Compare Cortisone vs. Medrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

cortisone

SOLU-medrol
(methylprednisolone)

Coming soon.Calms down your immune system. SOLU-medrol (methylprednisolone) is very effective for controlling allergic reactions and many types of inflammatory conditions, but it is associated with serious and potentially life-threatening side effects if you have to take it for a long time.
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Best available price for 45 (25mg) tablets of cortisone
Reviews & ratings
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Have you used Cortisone?
Worth itNot sureNot worth it
Reviews for Medrol
59%
-9% worse vs. Cortisone
53%
-3% worse vs. Cortisone
23%
+23% better vs. Cortisone
Have you used SOLU-medrol (methylprednisolone)?
Worth itNot sureNot worth it
Side effects
CortisoneMedrol

We haven’t found good data for Cortisone side effects.

FDA side effect reports for Cortisone »

The Medrol FDA package insert doesn’t have numbers about how common side effects are.

More about Medrol side effects »
How it works
CortisoneMedrol
Coming soon.SOLU-medrol (methylprednisolone) is a corticosteroid that is similar to a hormone your body naturally makes in response to stress. It helps reduce swelling and blocks the actions of your immune system that normally would cause pain, discomfort, or harm.
Type of medication
CortisoneMedrol
Prescription only
Available as
CortisoneMedrol
  • Pill
  • Pill
  • Injection
Used for
CortisoneMedrol
  • Acute Lymphoid Leukemia Adrenal Insufficiency Allergic Disorder Chronic Lymphoid Leukemia Collagen Disease Disorder Of Endocrine System Disorder Of Eye Disorder Of Gastrointestinal Tract Disorder Of Hematopoietic Structure Disorder Of Respiratory System Disorder Of Skin Hodgkins Disease Hypercalcemia Of Malignancy Inflammatory Disorder Of Musculoskeletal System Mycosis Fungoides Neoplastic Disease Nephrotic Syndrome Non Hodgkins Lymphoma Trichinosis Tuberculosis Of Meninges Adjunct
Risk factors for serious side effects
CortisoneMedrol
    Coming soon.
    • Taking high doses of SOLU-medrol (methylprednisolone) for a long period of time
    • Young children
    • Stress such as trauma, injury, or infection
    • Taking other medicines that weaken the immune system
    • Taking SOLU-medrol (methylprednisolone) for a long time
    Detailed SOLU-medrol (methylprednisolone) risks & warnings »
    Pregnancy

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Food
    CortisoneMedrol
    No food related info.
    • Take SOLU-medrol (methylprednisolone) in the morning with food to lower your chances of getting stomach upset and having trouble sleeping. For an evening dose, it is best to take the medicine at least 2 to 3 hours before bedtime.
    Kidneys and liver
    CortisoneMedrol
    No kidneys and liver related info.
    • SOLU-medrol (methylprednisolone) can cause high blood pressure, unexplained weight gain, and other changes in the way your kidneys work. If you have a history of heart failure, high blood pressure, or kidney problems, talk to your doctor first before using this medicine.
    Upsides and benefits
    CortisoneMedrol
    Coming soon
    • SOLU-medrol (methylprednisolone) is effective for treating a variety of conditions involving the immune system.
    • Can help improve energy and stimulate your appetite.
    • Works quickly to provide relief for swelling, rash, asthma attacks, and pain.
    • SOLU-medrol (methylprednisolone) is available in a generic form.
    • Available as blister packs that organize tablets into specific days and times for easier administration.
    Downsides and risks
    CortisoneMedrol
    Coming soon
    • SOLU-medrol (methylprednisolone) can cause unwanted side effects such as mood changes, trouble sleeping, and increase in blood pressure as well as blood sugar at higher doses.
    • Long-term use can cause problems to your skin, bones, eyes, and place you at a higher risk for infections.
    • If SOLU-medrol (methylprednisolone) is used for more than 2 weeks, you will need to work with a doctor to get off of the medicine by gradually decreasing the dose.
    • SOLU-medrol (methylprednisolone) can cause harm to an unborn baby, so it might not be a good option for pregnant women.
    • Might cause abnormal growth and development when used in children.
    Tips from our pharmacists for people taking the medication
    CortisoneMedrol
    Coming soon
    • Take SOLU-medrol (methylprednisolone) in the morning with food to lower your chances of getting stomach upset and having trouble sleeping. For an evening dose, it is best to take the medicine at least 2 to 3 hours before bedtime.
    • SOLU-medrol (methylprednisolone) can increase your appetite, make your body retain more water, and cause changes to your mood.
    • SOLU-medrol (methylprednisolone) can increase your blood pressure and blood sugar at higher doses. If you have high blood pressure or diabetes, it is important that you check your blood pressure and blood sugar regularly while taking this medicine.
    • If you need to take SOLU-medrol (methylprednisolone) for longer than 2 weeks, you may need to gradually stop taking this medicine. Take it exactly as your doctor told you and do not stop suddenly.
    • While you are on this medicine, don't get any live vaccines, unless approved by your doctor.
    • SOLU-medrol (methylprednisolone) can increase your chances of getting an infection. Call your doctor right away if you have a fever, chills, flu-like symptoms, cough, pain with passing urine, or a wound that will not heal.
    Learn more
    More about CortisoneSide effectsReviews & ratingsFDA package insert
    Have you used Cortisone?
    Worth itNot sureNot worth it
    More about MedrolSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used SOLU-medrol (methylprednisolone)?
    Worth itNot sureNot worth it