Compare Compro vs. Sancuso

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Compro
(Prochlorperazine)

Sancuso
(Granisetron)

Helps you feel less queasy. Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.Coming soon.
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Reviews & ratings
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Have you used Compro (Prochlorperazine)?
Worth itNot sureNot worth it

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Have you used Sancuso (Granisetron)?
Worth itNot sureNot worth it
Side effects
ComproSancuso

The Compro FDA package insert doesn’t have numbers about how common side effects are.

More about Compro side effects »

We haven’t found good data for Sancuso side effects.

FDA side effect reports for Sancuso »
How it works
ComproSancuso
Compro (Prochlorperazine) is an antiemetic (anti-nausea medicine). It works by blocking signals in the part of your brain that causes vomiting.Coming soon.
Type of medication
ComproSancuso
Prescription only
Available as
ComproSancuso
  • Pill
  • Suppository
  • Pill
  • Liquid
  • Patch
Used for
ComproSancuso
  • Chemotherapy Induced Nausea And Vomiting
Risk factors for serious side effects
ComproSancuso
  • Over age 65
  • Dementia
  • Taking antipsychotics
  • History of seizures
  • Age over 65
      • Taking with alcohol
      • Taking other medicines that make you less alert
      Detailed Compro (Prochlorperazine) risks & warnings »
      Coming soon.
      Pregnancy

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Alcohol
      ComproSancuso
      • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
      • Don't drink alcohol to avoid intense side effects.
      No alcohol related info.
      Pain
      ComproSancuso
      • Taking certain medications for pain, allergies, or mood conditions can worsen the side effects of Compro.
      No pain related info.
      Sleep
      ComproSancuso
      • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
      • You'll likely feel very sleepy, sluggish, or less alert after taking Compro. Avoid driving or other tasks that require your focused attention; be safe.
      No sleep related info.
      Upsides and benefits
      ComproSancuso
      • Available in generic, so it's cheap.
      • Can be taken by mouth, as a shot, or rectally.
      • Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
      Coming soon
      Downsides and risks
      ComproSancuso
      • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
      • Can't be used by people over 65 because they can be more affected by the side effects.
      • It can make you more likely to get heatstroke.
      Coming soon
      Tips from our pharmacists for people taking the medication
      ComproSancuso
      • Compro comes in different forms. Be clear on which one you were prescribed - swallow tablets orally, unwrap and insert suppositories rectally.
      • You'll likely feel very sleepy, sluggish, or less alert after taking Compro. Avoid driving or other tasks that require your focused attention; be safe.
      • Don't drink alcohol to avoid intense side effects.
      • Taking certain medications for pain, allergies, or mood conditions can worsen the side effects of Compro.
      • Avoid using if you experience seizures (epilepsy).
      • Don't use if you're 65 or older because you're at higher risk for serious side effects.
      Coming soon
      Learn more
      More about ComproSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Compro (Prochlorperazine)?
      Worth itNot sureNot worth it
      More about SancusoSide effectsFDA package insert
      Have you used Sancuso (Granisetron)?
      Worth itNot sureNot worth it