Compare Complera vs. Emtriva

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Complera (emtricitabine / rilpivirine / tenofovir)

Prescription only

Emtriva (emtricitabine)

Prescription only
Treats HIV infection

Complera (emtricitabine / rilpivirine / tenofovir) is a convenient 3-in-1 medication used to treat HIV infections.

Works with other medicines to treat HIV infection.

Emtriva (emtricitabine) is a first-line and commonly used drug that is taken in combination with other HIV medications to treat or prevent HIV.

Upsides
  • Complera (emtricitabine / rilpivirine / tenofovir) combines three medications into one tablet, so it's easy to take.
  • Complera (emtricitabine / rilpivirine / tenofovir) might be an option for HIV treatment if other HIV drug combinations haven't worked for you.
  • There are drug assistance programs available either through the government (AIDS Drug Assistance Program aka. ADAP) or through the drug manufacturer which can help with drug costs and co-pays.
  • Emtriva (emtricitabine) is a first-line drug option used in combination with other HIV medications to treat HIV.
  • Taken with or without food once a day.
  • Emtriva (emtricitabine) is available in many combination tablets if you are looking to lower the number of pills you need to take daily for HIV treatment.
  • Emtriva (emtricitabine) is available as a capsule as well as liquid form.
Downsides
  • Must be taken with a light meal which includes fat.
  • Cannot be taken with proton pump inhibitors (PPI) like Prilosec or Prevacid. If you need to take an acid reducer, try an antacid like calcium carbonate either 2 hours before or 4 hours after Complera (emtricitabine / rilpivirine / tenofovir). Drugs like Pepcid or Zantac (H2RAs) may also be an option, but these should be taken 12 hours before or 4 hours after Complera (emtricitabine / rilpivirine / tenofovir).
  • Not recommended for patients who have a significantly high level of viral cells or have a very low level of immune cells.
  • Not recommended for patients with kidney damage.
  • Can weaken your bones.
  • Patients with kidney damage will need to be closely monitored by their doctors in order to provide an appropriate dose.
  • Cannot be used by itself to treat or prevent HIV infection.
Used for
Dosage forms
  • Pill
  • Pill
  • Liquid
Price
Lowest price near you
$2741.37
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Lowest price near you
$554.24
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Reviews
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Side effects
3possible side effects
  • Headache
    2%
  • Depressive disorders
    2%
  • Insomnia
    2%
See more detailed side effects
10possible side effects
  • Diarrhea
    23%
  • Nausea
    18%
  • Nasal stuffiness/runniness (Rhinitis)
    18%
  • Rash
    17%
  • Physical weakness and/or lack of energy
    16%
  • Increased cough
    14%
  • Headache
    13%
  • Vomiting
    9%
  • Abdominal pain
    8%
  • Insomnia
    7%
See more detailed side effects
Risks and warnings
  • Lactic acidosis | Enlarged, fatty liver

    Liver disease

    ...and 2 more risk factors

  • Cannot be used to treat Hepatitis B Virus (HBV)

    Hepatitis B Virus infection

  • Mood and behavior changes

    History of mental health problems

  • Decreased bone mineral density

    History of bone fractures

    ...and 1 more risk factors

  • Kidney damage

    History of kidney damage

    ...and 1 more risk factors

  • Hypersensitivity (allergic) reactions

    Prior severe allergic reaction to Complera (emtricitabine / rilpivirine / tenofovir) or any of its individual drug components.

See more detailed risks and warnings
  • Lactic acidosis | Enlarged, fatty liver

    Liver disease

    ...and 2 more risk factors

  • Worsening hepatitis B infection

    Hepatitis B Virus infection

  • Immune reconstitution syndrome

    HIV

    ...and 3 more risk factors

  • Similar medications

    HIV treatment

  • Kidney Damage

    History of kidney damage

See more detailed risks and warnings