Compare Crestor vs. Atorvastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Crestor
(Rosuvastatin)

Lipitor
(Atorvastatin)

Lowers cholesterol. Crestor (Rosuvastatin) is one of the most effective statins to improve cholesterol, but the brand name medication is expensive. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.Lowers cholesterol. Lipitor (Atorvastatin) improves your cholesterol levels and is a common first treatment for people with high cholesterol or heart disease.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.02Crestor
Reviews for Crestor (Rosuvastatin)
60%
of people (All ages) say Crestor (Rosuvastatin) is worth it
47%
say it works well
15%
say it's a big hassle
751 reviews
Have you used Crestor (Rosuvastatin)?
Worth itNot sureNot worth it
Reviews for Lipitor (Atorvastatin)
63%
+3% better vs. Crestor (Rosuvastatin)
51%
+4% better vs. Crestor (Rosuvastatin)
13%
+2% better vs. Crestor (Rosuvastatin)
1377 reviews
Have you used Lipitor (Atorvastatin)?
Worth itNot sureNot worth it
Side effects
CrestorAtorvastatin
  • Headache 1%
  • Nausea 1%
  • Muscle pain 2%
  • Joint pain 1%
  • Diabetes mellitus 1%
  • Dizziness 1%
More Crestor side effects »
  • Diarrhea 1%
  • Indigestion 1%
  • Muscle spasms 1%
  • Muscle pain 1%
More Atorvastatin side effects »
How it works
CrestorAtorvastatin
Crestor (Rosuvastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Lipitor (Atorvastatin) is a cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
Type of medication
CrestorAtorvastatin
Prescription only
Prescription only
Available as
CrestorAtorvastatin
  • Pill
  • Pill
Used for
CrestorAtorvastatin
Risk factors for serious side effects
CrestorAtorvastatin
    • Heavy alcohol use
    • Prior history of chronic liver disease
    • Pregnancy
    Detailed Crestor (Rosuvastatin) risks & warnings »
      • Heavy alcohol use
      • Prior history of chronic liver disease
      • Pregnancy
      • History of hemorrhagic strokes
        Detailed Lipitor (Atorvastatin) risks & warnings »
        Pregnancy

        Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

        Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

        Alcohol
        CrestorAtorvastatin
        • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
        • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
        Kidneys and liver
        CrestorAtorvastatin
        • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
        • People on Crestor (Rosuvastatin) have reported muscle pain which may lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain or weakness or fever and you don't know why.
        • Liver damage has been reported in people who take Crestor (Rosuvastatin). If you notice dark urine or yellowing of the eyes or skin, talk to your doctor. Your doctor may monitor your liver periodically.
        • Statins such as Lipitor (Atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
        • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (Atorvastatin).
        • People on Lipitor (Atorvastatin) have reported muscle pain, which may lead to muscle and kidney damage. This is more likely to happen if you're older and you're taking higher doses of Lipitor (Atorvastatin). If you suddenly feel muscle pain or weakness and you haven't been exercising, stop taking Lipitor (Atorvastatin) and talk to your doctor right away.
        • Liver damage has been reported in people who take Lipitor (Atorvastatin). If you notice dark urine or yellowing of your eyes or skin, talk to your doctor. Your doctor might run blood tests to check your liver.
        Pain
        CrestorAtorvastatin
        No pain related info.
        • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
        Upsides and benefits
        CrestorAtorvastatin
        • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
        • Slows down the buildup of fatty deposits in your blood vessels, otherwise known as hardening of the arteries.
        • In clinical studies, Crestor has the strongest effect on lowering "bad" cholesterol compared to other statins.
        • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
        • Lowers "bad" cholesterol (LDL) and triglycerides (fats), and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
        • Lipitor (Atorvastatin) can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
        • It's one of the strongest cholesterol-lowering statin medications.
        • Lipitor (Atorvastatin) is a good option for people who have high cholesterol and diabetes.
        • It's available as a generic drug and can be used in combination with other cholesterol lowering drugs.
        Downsides and risks
        CrestorAtorvastatin
        • Even with a generic available in 2016, can be expensive.
        • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
        • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
        • Not safe to use if you're pregnant.
        • Statins such as Lipitor (Atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
        • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
        • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (Atorvastatin).
        Tips from our pharmacists for people taking the medication
        CrestorAtorvastatin
        • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
        • Don't take antacids for at least 2 hours before and after taking this medicine.
        • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
        • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
        • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
        • Don't eat grapefruit or drink grapefruit juice while taking this medicine.
        • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
        • Also tell your doctor if you have dark urine or if you notice a yellow tint in your eyes or skin.
        • Lipitor (Atorvastatin) isn't safe to use if you're pregnant.
        Learn more
        More about CrestorSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Crestor (Rosuvastatin)?
        Worth itNot sureNot worth it
        More about AtorvastatinSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Lipitor (Atorvastatin)?
        Worth itNot sureNot worth it