Compare Cogentin vs. carbidopa / levodopa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cogentin (benztropine)

Treats Parkinson's disease.

Good for treating tremors caused by Parkinson's and for treating uncontrolled movements in people taking antipsychotics.

Treats Parkinson's disease.

Sinemet (carbidopa / levodopa) is the first choice treatment for Parkinson's disease.

Upsides
  • Cogentin (benztropine) can be used with other medicines for people with more advanced Parkinson's who continue to have tremors.
  • Works by itself in people under 65 who only have Parkinson's tremors and not other symptoms.
  • Can be used in people who have movement problems because they're taking antipsychotic drugs.
  • Available as generic.
  • Sinemet (carbidopa / levodopa) is widely available as a regular pill, a quick dissolving pill or a liquid taken through a feeding tube.
  • Sinemet (carbidopa / levodopa) is available in generic.
Downsides
  • Only treats the tremors in Parkinson's and not the other symptoms.
  • Not recommended in people over 65 or those with memory difficulties or problems thinking clearly because they're more likely to have confusion with Cogentin (benztropine).
  • Can't be used in people who have glaucoma.
  • Can make you very sleepy.
  • Can stain your saliva, sweat and urine a dark color.
  • Will lose its effect over time as your disease progresses.
  • May need to be taken several times during day to control symptoms of Parkinson's disease
  • May cause unusual cravings in some people.
Used for
Dosage forms
  • Pill
  • Injection
  • Pill
  • Dissolving tablet
Price
Lowest price near you
$148.94
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Lowest price near you
$18.44
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Reviews
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Side effects
The Cogentin (benztropine) FDA package insert doesn’t have numbers about how common side effects are.
The Sinemet (carbidopa / levodopa) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Intestinal paralysis

    Taking tricyclic antidepressants

    ...and 1 more risk factors

  • Dehydration

    Over age 65

    ...and 1 more risk factors

  • Heat stroke

    Dehydration

    ...and 3 more risk factors

  • Memory problems and confusion

    Over age 65

    ...and 1 more risk factors

See more detailed risks and warnings
  • Falling asleep during the day

    Taking other medicines for Parkinson's

  • High fever and confusion

    Stopping Sinemet (carbidopa / levodopa) suddenly

  • Lack of impulse control

    Taking other medicines for Parkinson's disease

See more detailed risks and warnings