Compare Compro vs. Erythromycin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Compro
(Prochlorperazine)

Ery-Tab
(Erythromycin)

Helps you feel less queasy. Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.Prevents and treats infections. Ery-Tab (Erythromycin) works well to treat a variety of bacterial infections, but check for drug interactions before taking it.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
3.95Compro
Reviews for Compro (Prochlorperazine)
45%
of people say Compro (Prochlorperazine) is worth it
35%
say it works well
35%
say it's a big hassle

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Side effects
ComproErythromycin

The Compro FDA package insert doesn’t have numbers about how common side effects are.

More about Compro side effects »

The Erythromycin FDA package insert doesn’t have numbers about how common side effects are.

More about Erythromycin side effects »
How it works
ComproErythromycin
Compro (Prochlorperazine) is an antiemetic (anti-nausea medicine). It works by blocking signals in the part of your brain that causes vomiting.Ery-Tab (Erythromycin) is a macrolide antibiotic that prevents and treats a variety of infections. It works by preventing bacteria from growing and multiplying.
Type of medication
ComproErythromycin
Anti-nausea, Antipsychotic
Antidopaminergic
Prescription only
Antibiotic
Macrolide
Prescription only
Available as
ComproErythromycin
  • Pill
  • Suppository
  • Pill
  • Delayed release tablet
  • Extended release
Used for (click to learn more)
ComproErythromycin
Risk factors for serious side effects
ComproErythromycin
  • Over age 65
  • Dementia
  • Taking antipsychotics
  • History of seizures
  • Age over 65
      • Taking with alcohol
      • Taking other medicines that make you less alert
      Detailed Compro (Prochlorperazine) risks & warnings »
      • History of liver disease
        • Long antibiotic treatment period
        Detailed Ery-Tab (Erythromycin) risks & warnings »
        Pregnancy category
        ComproErythromycin
        NFDA pregnancy category (Unknown)

        The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

        See the FDA package insert
        BFDA pregnancy category (Probably safe)

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        See the FDA package insert
        Alcohol
        • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
        • Don't drink alcohol to avoid intense side effects.
        No specific alcohol-related info.
        Food
        No specific food-related info.
        • Take it with or without food.
        Kidneys and liver
        No specific kidneys and liver-related info.No specific kidneys and liver-related info.
        Sex
        No specific sex-related info.No specific sex-related info.
        Sleep
        • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
        No specific sleep-related info.
        Weight
        No specific weight-related info.
        • It's dosed based on your weight, so different people will have different doses.
        Upsides and benefits
        ComproErythromycin
        • Available in generic, so it's cheap.
        • Can be taken by mouth, as a shot, or rectally.
        • Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
        • It's used to treat a variety of infections caused by bacteria.
        • It comes as an oral suspension and as a tablet.
        • You can get a test done that'll show you if Ery-Tab (Erythromycin) will work for you.
        Downsides and risks
        ComproErythromycin
        • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
        • Can't be used by people over 65 because they can be more affected by the side effects.
        • It can make you more likely to get heatstroke.
        • Interacts with a lot of drugs, so don't take it with colchicine, statin drugs, verapamil, amlodipine, or diltiazem.
        • Diarrhea and other stomach problems are common side effects.
        • Can cause liver problems, so people with previous liver problems need to be closely monitored while on Ery-Tab (Erythromycin).
        Tips from our pharmacists for people taking the medication
        ComproErythromycin
        • Compro comes in different forms. Be clear on which one you were prescribed - swallow tablets orally, unwrap and insert suppositories rectally.
        • You'll likely feel very sleepy, sluggish, or less alert after taking Compro. Avoid driving or other tasks that require your focused attention; be safe.
        • Don't drink alcohol to avoid intense side effects.
        • Taking certain medications for pain, allergies, or mood conditions can worsen the side effects of Compro.
        • Avoid using if you experience seizures (epilepsy).
        • Don't use if you're 65 or older because you're at higher risk for serious side effects.
        • Take it with or without food.
        • It's dosed based on your weight, so different people will have different doses.
        • If you're using the suspension, refrigerate it and use it within 10 days.
        • It's common to feel better before you're supposed to stop taking Ery-Tab (Erythromycin), but make sure to take it for the entire time your doctor prescribed it. Skipping doses or stopping early can lower the drug's effectiveness and increase the chance that the drug won't work as well next time.
        Learn more
        More about ComproSide effectsReviews & ratingsAlternativesFDA package insert
        More about ErythromycinSide effectsAlternativesFDA package insert