Compare Compro vs. Marinol

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Helps you feel less queasy. Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.Coming soon.
How it works
Compro (Prochlorperazine) is an antiemetic (anti-nausea medicine). It works by blocking signals in the part of your brain that causes vomiting.Coming soon.
Type of medication
Anti-nausea, Antipsychotic
Prescription only
Coming soon.
Available as
  • Pill
  • Suppository
  • Pill
Used for (click to learn more)
  • AIDS - Loss of appetite Chemotherapy-induced nausea and vomiting; Prophylaxis
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Reviews & ratings
Button Group. All currently active
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Reviews for Compro (Prochlorperazine)
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Side effects

The Compro FDA package insert doesn’t have numbers about how common side effects are.

More about Compro side effects »

We haven’t found good data for Marinol side effects.

FDA side effect reports for Marinol »
Risk factors for serious side effects
  • Over age 65
  • Dementia
  • Taking antipsychotics
  • History of seizures
  • Age over 65
      • Taking with alcohol
      • Taking other medicines that make you less alert
      Detailed Compro (Prochlorperazine) risks & warnings »
      Coming soon.
      Pregnancy category
      NFDA pregnancy category (Unknown)

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
      • Don't drink alcohol to avoid intense side effects.
      No specific alcohol-related info.
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      No specific sex-related info.No specific sex-related info.
      No specific sleep-related info.No specific sleep-related info.
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      • Available in generic, so it's cheap.
      • Can be taken by mouth, as a shot, or rectally.
      • Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
      Coming soon.
      Downsides and risks
      • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
      • Can't be used by people over 65 because they can be more affected by the side effects.
      • It can make you more likely to get heatstroke.
      Coming soon.
      Tips from our pharmacists for people taking the medication
      • Compro comes in different forms. Be clear on which one you were prescribed - swallow tablets orally, unwrap and insert suppositories rectally.
      • You'll likely feel very sleepy, sluggish, or less alert after taking Compro. Avoid driving or other tasks that require your focused attention; be safe.
      • Don't drink alcohol to avoid intense side effects.
      • Taking certain medications for pain, allergies, or mood conditions can worsen the side effects of Compro.
      • Avoid using if you experience seizures (epilepsy).
      • Don't use if you're 65 or older because you're at higher risk for serious side effects.
      Coming soon.
      Learn more
      More about ComproSide effectsReviews & ratingsAlternativesFDA package insert
      More about MarinolSide effectsReviews & ratingsFDA package insert