Compare Cleocin vs. Minocycline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cleocin T
(Clindamycin Phosphate)

Solodyn
(Minocycline)

Topical treatment for acne. Cleocin T (Clindamycin Phosphate) is good for treating many bacterial infections and is available as a generic. If you're taking the vaginal form, you have to avoid sex and tampons for the period your doctor tells you to. The topical form can cause skin sensitivity and irritation.Treats bacterial infections. Solodyn (Minocycline) is an effective way to treat certain skin infections, acne, and rosacea, but you'll need to use barrier methods of birth control since it can make birth control pills less effective and cause birth defects.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.794642857142857Cleocin
Reviews for Cleocin T (Clindamycin Phosphate)
57%
of people say Cleocin T (Clindamycin Phosphate) is worth it
43%
say it works well
20%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
CleocinMinocycline
  • Vaginal moniliasis 6%
More Cleocin side effects »

We haven’t found good data for Minocycline side effects.

FDA side effect reports for Minocycline »
How it works
CleocinMinocycline
Cleocin T (Clindamycin Phosphate) is an antibiotic and acne medicine. It kills bacteria by preventing them from reproducing and repairing themselves.Solodyn (Minocycline) is a tetracycline antibiotic. It stops bacteria by preventing them from reproducing and repairing themselves.
Type of medication
CleocinMinocycline
Acne agent
Antibiotic
Prescription only
Antibiotic
Tetracycline
Prescription only
Available as
CleocinMinocycline
  • Topical
  • Cream, gel, or ointment
  • Foam
  • Vaginal cream
  • Vaginal suppository
  • Injection
  • Pill
  • Extended release
  • Extended release capsule
Used for (click to learn more)
CleocinMinocycline
Risk factors for serious side effects
CleocinMinocycline
    • History of liver disease
      Detailed Cleocin T (Clindamycin Phosphate) risks & warnings »
      • Age 8 years or younger
      • Using oral birth control pills
      • Long antibiotic treatment period
          • Women of childbearing age
          Detailed Solodyn (Minocycline) risks & warnings »
          Pregnancy category
          CleocinMinocycline
          BFDA pregnancy category (Probably safe)

          Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

          See the FDA package insert
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
          • Can be taken with or without food.
          No specific food-related info.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
          • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
          No specific sex-related info.
          Sleep
          No specific sleep-related info.No specific sleep-related info.
          Weight
          No specific weight-related info.No specific weight-related info.
          Upsides and benefits
          CleocinMinocycline
          • Available in generic.
          • Topical form treats acne.
          • Available in different oral forms: tablet, capsule, and suspension.
          • Available in forms to treat skin infections and vaginal infections.
          • Used to treat many types of bacterial infections.
          • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
          • Can be taken with or without food.
          • Clinical studies show it's effective against MRSA, a common skin infection, and it's commonly used to treat acne and rosacea.
          • Available as a generic, so it should be reasonably priced.
          • Solodyn (Minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
          • Bacteria are less likely to become resistant to Solodyn (Minocycline) than other tetracycline antibiotics.
          Downsides and risks
          CleocinMinocycline
          • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
          • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
          • If you're allergic to aspirin, your doctor may have to prescribe an alternate.
          • If you have to take live vaccines, talk to your doctor when to take them since Clindamycin can make it less effective.
          • If you're taking the topical form, it can cause sensitivity and irritation.
          • It can make birth control pills less effective, so people should use barrier methods of birth control like condoms or diaphragms while on Solodyn (Minocycline).
          • Can stain your teeth, mouth, and gums if you're using the tablets, or your skin if you're using the topical version, but this is temporary.
          Tips from our pharmacists for people taking the medication
          CleocinMinocycline
          • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
          • Take this medication exactly how your doctor tells you to.
          • Store the suspension at room temperature.
          • If you're using the topical form, it can take a few weeks to see the full effect.
          • Keep the topical form out of your eyes, nose and mouth.
          • If you're using the topical form, Don't put makeup or bandages over it.
          • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
          • Both men and women should use barrier methods of birth control while on Solodyn (Minocycline) since it can cause birth defects and make birth control pills less effective.
          • Can make you dizzy, so be careful if you're getting up from lying down or sitting. Don't drive until you know how it affects you.
          • Can stain your teeth, tongue and gums, but this is temporary.
          • Take this exactly how your doctor or pharmacist tells you until it's all gone.
          • Don't eat any dairy products or take any vitamins within 2 hours of taking Solodyn (Minocycline) because they can make the medication less effective.
          Learn more
          More about CleocinSide effectsReviews & ratingsAlternativesFDA package insert
          More about MinocyclineSide effectsReviews & ratingsAlternativesFDA package insert