Compare Cleocin vs. Levaquin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cleocin T
(Clindamycin Phosphate)

Levaquin
(Levofloxacin)

Topical treatment for acne. Cleocin T (Clindamycin Phosphate) is good for treating many bacterial infections and is available as a generic. If you're taking the vaginal form, you have to avoid sex and tampons for the period your doctor tells you to. The topical form can cause skin sensitivity and irritation.Kills bacteria. Levaquin (Levofloxacin) is good for treating many bacterial infections and is available as generic. However, it can cause damage to your tendons, and make your skin more sensitive to the sun.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.794642857142857Cleocin
Reviews for Cleocin T (Clindamycin Phosphate)
57%
of people say Cleocin T (Clindamycin Phosphate) is worth it
43%
say it works well
20%
say it's a big hassle
Reviews for Levaquin (Levofloxacin)
54%
3% vs. Cleocin T (Clindamycin Phosphate)
39%
4% vs. Cleocin T (Clindamycin Phosphate)
29%
9% vs. Cleocin T (Clindamycin Phosphate)
Side effects
CleocinLevaquin
  • Vaginal moniliasis 6%
More Cleocin side effects »

The Levaquin FDA package insert doesn’t have numbers about how common side effects are.

More about Levaquin side effects »
How it works
CleocinLevaquin
Cleocin T (Clindamycin Phosphate) is an antibiotic and acne medicine. It kills bacteria by preventing them from reproducing and repairing themselves.Levaquin (Levofloxacin) is an antibiotic. It kills bacteria by preventing them from reproducing and repairing themselves.
Type of medication
CleocinLevaquin
Acne agent
Antibiotic
Prescription only
Antibiotic
Fluoroquinolone
Prescription only
Available as
CleocinLevaquin
  • Topical
  • Cream, gel, or ointment
  • Foam
  • Vaginal cream
  • Vaginal suppository
  • Injection
  • Pill
  • Liquid
Used for (click to learn more)
CleocinLevaquin
Risk factors for serious side effects
CleocinLevaquin
    • History of liver disease
      Detailed Cleocin T (Clindamycin Phosphate) risks & warnings »
      • Over 60 years of age
      • On long-term steroid use
      • Heart, kidney, or lung transplant
        • History of liver disease
        • Seizures
            • Diabetes
            • Taking medications for diabetes
                Detailed Levaquin (Levofloxacin) risks & warnings »
                Pregnancy category
                CleocinLevaquin
                BFDA pregnancy category (Probably safe)

                Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                See the FDA package insert
                CFDA pregnancy category (Weigh risks vs. benefits)

                Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                See the FDA package insert
                Alcohol
                No specific alcohol-related info.No specific alcohol-related info.
                Food
                • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
                • Can be taken with or without food.
                No specific food-related info.
                Kidneys and liver
                No specific kidneys and liver-related info.No specific kidneys and liver-related info.
                Sex
                • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
                • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
                No specific sex-related info.
                Sleep
                No specific sleep-related info.No specific sleep-related info.
                Weight
                No specific weight-related info.No specific weight-related info.
                Upsides and benefits
                CleocinLevaquin
                • Topical form treats acne.
                • Available in different oral forms: tablet, capsule, and suspension.
                • Available in forms to treat skin infections and vaginal infections.
                • Can be taken with or without food.
                • Available in generic.
                • Used to treat many types of bacterial infections.
                • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
                • Available in different forms: tablet, capsule, and suspension.
                • Available in generic.
                • Used to treat many types of bacterial infections.
                • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
                Downsides and risks
                CleocinLevaquin
                • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
                • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
                • If you're allergic to aspirin, your doctor may have to prescribe an alternate.
                • If you have to take live vaccines, talk to your doctor when to take them since Clindamycin can make it less effective.
                • If you're taking the topical form, it can cause sensitivity and irritation.
                • Must be used with caution in people over 60 years of age, or who have had either an organ transplant or on long-term steroid use due to possible tendon rupture.
                • Levofloxacin can make your skin more sensitive to the sun.
                • Can't be used if you've ever had myasthenia gravis.
                • You have to space out any medications with aluminum, magnesium or zinc by at least 2 hours.
                • Can cause changes in taste, headaches, and insomnia.
                Tips from our pharmacists for people taking the medication
                CleocinLevaquin
                • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
                • Take this medication exactly how your doctor tells you to.
                • Store the suspension at room temperature.
                • If you're using the topical form, it can take a few weeks to see the full effect.
                • Keep the topical form out of your eyes, nose and mouth.
                • If you're using the topical form, Don't put makeup or bandages over it.
                • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
                • If you notice pain in your Achilles tendons, contact your doctor.
                • Wear sunscreen if you're going to be out in the sun.
                • Take the medication exactly how the doctor tells you to.
                • Take this medication with plenty of fluids.
                • Space out any medications containing aluminum, magnesium or zinc by at least 2 hours.
                • Can cause diarrhea, nausea or vomiting.
                • Can cause changes in taste, headaches and insomnia.
                Learn more
                More about CleocinSide effectsReviews & ratingsAlternativesFDA package insert
                More about LevaquinSide effectsReviews & ratingsAlternativesFDA package insert