Compare Cleocin vs. Epiduo

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cleocin T
(Clindamycin Phosphate)

Epiduo
(Adapalene / Benzoyl Peroxide)

Topical treatment for acne. Cleocin T (Clindamycin Phosphate) is good for treating many bacterial infections and is available as a generic. If you're taking the vaginal form, you have to avoid sex and tampons for the period your doctor tells you to. The topical form can cause skin sensitivity and irritation.Coming soon.
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Reviews & ratings
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4.794642857142857Cleocin
Reviews for Cleocin T (Clindamycin Phosphate)
57%
of people (All ages) say Cleocin T (Clindamycin Phosphate) is worth it
43%
say it works well
20%
say it's a big hassle
112 reviews
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Side effects
CleocinEpiduo
  • Vaginal moniliasis 6%
More Cleocin side effects »

We haven’t found good data for Epiduo side effects.

FDA side effect reports for Epiduo »
How it works
CleocinEpiduo
Cleocin T (Clindamycin Phosphate) is an antibiotic and acne medicine. It kills bacteria by preventing them from reproducing and repairing themselves.Coming soon.
Type of medication
CleocinEpiduo
Acne agent
Antibiotic
Prescription only
Coming soon.
Available as
CleocinEpiduo
  • Topical
  • Cream, gel, or ointment
  • Foam
  • Vaginal cream
  • Vaginal suppository
  • Injection
  • Cream, gel, or ointment
Used for (click to learn more)
CleocinEpiduo
  • Acne vulgaris
Risk factors for serious side effects
CleocinEpiduo
    • History of liver disease
      Detailed Cleocin T (Clindamycin Phosphate) risks & warnings »
      Coming soon.
      Pregnancy

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Food
      CleocinEpiduo
      • Can be taken with or without food.
      No food related info.
      Kidneys and liver
      CleocinEpiduo
      • There have been reports of liver damage that can require hospitalization or can cause death. These have been rare. Talk to your doctor if you notice pain in your abdomen, loss of appetite, yellowing of your skin or eyes, or dark colored urine.
      No kidneys and liver related info.
      Pain
      CleocinEpiduo
      • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
      No pain related info.
      Upsides and benefits
      CleocinEpiduo
      • Available in generic.
      • Topical form treats acne.
      • Available in different oral forms: tablet, capsule, and suspension.
      • Available in forms to treat skin infections and vaginal infections.
      • Used to treat many types of bacterial infections.
      • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
      • Can be taken with or without food.
      Coming soon
      Downsides and risks
      CleocinEpiduo
      • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
      • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
      • If you're allergic to aspirin, your doctor may have to prescribe an alternate.
      • If you have to take live vaccines, talk to your doctor when to take them since Clindamycin can make it less effective.
      • If you're taking the topical form, it can cause sensitivity and irritation.
      Coming soon
      Tips from our pharmacists for people taking the medication
      CleocinEpiduo
      • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
      • Take this medication exactly how your doctor tells you to.
      • Store the suspension at room temperature.
      • If you're using the topical form, it can take a few weeks to see the full effect.
      • Keep the topical form out of your eyes, nose and mouth.
      • If you're using the topical form, Don't put makeup or bandages over it.
      • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
      Coming soon
      Learn more
      More about CleocinSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Cleocin T (Clindamycin Phosphate)?
      Worth itNot sureNot worth it
      More about EpiduoSide effectsReviews & ratingsFDA package insert
      Have you used Epiduo (Adapalene / Benzoyl Peroxide)?
      Worth itNot sureNot worth it