Compare Crestor vs. pravastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Crestor
(rosuvastatin)

pravastatin

Lowers cholesterol. Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It's also available as a generic.Lowers cholesterol. Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.02Crestor
Reviews for Crestor
60%
of people (All ages) say Crestor is worth it
47%
say it works well
15%
say it's a big hassle
751 reviews
Have you used Crestor (rosuvastatin)?
Worth itNot sureNot worth it
Reviews for pravastatin
54%
+6% better vs. Crestor
44%
+3% better vs. Crestor
19%
+4% better vs. Crestor
426 reviews
Have you used Pravachol (pravastatin)?
Worth itNot sureNot worth it
Side effects
Crestorpravastatin
  • Muscle pain 2%
  • Nausea 1%
  • Headache 1%
  • Diabetes mellitus 1%
  • Joint pain 1%
  • Dizziness 1%
More Crestor side effects »
  • Increased liver enzymes 1%
  • Rash 2%
  • Abdominal swelling 1%
  • Influenza 2%
  • Myalgia 2%
  • Bile duct disease 2%
  • Chest pain     2%
More pravastatin side effects »
How it works
Crestorpravastatin
Crestor (rosuvastatin) is a statin medication that changes the amount of cholesterol your body makes. It lowers "bad" cholesterol (LDL) and improves your "good" cholesterol (HDL) levels.Pravachol (pravastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
Type of medication
Crestorpravastatin
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
Crestorpravastatin
  • Pill
  • Pill
Used for
Crestorpravastatin
Risk factors for serious side effects
Crestorpravastatin
  • Taking Coumadin (warfarin)
  • Age 65 or older
  • Taking higher doses of Crestor (rosuvastatin)
  • Diabetes
  • Heavy alcohol use
Detailed Crestor (rosuvastatin) risks & warnings »
  • Kidney disease
  • An underactive thyroid
  • Over age 65
  • Female gender
  • Taking other medicines to lower your cholesterol
Detailed Pravachol (pravastatin) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Alcohol
Crestorpravastatin
  • Don't have more than 2 glasses of alcohol a day since Crestor (rosuvastatin) can cause liver damage.
  • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
No alcohol related info.
Kidneys and liver
Crestorpravastatin
  • People on Crestor (rosuvastatin) have reported muscle pain which can lead to muscle or kidney damage. This is more likely to happen if you're older and if you're taking higher doses of Crestor (rosuvastatin). If you suddenly feel severe muscle pain or weakness and you haven't been exercising, stop taking Crestor (rosuvastatin) and talk to your doctor right away.
  • Crestor (rosuvastatin) can cause liver damage. If your urine is darker than normal or if you notice a yellow color in your eyes or skin, talk to your doctor. Your doctor may run some tests to see how your liver is working.
  • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
Pain
Crestorpravastatin
  • Call your doctor if you have sudden muscle pain, fever, or weakness.
  • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
No pain related info.
Upsides and benefits
Crestorpravastatin
  • It's a good first choice medicine for lowering cholesterol levels when diet and exercise aren't enough.
  • Slows down the buildup of fatty deposits in your blood vessels, otherwise known as a hardening of the arteries.
  • In clinical studies, Crestor (rosuvastatin) has the strongest effect on lowering "bad" cholesterol compared to other statins.
  • Can lower your risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Available as a generic drug.
  • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • It's available as a generic.
Downsides and risks
Crestorpravastatin
  • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
  • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
  • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
  • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
  • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
Tips from our pharmacists for people taking the medication
Crestorpravastatin
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol levels.
  • Don't have more than 2 glasses of alcohol a day since Crestor (rosuvastatin) can cause liver damage.
  • Don't take antacids for at least 2 hours before and after taking Crestor (rosuvastatin).
  • Call your doctor if you have sudden muscle pain, fever, or weakness.
  • Let your doctor know if you have dark urine or a yellow color in your eyes or skin.
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Most people reach their target cholesterol levels in 4 to 6 weeks.
  • Don't eat grapefruit and drink grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Also let your doctor know if you notice dark urine or yellowing of your eyes or skin.
  • You'll need to stop taking Pravachol (pravastatin) if you get pregnant.
Learn more
More about CrestorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Crestor (rosuvastatin)?
Worth itNot sureNot worth it
More about pravastatinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Pravachol (pravastatin)?
Worth itNot sureNot worth it