Compare Cortisone vs. Dexamethasone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cortisone

Decadron
(Dexamethasone)

Coming soon.Lowers inflammation and suppresses your immune system. Decadron (Dexamethasone) is identical to an essential hormone that humans produce and has been proven to work safely.
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  • Cost for (45) 25mg tablets of Cortisone
Reviews & ratings
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Have you used Cortisone?
Worth itNot sureNot worth it

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Have you used Decadron (Dexamethasone)?
Worth itNot sureNot worth it
Side effects
CortisoneDexamethasone

We haven’t found good data for Cortisone side effects.

FDA side effect reports for Cortisone »

The Dexamethasone FDA package insert doesn’t have numbers about how common side effects are.

More about Dexamethasone side effects »
How it works
CortisoneDexamethasone
Coming soon.Decadron (Dexamethasone) is a short-acting corticosteroid. It lowers inflammation by preventing your capillaries (small blood vessels) from leaking out excess fluid and chemicals that cause swelling.
Type of medication
CortisoneDexamethasone
Coming soon.
Glucocorticoid
Synthetic
Prescription only
Available as
CortisoneDexamethasone
  • Pill
  • Pill
  • Liquid
Used for (click to learn more)
CortisoneDexamethasone
  • Acute lymphoid leukemia Adrenal insufficiency Allergic disorder Chronic lymphoid leukemia Collagen disease Disorder of endocrine system Disorder of eye Disorder of gastrointestinal tract Disorder of hematopoietic structure Disorder of respiratory system Disorder of skin Hodgkin's disease Hypercalcemia of malignancy Inflammatory disorder of musculoskeletal system Mycosis fungoides Neoplastic disease Nephrotic syndrome Non-Hodgkin's lymphoma Trichinosis Tuberculosis of meninges; Adjunct
Risk factors for serious side effects
CortisoneDexamethasone
Coming soon.
  • Lowering dose or stopping too quickly especially after long-term treatment
  • Stress such as trauma, surgery or infection
  • Long-term treatment
  • Not vaccinated against viral diseases
  • Contact with people who have viral illness
  • History of bacterial or viral conditions
  • Duration of treatment
  • History of psychiatric conditions
  • Dose of Decadron (Dexamethasone)
  • Duration of treatment
  • Women of childbearing age
Detailed Decadron (Dexamethasone) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
CortisoneDexamethasone
No kidneys and liver related info.
  • Adrenal suppression leading to adrenal crisis can occur if you lower your dose or stop taking Decadron (Dexamethasone) too quickly. Symptoms include joint or muscle pain, extreme low energy and depression. Changes in your Decadron (Dexamethasone) dose need to be done slowly over time. Talk to your doctor before you make any changes or stop the medication.
Weight
CortisoneDexamethasone
No weight related info.
  • Some people gain weight while taking Decadron (Dexamethasone) or can experience other side effects like mood changes.
Upsides and benefits
CortisoneDexamethasone
Coming soon
  • Treats a large variety of inflammatory disorders including asthma, dermatitis, drug reactions, rashes, and endocrine disorders.
  • Can help prevent nausea, especially when it's caused by chemotherapy.
  • You can get it orally or as an injection.
Downsides and risks
CortisoneDexamethasone
Coming soon
  • Can't be used on its own to treat low cortisol levels.
  • Since it suppresses your immune system, you're more likely to get infections.
  • You can't take Decadron (Dexamethasone) if you have a systemic fungal infection.
  • Shouldn't be used if you have a stomach ulcer.
  • Can decrease bone formation and lead to an increased risk of osteoporosis.
Tips from our pharmacists for people taking the medication
CortisoneDexamethasone
Coming soon
  • The lowest possible dose of corticosteroids should be used to control your symptoms.
  • When reducing or stopping the dose, do it very slowly and follow your doctor's instructions exactly to prevent major health emergencies.
  • If you used Decadron (Dexamethasone) for a long time, you could get withdrawal symptoms like muscle pain, joint pain, and malaise.
  • Some people gain weight while taking Decadron (Dexamethasone) or can experience other side effects like mood changes.
  • Don't get live or live/attenuated vaccines while on this. Killed or inactivated vaccines are fine.
Learn more
More about CortisoneSide effectsReviews & ratingsFDA package insert
Have you used Cortisone?
Worth itNot sureNot worth it
More about DexamethasoneSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Decadron (Dexamethasone)?
Worth itNot sureNot worth it