Compare Crestor vs. Zetia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Crestor (rosuvastatin)

Prescription only

Zetia (ezetimibe)

Prescription only
Lowers cholesterol.

Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It's also available as a generic.

5.0/ 7 average rating with 751 reviewsforCrestor
Lowers cholesterol.

Zetia (ezetimibe) can improve your cholesterol and can be used as an alternative to statins.

4.4/ 7 average rating with 128 reviewsforZetia
Upsides
  • It's a good first choice medicine for lowering cholesterol levels when diet and exercise aren't enough.
  • Slows down the buildup of fatty deposits in your blood vessels, otherwise known as a hardening of the arteries.
  • In clinical studies, Crestor (rosuvastatin) has the strongest effect on lowering "bad" cholesterol compared to other statins.
  • Can lower your risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Available as a generic drug.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can be used with other medicines to improve cholesterol.
  • Available in a combination pill with simvastatin.
  • Available as a generic.
Downsides
  • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
  • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
  • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
  • Doesn't lower triglycerides (fats).
  • Hasn't been shown to lower the risk of heart attacks or heart disease.
  • By itself, it isn't as effective as statins for improving cholesterol.
Used for
Dosage forms
  • Pill
  • Pill
Price
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$14.45
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$26.45
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Reviews
751 
60%
think this treatment is worth it
47%
think this treatment works well
15%
think this treatment is a hassle

Have you used Crestor (rosuvastatin)?

Leave a review
128 
42%
think this treatment is worth it
34%
think this treatment works well
21%
think this treatment is a hassle

Have you used Zetia (ezetimibe)?

Leave a review
Side effects
The Crestor (rosuvastatin) FDA package insert doesn’t have numbers about how common side effects are.
8possible side effects
  • Diarrhea
    4%
  • Common cold
    4%
  • Sore throat
    4%
  • Sinus infection
    3%
  • Joint pain
    3%
  • Pain in arms and legs
    3%
  • Muscle pain
    3%
  • Abnormal liver tests
    3%
See more detailed side effects
Risks and warnings
  • Elevated INR

    Taking Coumadin (warfarin)

  • Muscle pain

    Age 65 or older

    ...and 1 more risk factors

  • Increased blood sugars

    Diabetes

  • Liver damage

    Heavy alcohol use

    ...and 1 more risk factors

  • Birth defects

    Pregnancy

See more detailed risks and warnings
  • Muscle pain

    Taking Zetia (ezetimibe) with statins

  • Abnormal liver blood tests

    Past history of liver disease

    ...and 1 more risk factors

See more detailed risks and warnings