Compare Cromolyn vs. Humira

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Intal
(cromolyn)

Humira
(adalimumab)

Relieves nasal allergy symptoms. Intal (Cromolyn) is a good option to relieve nasal allergy symptoms when antihistamines aren't working. Good choice for pregnant women.Calms down the immune system. Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects.
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Prices and coupon for 1 (10ml of 4%) eye dropper of cromolyn
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Prices and coupon for 1 (2 pens of 40mg/0.8ml) carton of adalimumab
Reviews & ratings
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Have you used Intal (cromolyn)?
Worth itNot sureNot worth it
Reviews for Humira (adalimumab)
60%
+60% better vs. Intal (cromolyn)
51%
+51% better vs. Intal (cromolyn)
26%
-26% worse vs. Intal (cromolyn)
182 reviews
Have you used Humira (adalimumab)?
Worth itNot sureNot worth it
Side effects
CromolynHumira

We haven’t found good data for Cromolyn side effects.

FDA side effect reports for Cromolyn »
  • Upper airway infection 4%
  • Rash 6%
  • Headache 4%
  • Sinus infection 2%
  • Nausea 1%
  • Injection site reactions 7%
  • Urinary tract infection 3%
  • Flu syndrome 1%
  • Stomach pain 3%
  • High cholesterol 2%
More Humira side effects »
How it works
CromolynHumira
Intal (Cromolyn) is a mast-cell stabilizer nasal spray that prevents and treats seasonal allergies.Humira (adalimumab) is a TNF blocker which stops inflammation.
Type of medication
CromolynHumira
Prescription or OTC
Prescription only
Available as
CromolynHumira
  • Nasal spray
  • Injection
Used for
CromolynHumira
Risk factors for serious side effects
CromolynHumira
Coming soon.
  • Taking other immunosuppressant medications such as Kineret or Orencia
  • Age 65 or older
  • Active, chronic, or recurrent infection
  • Comorbidities
  • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Humira (adalimumab)
  • History of malignancy
  • Adolescent age
  • COPD with significant smoking history
    • History of heart failure
    • Preexisting or recently acquired neurologic condition
      Detailed Humira (adalimumab) risks & warnings »
      Pregnancy

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Sleep
      CromolynHumira
      • Doesn't make you drowsy or dizzy.
      No sleep related info.
      Upsides and benefits
      CromolynHumira
      • Treats nasal allergy symptoms.
      • Most people don't have many side effects since it works in the nose and doesn't affect the rest of your body.
      • It's a good option for pregnant women. Can also be used for kids 2 years and older.
      • Doesn't make you drowsy or dizzy.
      • No prescription is needed.
      • Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
      • You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
      • Humira (adalimumab) treats many different autoimmune conditions.
      • Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
      Downsides and risks
      CromolynHumira
      • Needs to be used regularly for at least a week to see any good effects.
      • Can have an unpleasant smell or taste.
      • Can cause headaches, or burning and stinging in your nose.
      • Not first-choice treatment for rheumatoid arthritis.
      • Humira (adalimumab) is an injection and not an oral medication.
      • Humira (adalimumab) is expensive because there's no generic available yet.
      • Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
      • You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
      • Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
      Tips from our pharmacists for people taking the medication
      CromolynHumira
      • Works best when used one week before exposure to allergens. It takes about 1 to 2 weeks until you feel the full effects.
      • Check with your doctor or pharmacist to make sure you know how to use this nose spray. Don't use more than recommended.
      • Shake the spray gently and clear your nose before each use.
      • Before using it for the first time, prime the spray pump until you see a fine mist.
      • Breathe in slowly as you're spraying. Wait a few minutes before blowing your nose if needed.
      • Humira (adalimumab) is a medication that's injected under the skin. Your doctor can give you your first dose, then you can inject yourself at home once you feel comfortable doing so on your own.
      • Humira (adalimumab) lowers your ability to fight infections, so it's important to let your doctor know if you have a fever, cough, or flu-like symptoms.
      • Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
      • Each time you use Humira (adalimumab), it's important to rotate the sites you chose to inject it in. Don't inject Humira (adalimumab) into skin that's red, bruised, or irritated.
      • As with all injection medicines, store securely away from children and throw away used syringes in an FDA-approved sharps disposal container, and not in the trash.
      Learn more
      More about CromolynSide effectsAlternativesFDA package insert
      Have you used Intal (cromolyn)?
      Worth itNot sureNot worth it
      More about HumiraSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Humira (adalimumab)?
      Worth itNot sureNot worth it