Compare Claritin vs. prednisolone acetate

Head-to-head comparisons of medication uses, side effects, ratings, and more.


(prednisolone acetate)

Treats allergy symptoms. Claritin (Loratadine) is a once-daily allergy relief medication that doesn't make you feel sleepy.Calms down redness and swelling in the eye. Omnipred (prednisolone acetate) is a steroid used in the eye that is effective for treatment and symptom relief, but with long-term use, it can have some side effects.
Reviews & ratings
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Reviews for Claritin
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1517 reviews
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Side effects
Claritinprednisolone acetate

We haven’t found good data for Claritin side effects.

FDA side effect reports for Claritin »

The prednisolone acetate FDA package insert doesn’t have numbers about how common side effects are.

More about prednisolone acetate side effects »
How it works
Claritinprednisolone acetate
Claritin (Loratadine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. Antihistamines can also make you sleepy, but Loratadine is a low-drowsiness version.Prednisolone acetate is a steroid that is similar to your body's natural steroids. It reduces swelling in the eye and alleviates pain, discomfort, or harm.
Type of medication
Claritinprednisolone acetate
Prescription or OTCPrescription only
Available as
Claritinprednisolone acetate
  • Pill
  • Chewable tablet
  • Orally disintegrating tablet
  • Liquid
  • Liquid
Used for
Claritinprednisolone acetate
  • Inflammation Of The Eye
Risk factors for serious side effects
Claritinprednisolone acetate
  • Age 65 or older
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • History of phenylketonuria (PKU)
Detailed Claritin (loratadine) risks & warnings »
  • Asthma
Detailed Omnipred (prednisolone acetate) risks & warnings »

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Claritinprednisolone acetate
  • Claritin (Loratadine) contains aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, don't use this product.
No food related info.
Claritinprednisolone acetate
No pain related info.
  • If inflammation or pain gets worse or lasts longer than 2 days while taking Omnipred (prednisolone acetate), talk to your doctor.
Claritinprednisolone acetate
  • Can make you feel sleepy, so take it at bedtime if needed.
No sleep related info.
Upsides and benefits
Claritinprednisolone acetate
  • Relieves allergy symptoms like sneezing and runny nose just as well as other antihistamines, but with less sedation (drowsiness).
  • Also treats hives and itchy skin.
  • Side effects are rare and usually mild.
  • Available over the counter without a prescription.
  • Comes as a tablet, liquid, or quick-dissolving tablet.
  • Can provide quick relief of allergy symptoms for both kids and adults.
  • Okay to take with most other medications because it doesn't have many interactions.
  • Omnipred (prednisolone acetate) works only within the eye, so it will relieve symptoms without having the side effects of oral steroids.
  • Kicks in relatively quickly to relieve symptoms.
  • Available in generic form.
Downsides and risks
Claritinprednisolone acetate
  • For some people, its effectiveness on treating allergies wears off over time.
  • Some people find that other more sedating antihistamines (like Zyrtec or Benadryl) are more effective for them.
  • If you have daily allergy symptoms, a prescription nasal steroid spray might be better for you long-term.
  • Not for kids under 2 years.
  • The Reditabs version contains aspartame (phenylalanine).
  • Depending on the condition, you might have to use Omnipred (prednisolone acetate) up to 4 times a day, particularly in the beginning.
  • If using Omnipred (prednisolone acetate) long-term, may require some monitoring by your doctor.
  • Contains sulfite, so depending on the severity of your allergy, may not be suitable for those with allergies to sulfite.
  • Long-term use can lead to increased risk of more serious side effects.
Tips from our pharmacists for people taking the medication
Claritinprednisolone acetate
  • Take it only once a day.
  • Starts working in a few hours.
  • Can make you feel sleepy, so take it at bedtime if needed.
  • Avoid possible side effects by drinking plenty of non-caffeinated liquids.
  • If you need to use it for more than a few weeks, talk with your doctor about trying a nasal steroid instead, which might work better for you long-term.
  • Using an antihistamine eye drop might work better to help itchy or watery eyes.
  • If inflammation or pain gets worse or lasts longer than 2 days while taking Omnipred (prednisolone acetate), talk to your doctor.
  • Only a small drop is needed per eye. Tilt your head back and place a drop into your lower eyelid, being careful not to touch the bottle tip to your eyelid or other surface. Afterwards, pinch the top of your nose (in between the eyes) for 15-30 seconds so that the liquid gets absorbed into your eyes.
  • If dose calls for multiple drops, wait 5 minutes in between each drop.
  • Shake well before use. You can store Omnipred (prednisolone acetate) at room temperature, but keeping it in the refrigerator can help alleviate symptoms of pain. Do not freeze.
  • Temporary burning and stinging in the eye may occur after putting in the drop.
  • If you are taking Omnipred (prednisolone acetate) long-term, you may need to gradually stop taking this medication. Take it exactly as your doctor prescribed and do not stop suddenly.
Learn more
More about ClaritinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Claritin (loratadine)?
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More about prednisolone acetateSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Omnipred (prednisolone acetate)?
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