Compare Clozaril vs. Geodon

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Clozaril (Clozapine)

Prescription only

Geodon (Ziprasidone)

Prescription only
Helps control your thoughts and actions.

Clozaril (Clozapine) treats schizophrenia when other drugs haven't worked, but you'll have to get blood work done regularly and might gain weight.

Helps control your thoughts and mood.

Geodon (Ziprasidone) treats bipolar disorder and schizophrenia, and causes fewer side effects than similar medicines. It’s not a good choice if you have heart problems.

3.4/ 5 average rating with 23 reviewsforGeodon
Upsides
  • Clinical studies show that Clozaril (Clozapine) is effective in treating schizophrenia when other medications have failed.
  • Has the lowest risk of causing movement problems when compared to other antipsychotic medicines.
  • Clozaril (Clozapine) is available as a normal tablet and as a mint-flavored tablet that dissolves on the tongue without water.
  • Available as a generic, which is cheaper.
  • Geodon (Ziprasidone) can be used with lithium or valproate to better treat bipolar disorder.
  • Geodon (Ziprasidone) can treat agitation in people with schizophrenia by reducing symptoms of anxiety, nervousness, and distress.
  • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
  • The Geodon (Ziprasidone) capsule is available as a generic.
  • The injectable form can treat sudden agitation in schizophrenia when it's not possible to use the capsules.
  • It's available as a pill that you take by mouth daily for continuous treatment and as an injection used for short-term treatment of agitation.
Downsides
  • You need to get blood work done every time you can get a prescription filled for Clozaril (Clozapine).
  • You can only get Clozaril (Clozapine) at certain pharmacies that are registered to provide it.
  • If you don't get Clozaril (Clozapine) within 7 days of it being ready at the pharmacy, then you have to get blood work done again and get a new prescription from your doctor.
  • You need to limit the amount of alcohol you drink while on Clozaril (Clozapine).
  • Elderly people with dementia shouldn’t take Geodon (Ziprasidone).
  • You shouldn’t take Geodon (Ziprasidone) if you have a history of heart problems (slow heart rate, recent heart attack, heart failure, or heart rhythm problems). It’s also not safe to take if you have low potassium or magnesium, or are taking medicines that increase the risk of this happening (diuretics).
  • You'll need to get blood tests before you start taking Geodon (Ziprasidone).
  • It causes slightly less weight gain than similar medicines.
  • Can't take Geodon (Ziprasidone) capsules and injections at the same time. Capsules should be used instead of the injection as soon as possible.
Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Liquid
  • Pill
  • Injection
Price
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Reviews
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23 reviews so far
43%
saidit'sworth it
43%
saiditworked well
30%
saidit'sa big hassle

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Side effects
33possible side effects
  • Drowsiness/Sedation
    39%
  • Salivation
    31%
  • Tachycardia
    25%
  • Dizziness/Vertigo
    19%
  • Constipation
    14%
  • Hypotension
    9%
  • Headache
    7%
  • Tremor
    6%
  • Syncope
    6%
  • Sweating
    6%
  • Dry Mouth
    6%
  • Nausea
    5%
  • Visual Disturbances
    5%
  • Fever
    5%
  • Disturbed Sleep/Nightmares
    4%
  • Restlessness
    4%
  • Hypokinesia/Akinesia
    4%
  • Agitation
    4%
  • Hypertension
    4%
  • Abdominal Discomfort/Heartburn
    4%
  • Weight Gain
    4%
  • Seizures (convulsions)
    3%
  • Rigidity
    3%
  • Akathisia
    3%
  • Confusion
    3%
  • Nausea/Vomiting
    3%
  • Vomiting
    3%
  • Leukopenia/Decreased WBC/Neutropenia
    3%
  • Fatigue
    2%
  • Insomnia
    2%
  • Diarrhea
    2%
  • Urinary Abnormalities
    2%
  • Rash
    2%
See more detailed side effects
12possible side effects
  • Injection Site Pain
    9%
  • Somnolence
    8%
  • Nausea
    4%
  • Headache
    3%
  • Diarrhea
    3%
  • Dizziness
    3%
  • Insomnia
    3%
  • Asthenia
    2%
  • Hypertension
    2%
  • Anxiety
    2%
  • Agitation
    2%
  • Extrapyramidal Syndrome
    2%
See more detailed side effects
Risks and risk factors
  • Fewer white blood cells
  • Low blood pressure | Slow heartbeat | Fainting
    • Dehydration
    • Taking blood pressure medications
  • Seizures
    • Seizure disorder
    • Alcohol abuse
  • Heart problems
    • History of heart problems
  • Increased risk of death
    • Over 65 and having dementia
  • Weight gain
  • Increased blood sugar
    • Diabetes
  • Increased cholesterol
  • Neuroleptic malignant syndrome (NMS)
  • Tardive dyskinesia
  • Return of schizophrenic symptoms
    • Stopping Clozaril (Clozapine) suddenly
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
  • Heart problems
    • History of heart problems
    • Drug interactions
    • Low potassium
    • Low magnesium
  • Neuroleptic malignant syndrome (NMS)
  • Abnormal and involuntary muscle movements
    • Duration of treatment
  • Low blood pressure
  • Risk to fetus
    • Women of childbearing age
See more detailed risks and warnings