Compare Combivent vs. Spiriva

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Combivent (Ipratropium / Albuterol)

Prescription only

Spiriva (Tiotropium)

Prescription only
Makes it easier to breathe.

Combivent (Ipratropium / Albuterol) is good for people who need 2 medicines to relieve their COPD symptoms, but you need to be okay with taking it four times a day.

4.6/ 7 average rating with 142 reviewsforCombivent
Makes it easier to breathe.

Spiriva (Tiotropium) works well to reduce COPD symptoms and flare-ups with fewer side effects than some medicines that open airways, but you have to use it every day.

4.8/ 7 average rating with 74 reviewsforSpiriva
Upsides
  • 2-in-1 medicine that opens airways and makes it easier to breathe. Medicines are more effective together than alone.
  • Effectively relieves COPD and asthma symptoms.
  • Respimat formulation has a clear display for dosing, doesn't require shaking, and only needs one inhalation per dose.
  • Helps you breathe easier and lessens the need for a fast-acting (rescue) inhaler.
  • Reduces flare-ups and hospitalizations with fewer side effects compared to some other medicines that open airways.
  • You only need to take it once a day.
Downsides
  • You have to use Combivent four times a day.
  • Can make your heart race.
  • Can make symptoms of enlarged prostate or urinary blockage worse.
  • Can worsen a certain type of glaucoma.
  • Won't cure your COPD (but it will relieve your symptoms).
  • You'll need to use this medicine for a long time, and you have to take it every day.
  • Can make symptoms of enlarged prostate or urinary blockage worse.
  • Can worsen a certain type of glaucoma.
  • You might feel dizzy or have blurry vision while taking this medicine.
Used for
Dosage forms
  • Inhaler
  • Inhaler
Price
Lowest price near you
$32.47
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Lowest price near you
$385.02
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Reviews
142 
63%
think this treatment is worth it
37%
think this treatment works well
13%
think this treatment is a hassle

Have you used Combivent (Ipratropium / Albuterol)?

Leave a review
74 
64%
think this treatment is worth it
46%
think this treatment works well
8%
think this treatment is a hassle

Have you used Spiriva (Tiotropium)?

Leave a review
Side effects
10possible side effects
  • Bronchitis
    12%
  • Upper Respiratory Tract Infection
    11%
  • Headache
    6%
  • Dyspnea
    5%
  • Coughing
    4%
  • Pain
    3%
  • Respiratory Disorders
    3%
  • Nausea
    2%
  • Pharyngitis
    2%
  • Sinusitis
    2%
See more detailed side effects
8possible side effects
  • Respiratory tract Infection
    41%
  • Dry mouth
    16%
  • Pharyngitis
    13%
  • Sinusitis
    11%
  • Chest pain (non-specific)
    7%
  • Urinary tract Infection
    7%
  • Dyspepsia
    6%
  • Rhinitis
    6%
See more detailed side effects
Risks and warnings
  • Heart disease

    History of rapid heartbeat

    ...and 2 more risk factors

  • Worsening glaucoma

    History of narrow-angle glaucoma

    ...and 1 more risk factors

  • Eye problems

    Spraying Combivent (Ipratropium / Albuterol) into eyes

  • Difficulty urinating

    History of urinary bladder blockage (urinary obstruction)

    ...and 1 more risk factors

  • Serious allergic reaction

    History of atropine allergic reaction

  • Low potassium

    Taking Combivent (Ipratropium / Albuterol) with drugs that decrease potassium

    ...and 1 more risk factors

  • Food allergies

    Taking Combivent (Ipratropium / Albuterol) aerosol inhaler

    ...and 2 more risk factors

See more detailed risks and warnings
  • Serious allergic reaction

    History of atropine allergic reaction

  • Worsening glaucoma

    History of narrow-angle glaucoma

  • Difficulty urinating

    History of urinary bladder blockage (urinary obstruction)

    ...and 1 more risk factors

  • Serious allergic reaction

    Severe milk protein allergy

  • Reduced kidney function

    History of moderate to severe kidney disease

  • Feeling dizzy

    Taking with other anticholinergic medications

See more detailed risks and warnings