Compare Coumadin vs. Aspirin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coumadin
(Warfarin)

Aspirin

Prevents blood clots. Coumadin (Warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.Relieves pain, fever, and inflammation. Protects your heart and thins blood. A low dose of Aspirin (81mg) every day can protect your heart, but it's not the best medicine to take for pain, swelling, or fever.
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Reviews & ratings
Filter group. All currently selected
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5.15Coumadin
Reviews for Coumadin (Warfarin)
61%
of people (All ages) say Coumadin (Warfarin) is worth it
54%
say it works well
21%
say it's a big hassle
513 reviews
Have you used Coumadin (Warfarin)?
Worth itNot sureNot worth it
Reviews for Aspirin
76%
+15% vs. Coumadin (Warfarin)
41%
13% vs. Coumadin (Warfarin)
6%
+15% vs. Coumadin (Warfarin)
533 reviews
Have you used Aspirin?
Worth itNot sureNot worth it
Side effects
CoumadinAspirin

The Coumadin FDA package insert doesn’t have numbers about how common side effects are.

More about Coumadin side effects »

We haven’t found good data for Aspirin side effects.

FDA side effect reports for Aspirin »
How it works
CoumadinAspirin
Coumadin (Warfarin) prevents blood clots from forming. It doesn't break up clots that already exist. It can only stop new ones from forming or old ones from getting bigger.Aspirin is a salicylate and non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain. It also prevents blood platelets from forming clots, which thins your blood.
Type of medication
CoumadinAspirin
Anticoagulant
Vitamin K antagonist
Prescription only
Pain reliever
Salicylate
Anticoagulant
Anti-platelet
Over-the-counter
Available as
CoumadinAspirin
  • Pill
  • Pill
Used for (click to learn more)
CoumadinAspirin
Risk factors for serious side effects
CoumadinAspirin
  • Coumadin (Warfarin) dose too high
  • Age greater than 65 year
  • History of stomach bleeding
  • High blood pressure
  • Kidney or liver problems
Detailed risks & warnings »
  • Children 18 years or younger
  • Children recovering from viral infections
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking Aspirin, NSAIDs, or blood thinners
Detailed risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Interactions
CoumadinAspirin
  • A lot of other drugs and supplements interact with Coumadin (Warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
  • Coumadin (Warfarin) interacts with many drugs and supplements. This can increase your risk of bleeding or of developing a new blood clot. If you start a new medication or change your diet, let your doctor know so they can change your dose if necessary.
No interactions related info.
Food
CoumadinAspirin
No food related info.
  • Take with food to lower the chance of an upset stomach.
Pain
CoumadinAspirin
No pain related info.
  • Used in higher doses to relieve pain, swelling, and fever.
Upsides and benefits
CoumadinAspirin
  • Coumadin (Warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (Warfarin), your doctor can give you another drug that reverses Coumadin (Warfarin)'s effects.
  • Coumadin (Warfarin) comes in numerous strengths.
  • Coumadin (Warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
  • When taking low doses (81 mg) every day, Aspirin provides protection for your heart and prevents heart attacks and stroke.
  • Used in higher doses to relieve pain, swelling, and fever.
  • Available over-the-counter in drugstores by itself and in combination with other cold and flu medications.
Downsides and risks
CoumadinAspirin
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (Warfarin) is working correctly.
  • Your daily dose of Coumadin (Warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (Warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
  • Not a preferred medication for treating pain, swelling, or fever due to its high risk of bleeding.
  • NSAIDs (like ibuprofen and naproxen) and acetaminophen (Tylenol) are better for treating pain and fever thank Aspirin.
  • Aspirin raises your risk of bleeding, especially when used with other blood thinner medications like warfarin (Coumadin).
  • Studies show that using higher doses of Aspirin (162 mg or more) every day raises your risk of stomach bleeding and doesn't provide any additional heart protection.
Tips from our pharmacists for people taking the medication
CoumadinAspirin
  • Prevents clots from forming or getting bigger. It doesn't break up clots that already exist.
  • Take Coumadin (Warfarin) exactly as your doctor tells you.
  • Once you're taking Coumadin (Warfarin), it'll take longer for your body to heal if you get cut or bruised. Call your doctor if you notice any unusual bleeding or bruising.
  • Carry a list of your medications with you or wear a medical bracelet that says you're on Coumadin (Warfarin) in case you have a medical emergency.
  • Your doctor will check your blood regularly for the first few months that you're taking Coumadin (Warfarin).
  • To get the best results, don't fall behind on taking your other medicines and eat the same amount of vegetables each day.
  • Using low doses (81mg) of Aspirin every day can lower your risk of heart attack and stroke, but it isn't good for everyone. Only take Aspirin daily if your doctor recommends it.
  • Higher Aspirin doses can be used to treat occasional pain, swelling, and fever. Using ibuprofen or acetaminophen (Tylenol) instead can lower your risk of serious bleeding.
  • Take with food to lower the chance of an upset stomach.
  • Don't use for kids younger than 18 years old.
  • Stop taking this right away and tell your doctor if you have ringing in your ears, unusual bleeding, or nausea or vomiting that doesn't go away.
Learn more
More about CoumadinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Coumadin (Warfarin)?
Worth itNot sureNot worth it
More about AspirinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Aspirin?
Worth itNot sureNot worth it