseudoephedrine)
6%
+2% vs. Claritin D (Loratadine / Pseudoephedrine)
Side effects
Claritin DSudafed

We haven’t found good data for Claritin D side effects.

FDA side effect reports for Claritin D »

We haven’t found good data for Sudafed side effects.

FDA side effect reports for Sudafed »
How it works
Claritin DSudafed
Claritin D (Loratadine / Pseudoephedrine) is a combination medicine for allergies. Loratadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Sudafed (Pseudoephedrine) is a decongestant. It narrows blood vessels and reduces swelling in your nasal passages to make breathing easier.
Type of medication
Claritin DSudafed
Antihistamine
2nd generation
DecongestantPrescription or OTC
DecongestantPrescription or OTC
Available as
Claritin DSudafed
  • Extended release
  • Pill
  • Extended release
  • Liquid
Used for (click to learn more)
Claritin DSudafed
Risk factors for serious side effects
Claritin DSudafed
  • History of high blood pressure
  • History of heart problems
  • Age 65 or older
  • History of seizure
  • Women of childbearing age
    • Age 65 years or older
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • History of phenylketonuria (PKU)
    Detailed Claritin D (Loratadine / Pseudoephedrine) risks & warnings »
    • History of high blood pressure
    • History of heart problems
    • Age 65 years or older
    • History of seizures
    • Women of childbearing age
    Detailed Sudafed (Pseudoephedrine) risks & warnings »
    Pregnancy category
    Claritin DSudafed
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
    • The antihistamine (Loratadine) in Claritin D (Loratadine / Pseudoephedrine) works as well as other antihistamines, but causes less drowsiness. It's also less sedating than Allegra D and Zyrtec D.
    • It's better to take Claritin D (Loratadine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
    • People age 65 and older have a higher risk of troublesome side effects from taking antihistamine medications like Claritin D (Loratadine / Pseudoephedrine). Watch out for changes in vision, severe dry mouth, trouble urinating, or constipation. Also, feelings of drowsiness may leave you "unsteady" on your feet. This can make you more likely to fall causing broken bones or other serious injuries. Talk with your doctor before using Claritin D (Loratadine / Pseudoephedrine) and stop using it if you have side effects.
    • It can affect the quality of your sleep, so you can't take it too close to going to bed.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    Claritin DSudafed
    • The antihistamine (Loratadine) in Claritin D (Loratadine / Pseudoephedrine) works as well as other antihistamines, but causes less drowsiness. It's also less sedating than Allegra D and Zyrtec D.
    • The decongestant (Pseudoephedrine) in Claritin D (Loratadine / Pseudoephedrine) is stronger than other decongestants. It can also help relieve congestion-related headaches and ear pressure.
    • The stimulant effects of Pseudoephedrine can give you some extra energy during the day.
    • Doesn't give you rebound congestion (worse congestion symptoms after you stop taking the medicine) like decongestant nose sprays can.
    • It's available without a prescription, unlike other strong allergy medicines.
    • One of the best over-the-counter options to clear stuffy nose and help you breathe better.
    • Clears nasal congestion better than other decongestants like phenylephrine.
    • Can be helpful in relieving congestion-related headaches and pressure in your ears.
    • Available in regular and extended release forms.
    Downsides and risks
    Claritin DSudafed
    • You can have more side effects when using combination pills than when using single-ingredient medications.
    • The decongestant (Pseudoephedrine) can make your heart race or give you anxious or restless feelings.
    • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
    • Pseudoephedrine can raise your blood pressure, so don't take it if you have high blood pressure or other heart conditions.
    • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
    • Pseudoephedrine (a decongestant) can make your heart race or make you feel anxious and restless.
    • It can affect the quality of your sleep, so you can't take it too close to going to bed.
    • Can raise blood pressure so check with your doctor before using it if you have high blood pressure or other heart conditions.
    • Sudafed (Pseudoephedrine) isn't as effective after using it for more than 4 days straight.
    • Need to show a photo ID to buy it in the drugstore and there is a limit on how much you can buy each visit.
    Tips from our pharmacists for people taking the medication
    Claritin DSudafed
    • You need to show an ID to buy Claritin D (Loratadine / Pseudoephedrine) in the drugstore because it contains Pseudoephedrine.
    • Don't cut, crush, or chew tablets; swallow them whole.
    • It's better to take Claritin D (Loratadine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
    • If you need to use it for more than a few weeks, talk with your doctor since a different medication might work better for you.
    • Starts working in 30 minutes.
    • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
    • You need to show an ID to buy Sudafed (Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
    • Follow age-specific dosing instructions on how much to take. Don't take more than recommended on the package.
    • Don't take Sudafed (Pseudoephedrine) too close to bedtime since it can keep you awake.
    • Talk to your doctor if your symptoms don't get better in 1 week.
    • Starts working in 30 minutes.
    • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
    Learn more
    More about Claritin DSide effectsReviews & ratingsAlternativesFDA package insert
    More about SudafedSide effectsReviews & ratingsAlternativesFDA package insert