Compare Compro vs. Sancuso

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Compro
(Prochlorperazine)

Sancuso
(Granisetron)

Helps you feel less queasy. Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.Coming soon.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
3.95Compro
Reviews for Compro (Prochlorperazine)
45%
of people say Compro (Prochlorperazine) is worth it
35%
say it works well
35%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
ComproSancuso

The Compro FDA package insert doesn’t have numbers about how common side effects are.

More about Compro side effects »

We haven’t found good data for Sancuso side effects.

FDA side effect reports for Sancuso »
How it works
ComproSancuso
Compro (Prochlorperazine) is an antiemetic (anti-nausea medicine). It works by blocking signals in the part of your brain that causes vomiting.Coming soon.
Type of medication
ComproSancuso
Anti-nausea, Antipsychotic
Antidopaminergic
Prescription only
Coming soon.
Available as
ComproSancuso
  • Pill
  • Suppository
  • Pill
  • Liquid
  • Patch
Used for (click to learn more)
ComproSancuso
  • Chemotherapy-induced nausea and vomiting
Risk factors for serious side effects
ComproSancuso
  • Over age 65
  • Dementia
  • Taking antipsychotics
  • History of seizures
  • Age over 65
      • Taking with alcohol
      • Taking other medicines that make you less alert
      Detailed Compro (Prochlorperazine) risks & warnings »
      Coming soon.
      Pregnancy category
      ComproSancuso
      NFDA pregnancy category (Unknown)

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      See the FDA package insert
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      Alcohol
      • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
      • Don't drink alcohol to avoid intense side effects.
      No specific alcohol-related info.
      Food
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.
      Sleep
      • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
      No specific sleep-related info.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      ComproSancuso
      • Available in generic, so it's cheap.
      • Can be taken by mouth, as a shot, or rectally.
      • Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
      Coming soon.
      Downsides and risks
      ComproSancuso
      • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
      • Can't be used by people over 65 because they can be more affected by the side effects.
      • It can make you more likely to get heatstroke.
      Coming soon.
      Tips from our pharmacists for people taking the medication
      ComproSancuso
      • Compro comes in different forms. Be clear on which one you were prescribed - swallow tablets orally, unwrap and insert suppositories rectally.
      • You'll likely feel very sleepy, sluggish, or less alert after taking Compro. Avoid driving or other tasks that require your focused attention; be safe.
      • Don't drink alcohol to avoid intense side effects.
      • Taking certain medications for pain, allergies, or mood conditions can worsen the side effects of Compro.
      • Avoid using if you experience seizures (epilepsy).
      • Don't use if you're 65 or older because you're at higher risk for serious side effects.
      Coming soon.
      Learn more
      More about ComproSide effectsReviews & ratingsAlternativesFDA package insert
      More about SancusoSide effectsFDA package insert