Compare Compro vs. scopolamine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Compro
(prochlorperazine)

Transderm-Scop
(scopolamine)

Helps you feel less queasy. Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.Prevents nausea and vomiting. Transderm-Scop (scopolamine) is a low-hassle patch that works well to prevent nausea and vomiting, but it takes several hours to work.
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Coupons for Compro
Best available price for 30 (10mg) tablets of compro
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.95Compro
Reviews for Compro
45%
of people (All ages) say Compro is worth it
35%
say it works well
35%
say it's a big hassle
Have you used Compro (prochlorperazine)?
Worth itNot sureNot worth it
Reviews for scopolamine
73%
-28% worse vs. Compro
58%
-23% worse vs. Compro
19%
-16% worse vs. Compro
Have you used Transderm-Scop (scopolamine)?
Worth itNot sureNot worth it
Side effects
Comproscopolamine

The Compro FDA package insert doesn’t have numbers about how common side effects are.

More about Compro side effects »
  • Dry mouth 12%
  • Dizziness 5%
  • Drowsiness 4%
  • Agitation 2%
  • Visual changes 2%
  • Confusion 1%
  • Dilated pupils 4%
  • Sore throat 1%
More scopolamine side effects »
How it works
Comproscopolamine
Compro (Prochlorperazine) is an antiemetic (anti-nausea medicine). It works by blocking signals in the part of your brain that causes vomiting.Transderm-Scop (scopolamine) is an anti-nausea medicine. It works by blocking signals in the part of your brain that causes vomiting.
Type of medication
Comproscopolamine
Prescription onlyPrescription only
Available as
Comproscopolamine
  • Pill
  • Suppository
  • Patch
Used for
Comproscopolamine
Risk factors for serious side effects
Comproscopolamine
  • Over age 65
  • Dementia
  • Taking antipsychotics
  • History of seizures
  • Age over 65
Detailed Compro (prochlorperazine) risks & warnings »
  • Open angle glaucoma
  • Blockages in the stomach, bowels or bladder
  • MRI examination
  • History of seizures
  • History of psychosis
Detailed Transderm-Scop (scopolamine) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
Comproscopolamine
  • Don't drink alcohol to avoid intense side effects.
No alcohol related info.
Pain
Comproscopolamine
  • Taking certain medications for pain, allergies, or mood conditions can worsen the side effects of Compro.
No pain related info.
Sleep
Comproscopolamine
  • You'll likely feel very sleepy, sluggish, or less alert after taking Compro. Avoid driving or other tasks that require your focused attention; be safe.
  • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
  • You might feel sleepy, drowsy, or have blurry vision while taking Transderm-Scop (scopolamine). Taking alcohol or other medicines that make you drowsy can make this effect worse.
Upsides and benefits
Comproscopolamine
  • Available in generic, so it's cheap.
  • Can be taken by mouth, as a shot, or rectally.
  • Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
  • Transderm-Scop (scopolamine) is well tolerated.
  • Prevents nausea for 3 days.
  • Because Transderm-Scop (scopolamine) is a skin patch, it's a good alternative to stopping nausea and vomiting if you're not able to swallow pills.
Downsides and risks
Comproscopolamine
  • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
  • Can't be used by people over 65 because they can be more affected by the side effects.
  • It can make you more likely to get heatstroke.
  • Can only be used for prevention of nausea and vomiting. It can't stop nausea or vomiting that's already happening.
  • The side effects can be worse if you are 65 and older.
  • You might feel sleepy, drowsy, or have blurry vision while taking Transderm-Scop (scopolamine). Taking alcohol or other medicines that make you drowsy can make this effect worse.
  • You're more likely to have heat stroke or feel dehydrated.
  • It takes a few hours for Transderm-Scop (scopolamine) to kick in, so you have to remember to take it beforehand.
Tips from our pharmacists for people taking the medication
Comproscopolamine
  • Compro comes in different forms. Be clear on which one you were prescribed - swallow tablets orally, unwrap and insert suppositories rectally.
  • You'll likely feel very sleepy, sluggish, or less alert after taking Compro. Avoid driving or other tasks that require your focused attention; be safe.
  • Don't drink alcohol to avoid intense side effects.
  • Taking certain medications for pain, allergies, or mood conditions can worsen the side effects of Compro.
  • Avoid using if you experience seizures (epilepsy).
  • Don't use if you're 65 or older because you're at higher risk for serious side effects.
  • Starts working in 6 to 8 hours.
  • Apply Transderm-Scop (scopolamine) to a clean, dry, hairless area of the skin behind the ear. Press down for 30 seconds to make sure the patch stays firmly.
  • After handling the patch, make sure to wash your hands with soap and water to avoid accidental contact with your eyes.
  • If the patch comes off, throw it away and use a new patch.
  • You can prevent skin irritation by alternating ears and washing the area of your ear that you had placed the patch on.
  • If you're using this before surgery, place it the day before, then leave it on until the day after your surgery.
  • Take the patch off before you have an MRI because it can cause the skin to burn.
Learn more
More about ComproSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Compro (prochlorperazine)?
Worth itNot sureNot worth it
More about scopolamineSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Transderm-Scop (scopolamine)?
Worth itNot sureNot worth it