Compare Coreg vs. Lopressor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coreg
(Carvedilol)

Lopressor
(metoprolol tartrate)

Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.79Coreg
Reviews for Coreg
53%
of people (All ages) say Coreg is worth it
46%
say it works well
18%
say it's a big hassle
406 reviews
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
Reviews for Lopressor
62%
-9% worse vs. Coreg
47%
-1% worse vs. Coreg
15%
-3% worse vs. Coreg
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Side effects
CoregLopressor
  • Edema peripheral 1%
  • Edema dependent 2%
  • Hypercholesterolemia 1%
  • Digoxin level increased 1%
  • Edema generalized 2%
  • Vision abnormal 3%
  • Vomiting 2%
More Coreg side effects »
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Depression 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Tiredness 10%
  • Dizziness 10%
  • First-degree heart block 3%
  • Low blood pressure 4%
More Lopressor side effects »
How it works
CoregLopressor
Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
CoregLopressor
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
CoregLopressor
  • Pill
  • Extended release
  • Pill
Used for
CoregLopressor
Risk factors for serious side effects
CoregLopressor
  • Abrupt discontinuation of Coreg (Carvedilol)
  • Congestive heart failure
  • Increasing the dose of Coreg (Carvedilol)
  • Diabetes
  • Major surgery requiring anesthesia
Detailed Coreg (Carvedilol) risks & warnings »
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
CoregLopressor
  • Take it with food.
  • You have to take Carvedilol with food.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
Pain
CoregLopressor
No pain related info.
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
Upsides and benefits
CoregLopressor
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
Downsides and risks
CoregLopressor
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
CoregLopressor
  • Take it with food.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause fatigue and erectile dysfunction.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
Learn more
More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it