Compare Coreg vs. Toprol XL

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coreg
(Carvedilol)

Toprol Xl
(Metoprolol Succinate)

Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure and controls heart rate. Toprol Xl (Metoprolol Succinate) is good for controlling chest pain and treating heart failure and heart attack. You can't miss doses.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.7890818858560795Coreg
Reviews for Coreg (Carvedilol)
54%
of people say Coreg (Carvedilol) is worth it
46%
say it works well
18%
say it's a big hassle
Reviews for Toprol Xl (Metoprolol Succinate)
60%
+6% vs. Coreg (Carvedilol)
55%
+9% vs. Coreg (Carvedilol)
13%
+5% vs. Coreg (Carvedilol)
Side effects
CoregToprol XL
  • Dizziness 13%
  • Abnormally slow heartbeat 7%
  • Low blood pressure 6%
  • Diarrhea 6%
  • High blood sugar 4%
  • Nausea 4%
  • Vision abnormal 3%
  • Fainting 3%
  • Muscle weakness 2%
  • Edema dependent 2%
More Coreg side effects »
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • Heart block 3%
More Toprol XL side effects »
How it works
CoregToprol XL
Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Toprol Xl (Metoprolol Succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
CoregToprol XL
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Available as
CoregToprol XL
  • Pill
  • Extended release
  • Pill
  • Extended release
Used for (click to learn more)
CoregToprol XL
Risk factors for serious side effects
CoregToprol XL
  • Abrupt discontinuation of Coreg (Carvedilol)
      • Congestive heart failure
      • Increasing the dose of Coreg (Carvedilol)
      • Diabetes
      • Major surgery requiring anesthesia
        Detailed Coreg (Carvedilol) risks & warnings »
        • Diabetes
          • Coronary artery disease
          • Heart failure
          • Major surgery requiring anesthesia
          • History of asthma
          Detailed Toprol Xl (Metoprolol Succinate) risks & warnings »
          Pregnancy category
          CoregToprol XL
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          • You have to take Carvedilol with food.
          • Take it with food.
          No specific food-related info.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.No specific sleep-related info.
          Weight
          • You may notice worsening symptoms of heart failure if your prescriber decides to increase your dosage of Coreg (Carvedilol). Tell your doctor if you noticed increased swelling around your legs or ankles, sudden weight gain or sudden shortness of breath as they may make changes to your medications for heart failure.
          No specific weight-related info.
          Upsides and benefits
          CoregToprol XL
          • A first-choice treatment to prevent chest pain (angina).
          • A first-choice treatment for heart failure and heart attack.
          • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
          • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
          • A first-choice treatment for heart failure. May prevent long-term heart damage.
          • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
          • Toprol XL is the extended release version of Lopressor.
          Downsides and risks
          CoregToprol XL
          • You have to take Carvedilol with food.
          • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
          • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
          • Can hide symptoms of low blood sugar if you're diabetic.
          • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
          • You can't miss doses. Stopping Toprol XL suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
          • Can hide symptoms of low blood sugar if you're diabetic.
          Tips from our pharmacists for people taking the medication
          CoregToprol XL
          • Take it with food.
          • Can cause fatigue and erectile dysfunction.
          • Can cause dizziness in the first few days.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
          • Don't stop taking this medicine suddenly.
          • Can cause fatigue and headache.
          • Extended release version. Also comes in immediate release called Lopressor (metoprolol tartrate).
          • Can cause dizziness in the first few days.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
          • Don't stop taking this medicine suddenly.
          Learn more
          More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
          More about Toprol XLSide effectsReviews & ratingsAlternativesFDA package insert