Compare Coreg vs. Lisinopril

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coreg
(Carvedilol)

Zestril
(Lisinopril)

Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure. Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.79Coreg
Reviews for Coreg (Carvedilol)
53%
of people (All ages) say Coreg (Carvedilol) is worth it
46%
say it works well
18%
say it's a big hassle
406 reviews
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
Reviews for Zestril (Lisinopril)
61%
+8% better vs. Coreg (Carvedilol)
51%
+5% better vs. Coreg (Carvedilol)
14%
+4% better vs. Coreg (Carvedilol)
687 reviews
Have you used Zestril (Lisinopril)?
Worth itNot sureNot worth it
Side effects
CoregLisinopril
  • Dizziness 13%
  • Fatigue 2%
  • High blood sugar 4%
  • Diarrhea 6%
  • Weight increase 3%
  • Nausea 4%
  • Abnormally slow heartbeat 8%
  • Low blood pressure 6%
  • Headache 1%
More Coreg side effects »
  • Headache 4%
  • Dizziness 3%
  • Cough 3%
  • Diarrhea 1%
  • Fatigue 2%
  • Infection 2%
  • Low blood pressure 4%
  • Chest pain 2%
More Lisinopril side effects »
How it works
CoregLisinopril
Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Zestril (Lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
CoregLisinopril
Prescription only
Prescription only
Available as
CoregLisinopril
  • Pill
  • Extended release
  • Pill
Used for
CoregLisinopril
Risk factors for serious side effects
CoregLisinopril
  • Abrupt discontinuation of Coreg (Carvedilol)
      • Congestive heart failure
      • Increasing the dose of Coreg (Carvedilol)
      • Diabetes
      • Major surgery requiring anesthesia
        Detailed Coreg (Carvedilol) risks & warnings »
        • Women of childbearing age
          • African descent
          • Current kidney problems
          • Medicine that increase potassium
          • Use of salt substitute
          Detailed Zestril (Lisinopril) risks & warnings »
          Pregnancy

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          Food
          CoregLisinopril
          • You have to take Carvedilol with food.
          • Take it with food.
          No food related info.
          Kidneys and liver
          CoregLisinopril
          No kidneys and liver related info.
          • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
          • Requires routine blood tests to check kidney function.
          Upsides and benefits
          CoregLisinopril
          • A first-choice treatment to prevent chest pain (angina).
          • A first-choice treatment for heart failure and heart attack.
          • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
          • A first-choice blood pressure treatment for many people.
          • Lowers the risk of heart attack and stroke.
          • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
          • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
          Downsides and risks
          CoregLisinopril
          • You have to take Carvedilol with food.
          • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
          • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
          • Can hide symptoms of low blood sugar if you're diabetic.
          • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
          • Requires a yearly blood test to see how the medicine is affecting your body.
          • Not safe to use if you're pregnant.
          Tips from our pharmacists for people taking the medication
          CoregLisinopril
          • Take it with food.
          • Can cause dizziness in the first few days.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Can cause fatigue and erectile dysfunction.
          • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
          • Don't stop taking this medicine suddenly.
          • Can cause dizziness in the first few days.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
          • Requires routine blood tests to check kidney function.
          • Don't take it if you're pregnant.
          Learn more
          More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
          Have you used Coreg (Carvedilol)?
          Worth itNot sureNot worth it
          More about LisinoprilSide effectsReviews & ratingsAlternativesFDA package insert
          Have you used Zestril (Lisinopril)?
          Worth itNot sureNot worth it