Compare Compro vs. scopolamine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Compro (Prochlorperazine)

Prescription only
Helps you feel less queasy.

Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.

4.0/ 7 average rating with 20 reviewsforCompro
Prevents nausea and vomiting.

Transderm-Scop (scopolamine) is a low-hassle patch that works well to prevent nausea and vomiting, but it takes several hours to work.

5.3/ 7 average rating with 26 reviewsforscopolamine
Upsides
  • Available in generic, so it's cheap.
  • Can be taken by mouth, as a shot, or rectally.
  • Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
  • Transderm-Scop (scopolamine) is well tolerated.
  • Prevents nausea for 3 days.
  • Because Transderm-Scop (scopolamine) is a skin patch, it's a good alternative to stopping nausea and vomiting if you're not able to swallow pills.
Downsides
  • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
  • Can't be used by people over 65 because they can be more affected by the side effects.
  • It can make you more likely to get heatstroke.
  • Can only be used for prevention of nausea and vomiting. It can't stop nausea or vomiting that's already happening.
  • The side effects can be worse if you are 65 and older.
  • You might feel sleepy, drowsy, or have blurry vision while taking Transderm-Scop (scopolamine). Taking alcohol or other medicines that make you drowsy can make this effect worse.
  • You're more likely to have heat stroke or feel dehydrated.
  • It takes a few hours for Transderm-Scop (scopolamine) to kick in, so you have to remember to take it beforehand.
Used for
Dosage forms
  • Pill
  • Suppository
  • Patch
Price
Lowest price near you
$4
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Lowest price near you
$27.27
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Reviews
20 
45%
think this treatment is worth it
35%
think this treatment works well
35%
think this treatment is a hassle

Have you used Compro (Prochlorperazine)?

Leave a review
26 
73%
think this treatment is worth it
58%
think this treatment works well
19%
think this treatment is a hassle

Have you used Transderm-Scop (scopolamine)?

Leave a review
Side effects
The Compro (Prochlorperazine) FDA package insert doesn’t have numbers about how common side effects are.
The Transderm-Scop (scopolamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Increased risk of death

    Over age 65

    ...and 2 more risk factors

  • Seizures

    History of seizures

  • Involuntary muscle movements

    Age over 65

  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

See more detailed risks and warnings
  • Increased pressure in the eyes

    Open angle glaucoma

  • Worsening stomach, bowel, or bladder blockages

    Blockages in the stomach, bowels or bladder

  • Skin burns

    MRI examination

  • Worsening seizures or psychosis

    History of seizures

    ...and 1 more risk factors

  • Sleepiness and dizziness

    Taking with alcohol

    ...and 1 more risk factors

See more detailed risks and warnings