Compare Coreg vs. Catapres

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coreg
(Carvedilol)

Catapres
(Clonidine)

Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure. Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.79Coreg
Reviews for Coreg (Carvedilol)
53%
of people (All ages) say Coreg (Carvedilol) is worth it
46%
say it works well
18%
say it's a big hassle
406 reviews
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
Reviews for Catapres (Clonidine)
42%
11% vs. Coreg (Carvedilol)
33%
13% vs. Coreg (Carvedilol)
35%
17% vs. Coreg (Carvedilol)
Have you used Catapres (Clonidine)?
Worth itNot sureNot worth it
Side effects
CoregCatapres
  • Leg or ankle swelling 1%
More Coreg side effects »

The Catapres FDA package insert doesn’t have numbers about how common side effects are.

More about Catapres side effects »
How it works
CoregCatapres
Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Catapres (Clonidine) is an alpha-2 agonist. It works in the brain to tell your blood vessels to relax, and it lowers the activity of certain stress hormones. This lowers blood pressure.
Type of medication
CoregCatapres
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Alpha agonist
Prescription only
Available as
CoregCatapres
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Patch
Used for (click to learn more)
CoregCatapres
Risk factors for serious side effects
CoregCatapres
  • Abrupt discontinuation of Coreg (Carvedilol)
  • Congestive heart failure
  • Increasing the dose of Coreg (Carvedilol)
  • Diabetes
  • Major surgery requiring anesthesia
Detailed risks & warnings »
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
Detailed risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
CoregCatapres
  • You have to take Carvedilol with food.
  • Take it with food.
No food related info.
Sleep
CoregCatapres
No sleep related info.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
Upsides and benefits
CoregCatapres
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Available in a weekly patch for people that aren't good at taking medicine by mouth.
  • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
  • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
Downsides and risks
CoregCatapres
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
CoregCatapres
  • Take it with food.
  • Can cause dizziness in the first few days.
  • Can cause fatigue and erectile dysfunction.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Don't stop taking this medicine suddenly.
  • Usually taken together with other medicines for better blood pressure control.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • If side effects don't go away, talk to your doctor about alternatives.
  • The weekly patch form can have fewer side effects.
  • Extended release tablet also used to treat ADHD.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Don't stop taking this medicine suddenly.
Learn more
More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
More about CatapresSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Catapres (Clonidine)?
Worth itNot sureNot worth it