Compare Crestor vs. Lovastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Crestor (rosuvastatin)

Prescription only

Mevacor (Lovastatin)

Prescription only
Lowers cholesterol.

Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It's also available as a generic.

3.7/ 5 average rating with 751 reviewsforCrestor
Lowers cholesterol.

Mevacor (Lovastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.

3.4/ 5 average rating with 89 reviewsforLovastatin
Upsides
  • It's a good first choice medicine for lowering cholesterol levels when diet and exercise aren't enough.
  • Slows down the buildup of fatty deposits in your blood vessels, otherwise known as a hardening of the arteries.
  • In clinical studies, Crestor (rosuvastatin) has the strongest effect on lowering "bad" cholesterol compared to other statins.
  • Can lower your risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Available as a generic drug.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
Downsides
  • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
  • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
  • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
  • Not the best choice for people who have very high cholesterol levels.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
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Reviews
751 reviews so far
60%
saidit'sworth it
47%
saiditworked well
15%
saidit'sa big hassle

Have you used Crestor (rosuvastatin)?

Leave a review
89 reviews so far
43%
saidit'sworth it
39%
saiditworked well
22%
saidit'sa big hassle

Have you used Mevacor (Lovastatin)?

Leave a review
Side effects
The Crestor (rosuvastatin) FDA package insert doesn’t have numbers about how common side effects are.
2possible side effects
  • Elevations of CK levels
    11%
  • Increase in serum transaminases
    2%
See more detailed side effects
Risks and risk factors
  • Elevated INR
    • Taking Coumadin (warfarin)
  • Muscle pain
    • Age 65 or older
    • Taking higher doses of Crestor (rosuvastatin)
  • Increased blood sugars
    • Diabetes
  • Liver damage
    • Heavy alcohol use
    • Prior history of chronic liver disease
  • Birth defects
    • Pregnancy
See more detailed risks and warnings
  • Muscle pain
    • Kidney disease
    • High dose of Mevacor (Lovastatin)
    • Combining with certain cholesterol-lowering drugs
    • Older age and female gender
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to fetus
    • Pregnancy
    • Breast feeding
  • Drug interactions
    • Taking with certain drugs that increase the dose of Mevacor (Lovastatin) in the body
  • Muscle weakness (autoimmune)
See more detailed risks and warnings
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Disclaimer: We don't provide medical advice. If you think you might have a medical emergency, call your doctor or 911 immediately.