Compare Crestor vs. Lovastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Crestor
(rosuvastatin)

Mevacor
(lovastatin)

Lowers cholesterol. Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It's also available as a generic.Lowers cholesterol. Mevacor (Lovastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.
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Coupons for Crestor
Best available price for 30 (10mg) tablets of crestor
Coupons for Lovastatin
Best available price for 30 (20mg) tablets of lovastatin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.02Crestor
Reviews for Crestor
60%
of people (All ages) say Crestor is worth it
47%
say it works well
15%
say it's a big hassle
751 reviews
Have you used Crestor (rosuvastatin)?
Worth itNot sureNot worth it
Reviews for Lovastatin
43%
+17% better vs. Crestor
39%
+8% better vs. Crestor
22%
+7% better vs. Crestor
Have you used Mevacor (lovastatin)?
Worth itNot sureNot worth it
Side effects
CrestorLovastatin
  • Headache 1%
  • Nausea 1%
  • Muscle pain 2%
  • Joint pain 1%
  • Diabetes mellitus 1%
  • Dizziness 1%
More Crestor side effects »
  • Diarrhea 1%
  • Muscle pain 1%
  • Muscle weakness 1%
  • Elevations of ck levels 11%
More Lovastatin side effects »
How it works
CrestorLovastatin
Crestor (rosuvastatin) is a statin medication that changes the amount of cholesterol your body makes. It lowers "bad" cholesterol (LDL) and improves your "good" cholesterol (HDL) levels.Mevacor (Lovastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
Type of medication
CrestorLovastatin
Prescription onlyPrescription only
Available as
CrestorLovastatin
  • Pill
  • Pill
  • Extended release
Used for
CrestorLovastatin
Risk factors for serious side effects
CrestorLovastatin
  • Taking Coumadin (warfarin)
  • Age 65 or older
  • Taking higher doses of Crestor (rosuvastatin)
  • Diabetes
  • Heavy alcohol use
Detailed Crestor (rosuvastatin) risks & warnings »
  • Kidney disease
  • High dose of Mevacor (Lovastatin)
  • Combining with certain cholesterol-lowering drugs
  • Older age and female gender
  • Heavy alcohol use
Detailed Mevacor (lovastatin) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Interactions
CrestorLovastatin
No interactions related info.
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
Alcohol
CrestorLovastatin
  • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
  • Don't have more than 2 glasses of alcohol a day since Crestor (rosuvastatin) can cause liver damage.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
Food
CrestorLovastatin
No food related info.
  • Works best if you take it once a day after your evening meal.
Kidneys and liver
CrestorLovastatin
  • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
  • People on Crestor (rosuvastatin) have reported muscle pain which can lead to muscle or kidney damage. This is more likely to happen if you're older and if you're taking higher doses of Crestor (rosuvastatin). If you suddenly feel severe muscle pain or weakness and you haven't been exercising, stop taking Crestor (rosuvastatin) and talk to your doctor right away.
  • Crestor (rosuvastatin) can cause liver damage. If your urine is darker than normal or if you notice a yellow color in your eyes or skin, talk to your doctor. Your doctor may run some tests to see how your liver is working.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • There are rare cases of muscle damage leading to kidney failure in people taking Mevacor (Lovastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
  • There are reports of liver damage in people who take Mevacor (Lovastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
Pain
CrestorLovastatin
  • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
  • Call your doctor if you have sudden muscle pain, fever, or weakness.
  • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
Upsides and benefits
CrestorLovastatin
  • It's a good first choice medicine for lowering cholesterol levels when diet and exercise aren't enough.
  • Slows down the buildup of fatty deposits in your blood vessels, otherwise known as a hardening of the arteries.
  • In clinical studies, Crestor (rosuvastatin) has the strongest effect on lowering "bad" cholesterol compared to other statins.
  • Can lower your risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Available as a generic drug.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
Downsides and risks
CrestorLovastatin
  • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
  • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
  • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
  • Not the best choice for people who have very high cholesterol levels.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
Tips from our pharmacists for people taking the medication
CrestorLovastatin
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol levels.
  • Don't have more than 2 glasses of alcohol a day since Crestor (rosuvastatin) can cause liver damage.
  • Don't take antacids for at least 2 hours before and after taking Crestor (rosuvastatin).
  • Call your doctor if you have sudden muscle pain, fever, or weakness.
  • Let your doctor know if you have dark urine or a yellow color in your eyes or skin.
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Most people reach their target cholesterol levels in 4 to 6 weeks.
  • Works best if you take it once a day after your evening meal.
  • Avoid grapefruit and grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
Learn more
More about CrestorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Crestor (rosuvastatin)?
Worth itNot sureNot worth it
More about LovastatinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Mevacor (lovastatin)?
Worth itNot sureNot worth it