Compare Cortisone vs. Prednisone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coming soon.

Cortisone

Deltasone
(Prednisone)

Coming soon.Calms down your immune system. Deltasone (Prednisone) is a common oral corticosteroid that's great for controlling the unwanted symptoms from your immune responses and will make you feel better. There are lots of side effects but most of are tolerable or can be managed.
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Reviews & ratings
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Have you used Cortisone?
Worth itNot sureNot worth it
Reviews for Deltasone (Prednisone)
59%
+9% vs. Cortisone
45%
5% vs. Cortisone
20%
20% vs. Cortisone
540 reviews
Have you used Deltasone (Prednisone)?
Worth itNot sureNot worth it
Side effects
CortisonePrednisone

We haven’t found good data for Cortisone side effects.

FDA side effect reports for Cortisone »

The Prednisone FDA package insert doesn’t have numbers about how common side effects are.

More about Prednisone side effects »
How it works
CortisonePrednisone
Coming soon.Deltasone (Prednisone) is a corticosteroid that's similar to what your body naturally makes. It reduces swelling and other immune responses that can cause you pain, discomfort, or harm.
Type of medication
CortisonePrednisone
Coming soon.
Anti-inflammatory, Immunosuppressant
Corticosteroid
Prescription only
Available as
CortisonePrednisone
  • Pill
  • Pill
  • Extended release
  • Liquid
Used for (click to learn more)
CortisonePrednisone
  • Acute lymphoid leukemia Adrenal insufficiency Allergic disorder Chronic lymphoid leukemia Collagen disease Disorder of endocrine system Disorder of eye Disorder of gastrointestinal tract Disorder of hematopoietic structure Disorder of respiratory system Disorder of skin Hodgkin's disease Hypercalcemia of malignancy Inflammatory disorder of musculoskeletal system Mycosis fungoides Neoplastic disease Nephrotic syndrome Non-Hodgkin's lymphoma Trichinosis Tuberculosis of meninges; Adjunct
Risk factors for serious side effects
CortisonePrednisone
  • Lowering dose or stopping too quickly especially after long-term treatment
  • Stress such as trauma, surgery or infection
  • Long-term treatment
  • Not vaccinated against viral diseases
  • Contact with people who have viral illness
Detailed risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
CortisonePrednisone
No food related info.
  • Take with food to decrease stomach upset.
Kidneys and liver
CortisonePrednisone
No kidneys and liver related info.
  • Adrenal suppression leading to adrenal crisis can occur if you lower your dose or stop taking Deltasone (Prednisone) too quickly. Symptoms include joint or muscle pain, extreme low energy and depression. Changes in your Deltasone (Prednisone) dose need to be done slowly over time. Talk to your doctor before you make any changes or stop the medication.
Upsides and benefits
CortisonePrednisone
Coming soon
  • Steroid magic, can help you feel better, have more energy and get more appetite.
  • Useful for many conditions.
  • Short-term use in controlling immune responses that are causing you discomfort, and works quickly to relieve symptoms like swelling, rash, asthma attacks, gout attacks.
  • Long-term use in suppressing the immune system from causing your body harm, like many autoimmune related conditions.
Downsides and risks
CortisonePrednisone
Coming soon
  • Lots of side effects, especially with long term use.
  • Short-term use can cause mood changes, trouble sleeping and increase in blood pressure, blood sugar, and possible water retention.
  • Long-term use can cause problems with skin, bone, eye health and put you at a higher risk for infections.
  • People with certain conditions will have to pay extra attention to their symptoms or may have to adjust the dose of other medicines when taking Prednisone.
  • When using corticosteroids for more than 1 week, you will need to work with a doctor to get off the medicine slowly.
  • Only available as an oral medicine so the rest of your body will be exposed to the medicine.
Tips from our pharmacists for people taking the medication
CortisonePrednisone
Coming soon
  • The dose and duration on how long you need the medicine depends on your condition and response.
  • Take it exactly as your doctor prescribed.
  • Take with food to decrease stomach upset.
  • Can cause trouble sleeping. Take in the morning or 2-3 hours before bed if more than one dose is needed.
  • Can cause changes in mood, blood pressure, blood sugar, and water retention.
  • You should check your blood pressure and blood sugar when taking this medicine if you already have high blood pressure or diabetes.
  • A taper is is often needed to stop the medicine, especially if you've been on it for more than 1 week.
Learn more
More about CortisoneSide effectsReviews & ratingsFDA package insert
Have you used Cortisone?
Worth itNot sureNot worth it
More about PrednisoneSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Deltasone (Prednisone)?
Worth itNot sureNot worth it