Compare Cromolyn vs. Humira

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Intal (Cromolyn)

Prescription or OTC

Humira (adalimumab)

Prescription only
Relieves nasal allergy symptoms.

Intal (Cromolyn) is a good option to relieve nasal allergy symptoms when antihistamines aren't working. Good choice for pregnant women.

Calms down the immune system.

Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects.

3.6/ 5 average rating with 182 reviewsforHumira
Upsides
  • Treats nasal allergy symptoms.
  • Most people don't have many side effects since it works in the nose and doesn't affect the rest of your body.
  • It's a good option for pregnant women. Can also be used for kids 2 years and older.
  • Doesn't make you drowsy or dizzy.
  • No prescription is needed.
  • Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
  • You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
  • Humira (adalimumab) treats many different autoimmune conditions.
  • Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
Downsides
  • Needs to be used regularly for at least a week to see any good effects.
  • Can have an unpleasant smell or taste.
  • Can cause headaches, or burning and stinging in your nose.
  • Not first-choice treatment for rheumatoid arthritis.
  • Humira (adalimumab) is an injection and not an oral medication.
  • Humira (adalimumab) is expensive because there's no generic available yet.
  • Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
  • You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
  • Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
Used for
Dosage forms
  • Nasal spray
  • Injection
Price
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Reviews
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182 reviews so far
60%
saidit'sworth it
51%
saiditworked well
26%
saidit'sa big hassle

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Side effects
The Intal (Cromolyn) FDA package insert doesn’t have numbers about how common side effects are.
14possible side effects
  • Upper airway infection
    17%
  • Headache
    12%
  • Rash
    12%
  • Sinus infection
    11%
  • Nausea
    9%
  • Injection site reactions
    8%
  • Urinary tract infection
    8%
  • Flu syndrome
    7%
  • Stomach pain
    7%
  • High cholesterol
    7%
  • Back pain
    6%
  • Blood in urine
    5%
  • Abnormal liver tests
    5%
  • High blood pressure
    5%
See more detailed side effects
Risks and risk factors
No information currently available
  • Serious infections
    • Taking other immunosuppressant medications such as Kineret or Orencia
    • Age 65 or older
    • Active, chronic, or recurrent infection
    • Comorbidities
  • Cancers
    • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Humira (adalimumab)
    • History of malignancy
    • Adolescent age
    • COPD with significant smoking history
  • Serious allergic reactions
  • Heart problems
    • History of heart failure
  • Nervous system effects
    • Preexisting or recently acquired neurologic condition
  • Lower blood cell counts
See more detailed risks and warnings