Compare Crestor vs. pravastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Crestor (rosuvastatin)

Prescription only

Pravachol (pravastatin)

Prescription only
Lowers cholesterol.

Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It's also available as a generic.

3.7/ 5 average rating with 751 reviewsforCrestor
Lowers cholesterol.

Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.

3.5/ 5 average rating with 426 reviewsforpravastatin
Upsides
  • It's a good first choice medicine for lowering cholesterol levels when diet and exercise aren't enough.
  • Slows down the buildup of fatty deposits in your blood vessels, otherwise known as a hardening of the arteries.
  • In clinical studies, Crestor (rosuvastatin) has the strongest effect on lowering "bad" cholesterol compared to other statins.
  • Can lower your risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Available as a generic drug.
  • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • It's available as a generic.
Downsides
  • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
  • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
  • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
  • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
  • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
751 reviews so far
60%
saidit'sworth it
47%
saiditworked well
15%
saidit'sa big hassle

Have you used Crestor (rosuvastatin)?

Leave a review
426 reviews so far
54%
saidit'sworth it
44%
saiditworked well
19%
saidit'sa big hassle

Have you used Pravachol (pravastatin)?

Leave a review
Side effects
The Crestor (rosuvastatin) FDA package insert doesn’t have numbers about how common side effects are.
20possible side effects
  • Muscle, joint or ligament/tendon pain    
    10%
  • Nausea, vomiting    
    7%
  • Diarrhea    
    7%
  • Headache    
    6%
  • Upper respiratory infection    
    6%
  • Chest pain    
    5%
  • Rash
    5%
  • Dizziness
    4%
  • Stuffy nose
    4%
  • Muscle damage
    4%
  • Flatulence    
    3%
  • Indigestion, heartburn    
    3%
  • Fatigue    
    3%
  • Cough
    3%
  • Increased liver enzymes
    3%
  • Abdominal swelling
    2%
  • Influenza
    2%
  • Muscle pain
    2%
  • Sore throat
    2%
  • Bile duct disease
    2%
See more detailed side effects
Risks and risk factors
  • Elevated INR
    • Taking Coumadin (warfarin)
  • Muscle pain
    • Age 65 or older
    • Taking higher doses of Crestor (rosuvastatin)
  • Increased blood sugars
    • Diabetes
  • Liver damage
    • Heavy alcohol use
    • Prior history of chronic liver disease
  • Birth defects
    • Pregnancy
See more detailed risks and warnings
  • Muscle damage
    • Kidney disease
    • An underactive thyroid
    • Over age 65
    • Female gender
    • Taking other medicines to lower your cholesterol
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to fetus
    • Pregnancy
    • Breast feeding
  • Endocrine function
    • Spironolactone use
    • Cimetidine use
    • Ketoconazole use
See more detailed risks and warnings