Compare Cortisone vs. prednisone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

cortisone

Rayos
(prednisone)

Coming soon.Calms down your immune system. Rayos (prednisone) is effective for controlling allergic reactions and conditions involving the immune system. It can quickly make you feel better, but Rayos (prednisone) can cause serious complications and side effects if taken for a long time.
Reviews & ratings
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Have you used Cortisone?
Worth itNot sureNot worth it
Reviews for prednisone
59%
-9% worse vs. Cortisone
45%
+5% better vs. Cortisone
20%
+20% better vs. Cortisone
540 reviews
Have you used Rayos (prednisone)?
Worth itNot sureNot worth it
Side effects
Cortisoneprednisone

We haven’t found good data for Cortisone side effects.

FDA side effect reports for Cortisone »

The prednisone FDA package insert doesn’t have numbers about how common side effects are.

More about prednisone side effects »
How it works
Cortisoneprednisone
Coming soon.Rayos (prednisone) is a corticosteroid similar to a hormone your body naturally makes in response to stress. It helps reduce swelling and blocks the actions of your immune system that normally would cause pain, discomfort, or harm.
Type of medication
Cortisoneprednisone
Prescription only
Available as
Cortisoneprednisone
  • Pill
  • Pill
  • Delayed release pill
  • Liquid
Used for
Cortisoneprednisone
  • Acute Lymphoid Leukemia Adrenal Insufficiency Allergic Disorder Chronic Lymphoid Leukemia Collagen Disease Disorder Of Endocrine System Disorder Of Eye Disorder Of Gastrointestinal Tract Disorder Of Hematopoietic Structure Disorder Of Respiratory System Disorder Of Skin Hodgkins Disease Hypercalcemia Of Malignancy Inflammatory Disorder Of Musculoskeletal System Mycosis Fungoides Neoplastic Disease Nephrotic Syndrome Non Hodgkins Lymphoma Trichinosis Tuberculosis Of Meninges Adjunct
Risk factors for serious side effects
Cortisoneprednisone
    Coming soon.
    • Taking high doses of Rayos (prednisone) for a long period of time
    • Young children
    • Stress such as trauma, injury, or infection
    • Taking other medicines that weaken the immune system
    • Taking Rayos (prednisone) for a long time
    Detailed Rayos (prednisone) risks & warnings »
    Pregnancy

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    Cortisoneprednisone
    No alcohol related info.
    • Taking Rayos (prednisone) increases the risk of injury to your stomach. You should avoid drinking alcohol while taking this medicine because it can worsen stomach irritation. Tell your doctor right away if you experience stomach pain that does not go away or you get bloody/dark stools.
    Food
    Cortisoneprednisone
    No food related info.
    • Take Rayos (prednisone) in the morning with food to lower your chances of getting stomach upset and having trouble sleeping. For an evening dose, it is best to take the medicine at least 2 to 3 hours before bedtime.
    Kidneys and liver
    Cortisoneprednisone
    No kidneys and liver related info.
    • Rayos (prednisone) can cause high blood pressure, unexplained weight gain, and other changes in the way your kidneys work. If you have a history of heart failure, high blood pressure, or kidney problems, talk to your doctor first before using this medicine.
    Upsides and benefits
    Cortisoneprednisone
    Coming soon
    • Rayos (prednisone) effectively treats a variety of conditions involving the immune system.
    • Can help improve energy and stimulate your appetite.
    • Works quickly to provide relief for swelling, rash, asthma attacks, and pain.
    • Good long-term treatment option for autoimmune disorders.
    • Rayos (prednisone) is available in a generic form.
    Downsides and risks
    Cortisoneprednisone
    Coming soon
    • Rayos (prednisone) can cause unwanted side effects such as mood changes, trouble sleeping, and increase in blood pressure as well as blood sugar at higher doses.
    • Long-term use can cause problems to your skin, bones, eyes, and place you at a higher risk for infections.
    • If Rayos (prednisone) is used for more than 2 weeks, you will need to work with a doctor to taper off the medicine by gradually decreasing the dose.
    • Rayos (prednisone) can harm an unborn baby, so it's not a good option for pregnant women.
    Tips from our pharmacists for people taking the medication
    Cortisoneprednisone
    Coming soon
    • Take Rayos (prednisone) in the morning with food to lower your chances of getting stomach upset and having trouble sleeping. For an evening dose, it is best to take the medicine at least 2 to 3 hours before bedtime.
    • Rayos (prednisone) can increase your appetite, make your body retain more water, and cause changes to your mood.
    • Rayos (prednisone) can increase your blood pressure and blood sugar at higher doses. If you have high blood pressure or diabetes, it is important that you check your blood pressure and blood sugar regularly while taking this medicine.
    • If you need to take Rayos (prednisone) for longer than 2 weeks, you may need to gradually stop taking this medicine. Take it exactly as your doctor told you and do not stop suddenly.
    • Rayos (prednisone) can increase your chances of getting an infection. Call your doctor right away if you have a fever, chills, flu-like symptoms, cough, pain with passing urine, or a wound that will not heal.
    Learn more
    More about CortisoneSide effectsReviews & ratingsFDA package insert
    Have you used Cortisone?
    Worth itNot sureNot worth it
    More about prednisoneSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Rayos (prednisone)?
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