Compare Cleocin vs. Epiduo

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cleocin T
(Clindamycin Phosphate)

Epiduo
(Adapalene / Benzoyl Peroxide)

Topical treatment for acne. Cleocin T (Clindamycin Phosphate) is good for treating many bacterial infections and is available as a generic. If you're taking the vaginal form, you have to avoid sex and tampons for the period your doctor tells you to. The topical form can cause skin sensitivity and irritation.Coming soon.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.794642857142857Cleocin
Reviews for Cleocin T (Clindamycin Phosphate)
57%
of people say Cleocin T (Clindamycin Phosphate) is worth it
43%
say it works well
20%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
CleocinEpiduo
  • Vaginal moniliasis 6%
More Cleocin side effects »

We haven’t found good data for Epiduo side effects.

FDA side effect reports for Epiduo »
How it works
CleocinEpiduo
Cleocin T (Clindamycin Phosphate) is an antibiotic and acne medicine. It kills bacteria by preventing them from reproducing and repairing themselves.Coming soon.
Type of medication
CleocinEpiduo
Acne agent
Antibiotic
Prescription only
Coming soon.
Available as
CleocinEpiduo
  • Topical
  • Cream, gel, or ointment
  • Foam
  • Vaginal cream
  • Vaginal suppository
  • Injection
  • Cream, gel, or ointment
Used for (click to learn more)
CleocinEpiduo
  • Acne vulgaris
Risk factors for serious side effects
CleocinEpiduo
    • History of liver disease
      Detailed Cleocin T (Clindamycin Phosphate) risks & warnings »
      Coming soon.
      Pregnancy category
      CleocinEpiduo
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.No specific alcohol-related info.
      Food
      • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
      • Can be taken with or without food.
      No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
      • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
      No specific sex-related info.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      CleocinEpiduo
      • Available in generic.
      • Topical form treats acne.
      • Available in different oral forms: tablet, capsule, and suspension.
      • Available in forms to treat skin infections and vaginal infections.
      • Used to treat many types of bacterial infections.
      • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
      • Can be taken with or without food.
      Coming soon.
      Downsides and risks
      CleocinEpiduo
      • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
      • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
      • If you're allergic to aspirin, your doctor may have to prescribe an alternate.
      • If you have to take live vaccines, talk to your doctor when to take them since Clindamycin can make it less effective.
      • If you're taking the topical form, it can cause sensitivity and irritation.
      Coming soon.
      Tips from our pharmacists for people taking the medication
      CleocinEpiduo
      • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
      • Take this medication exactly how your doctor tells you to.
      • Store the suspension at room temperature.
      • If you're using the topical form, it can take a few weeks to see the full effect.
      • Keep the topical form out of your eyes, nose and mouth.
      • If you're using the topical form, Don't put makeup or bandages over it.
      • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
      Coming soon.
      Learn more
      More about CleocinSide effectsReviews & ratingsAlternativesFDA package insert
      More about EpiduoSide effectsReviews & ratingsFDA package insert