Compare Coumadin vs. Pradaxa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coumadin
(warfarin)

Pradaxa
(dabigatran)

Prevents blood clots. Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.Prevents blood clots. Pradaxa (Dabigatran) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. It can be expensive and there's no way to reverse the medication's effects.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for
Prices and coupon for 30 (5mg) tablets of warfarin
Coupons for
Prices and coupon for 1 (60 capsules of 150mg) dose pack of dabigatran
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.15Coumadin
Reviews for Coumadin (warfarin)
61%
of people (All ages) say Coumadin (warfarin) is worth it
54%
say it works well
21%
say it's a big hassle
513 reviews
Have you used Coumadin (warfarin)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Pradaxa (dabigatran)?
Worth itNot sureNot worth it
Side effects
CoumadinPradaxa

The Coumadin FDA package insert doesn’t have numbers about how common side effects are.

More about Coumadin side effects »
  • Gi side effect 35%
  • Any side effect 21%
  • Any bleed 20%
  • Indigestion 8%
  • Major gastrointestinal bleed 6%
  • Gi bleed 3%
  • Major bleed 3%
  • Gastritis-like symptoms 3%
  • Gastrointestinal bleed 2%
  • Life-threatening bleed 2%
More Pradaxa side effects »
How it works
CoumadinPradaxa
Coumadin (warfarin) prevents blood clots from forming. It doesn't break up clots that already exist. It can only stop new ones from forming or old ones from getting bigger.Pradaxa (Dabigatran) is an anticoagulant that stops the formation of blood clots.
Type of medication
CoumadinPradaxa
Prescription only
Prescription only
Available as
CoumadinPradaxa
  • Pill
  • Pill
Used for
CoumadinPradaxa
Risk factors for serious side effects
CoumadinPradaxa
  • Coumadin (warfarin) dose too high
  • Age greater than 65 year
  • History of stomach bleeding
  • High blood pressure
  • Kidney or liver problems
  • Drug interactions
  • Change in lifestyle or diet
  • Alcohol use
  • Certain genetic factors
  • Women of childbearing age
      Detailed Coumadin (warfarin) risks & warnings »
      • Stopping Pradaxa (Dabigatran) too soon
      • Spinal tap
      • Anesthesia along the spine (epidural anesthesia)
      • Taking NSAIDs, aspirin, or other blood-thinning medicines
      • Drug interactions
      • Taking with NSAIDs, aspirin, or other blood-thinning medicines
        • Artificial heart valve
        Detailed Pradaxa (dabigatran) risks & warnings »
        Pregnancy

        Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Interactions
        CoumadinPradaxa
        • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
        • Coumadin (warfarin) interacts with many drugs and supplements. This can increase your risk of bleeding or of developing a new blood clot. If you start a new medication or change your diet, let your doctor know so they can change your dose if necessary.
        No interactions related info.
        Upsides and benefits
        CoumadinPradaxa
        • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
        • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
        • Coumadin (warfarin) comes in numerous strengths.
        • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
        • Clinical studies have shown that the risk of stroke and blood clots is lower than with warfarin, another popular "blood thinner" (anticoagulant).
        • Doesn't require regular blood tests or frequent dose changes.
        • In studies comparing Pradaxa (Dabigatran) to other "blood thinners", it worked just as well in preventing strokes and was better in lowering the risk of bleeding.
        Downsides and risks
        CoumadinPradaxa
        • Raises your risk of bleeding and bruising.
        • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
        • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
        • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
        • Not available as generic.
        • There are no antidotes to stop bleeding caused by taking too much Pradaxa (Dabigatran).
        • Can't take during pregnancy.
        Tips from our pharmacists for people taking the medication
        CoumadinPradaxa
        • Prevents clots from forming or getting bigger. It doesn't break up clots that already exist.
        • Take Coumadin (warfarin) exactly as your doctor tells you.
        • Once you're taking Coumadin (warfarin), it'll take longer for your body to heal if you get cut or bruised. Call your doctor if you notice any unusual bleeding or bruising.
        • Carry a list of your medications with you or wear a medical bracelet that says you're on Coumadin (warfarin) in case you have a medical emergency.
        • Your doctor will check your blood regularly for the first few months that you're taking Coumadin (warfarin).
        • To get the best results, don't fall behind on taking your other medicines and eat the same amount of vegetables each day.
        • Pradaxa (Dabigatran) is an anticoagulant, so it's important not to miss a dose. Don't stop taking this medication without talking to your doctor first.
        • When taking Pradaxa (Dabigatran), you can bleed more easily, so use a soft toothbrush and an electric razor to avoid cutting yourself.
        • Take this exactly as your doctor or pharmacist tells you to.
        • Take with a full glass of water. Swallow the capsule whole. Don't chew, break, or open the capsule.
        Learn more
        More about CoumadinSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Coumadin (warfarin)?
        Worth itNot sureNot worth it
        More about PradaxaSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Pradaxa (dabigatran)?
        Worth itNot sureNot worth it