Compare Cortisone vs. Hydrocortisone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

cortisone

Anusol Hc
(hydrocortisone)

Coming soon.Treats itchy or irritated skin. Anusol Hc (Hydrocortisone) is a good topical steroid to try for treating minor rashes or skin irritation.
Reviews & ratings
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Have you used Cortisone?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Anusol Hc (hydrocortisone)?
Worth itNot sureNot worth it
Side effects
CortisoneHydrocortisone

We haven’t found good data for Cortisone side effects.

FDA side effect reports for Cortisone »

We haven’t found good data for Hydrocortisone side effects.

FDA side effect reports for Hydrocortisone »
How it works
CortisoneHydrocortisone
Coming soon.Anusol Hc (Hydrocortisone) is a topical steroid that works by decreasing skin itching, swelling, and redness.
Type of medication
CortisoneHydrocortisone
Over-the-counter
Available as
CortisoneHydrocortisone
  • Pill
  • Cream, gel, or ointment
  • Lotion
  • Topical solution
Used for
CortisoneHydrocortisone
  • Acute Lymphoid Leukemia Adrenal Insufficiency Allergic Disorder Chronic Lymphoid Leukemia Collagen Disease Disorder Of Endocrine System Disorder Of Eye Disorder Of Gastrointestinal Tract Disorder Of Hematopoietic Structure Disorder Of Respiratory System Disorder Of Skin Hodgkins Disease Hypercalcemia Of Malignancy Inflammatory Disorder Of Musculoskeletal System Mycosis Fungoides Neoplastic Disease Nephrotic Syndrome Non Hodgkins Lymphoma Trichinosis Tuberculosis Of Meninges Adjunct
  • Skin Inflammation
Risk factors for serious side effects
CortisoneHydrocortisone
    Coming soon.
    • Long-term treatment
    • Not vaccinated against viral diseases
    • Contact with people who have viral illness
    • History of bacterial or viral conditions
    Detailed Anusol Hc (hydrocortisone) risks & warnings »
    Pregnancy

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Upsides and benefits
    CortisoneHydrocortisone
    Coming soon
    • Relieves itchy and irritated skin.
    • Doesn't cause the same types of side effects that oral forms of steroids do.
    • It's available over the counter in the drugstore.
    • Most people have very few side effects.
    Downsides and risks
    CortisoneHydrocortisone
    Coming soon
    • It's not a strong steroid, so it doesn't work for everyone.
    • When used longer than a week, it can cause skin-thinning and make it harder for broken skin to heal.
    Tips from our pharmacists for people taking the medication
    CortisoneHydrocortisone
    Coming soon
    • Rub a thin layer of Anusol Hc (Hydrocortisone) into the area of skin that is affected.
    • Don't rub it into broken areas of skin and leave the area uncovered.
    • Wash your hands after applying it each time.
    • Don't use Anusol Hc (Hydrocortisone) more often than your doctor or the package label recommends.
    • Wait at least 30 minutes between applying moisturizing lotions and this medication.
    • Talk to your doctor if your skin gets worse or hasn't improved in seven days.
    Learn more
    More about CortisoneSide effectsReviews & ratingsFDA package insert
    Have you used Cortisone?
    Worth itNot sureNot worth it
    More about HydrocortisoneSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Anusol Hc (hydrocortisone)?
    Worth itNot sureNot worth it