Compare cromolyn vs. Sulfasalazine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Intal
(Cromolyn)

Azulfidine
(Sulfasalazine)

Relieves nasal allergy symptoms. Intal (Cromolyn) is a good option to relieve nasal allergy symptoms when antihistamines aren't working. Good choice for pregnant women.Reduces inflammation. Azulfidine (Sulfasalazine) is used for moderate to severe inflammatory bowel conditions, and with other meds for treating rheumatoid arthritis.
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Reviews & ratings
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Side effects
cromolynSulfasalazine

We haven’t found good data for cromolyn side effects.

FDA side effect reports for cromolyn »

We haven’t found good data for Sulfasalazine side effects.

FDA side effect reports for Sulfasalazine »
How it works
cromolynSulfasalazine
Intal (Cromolyn) is a mast-cell stabilizer nasal spray that prevents and treats seasonal allergies.Azulfidine (Sulfasalazine) is an anti-inflammatory drug that reduces inflammation and pain. It treats inflammatory bowel diseases and rheumatoid arthritis.
Type of medication
cromolynSulfasalazine
Mast cell stabilizerPrescription or OTC
Immunosuppressant
Immunomodulator
Antirheumatic
Biological response modifier
Prescription only
Available as
cromolynSulfasalazine
  • Nasal spray
  • Pill
  • Extended release
Used for (click to learn more)
cromolynSulfasalazine
Risk factors for serious side effects
cromolynSulfasalazine
Coming soon.
          Detailed Azulfidine (Sulfasalazine) risks & warnings »
          Pregnancy category
          cromolynSulfasalazine
          BFDA pregnancy category (Probably safe)

          Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

          See the FDA package insert
          BFDA pregnancy category (Probably safe)

          Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          No specific food-related info.
          • Swallow tablets whole, and take after a meal with a full glass of water.
          Kidneys and liver
          No specific kidneys and liver-related info.
          • Azulfidine (Sulfasalazine) isn't a good option if you have kidney or liver disease.
          • Complete blood counts should be done before starting Azulfidine (Sulfasalazine) and every other week during the first three months of treatment. Since kidney damage can occur, you'll need a urinalysis and an assessment of your kidney function periodically during treatment.
          • Severe hypersensitivity reactions can include internal organ involvement, such as hepatitis (liver), nephritis (kidney), myocarditis (heart), blood abnormalities, or pneumonitis (lungs).
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          • Doesn't make you drowsy or dizzy.
          No specific sleep-related info.
          Weight
          No specific weight-related info.No specific weight-related info.
          Upsides and benefits
          cromolynSulfasalazine
          • Treats nasal allergy symptoms.
          • Most people don't have many side effects since it works in the nose and doesn't affect the rest of your body.
          • It's a good option for pregnant women. Can also be used for kids 2 years and older.
          • Doesn't make you drowsy or dizzy.
          • No prescription is needed.
          • When taken consistently, Azulfidine (Sulfasalazine) can control your symptoms of ulcerative colitis and other bowel diseases.
          • Azulfidine (Sulfasalazine) is usually used in combination with other medications to control rheumatoid arthritis.
          Downsides and risks
          cromolynSulfasalazine
          • Needs to be used regularly for at least a week to see any good effects.
          • Can have an unpleasant smell or taste.
          • Can cause headaches, or burning and stinging in your nose.
          • You need to have blood tests every 3 months when taking Azulfidine (Sulfasalazine).
          • Azulfidine (Sulfasalazine) isn't a good option if you have kidney or liver disease.
          • Can't take Azulfidine (Sulfasalazine) if you are allergic to aspirin or sulfa medications.
          • Azulfidine (Sulfasalazine) shouldn't be used if you are breastfeeding.
          Tips from our pharmacists for people taking the medication
          cromolynSulfasalazine
          • Works best when used one week before exposure to allergens. It takes about 1 to 2 weeks until you feel the full effects.
          • Check with your doctor or pharmacist to make sure you know how to use this nose spray. Don't use more than recommended.
          • Shake the spray gently and clear your nose before each use.
          • Before using it for the first time, prime the spray pump until you see a fine mist.
          • Breathe in slowly as you're spraying. Wait a few minutes before blowing your nose if needed.
          • Don't use if you are allergic to sulfa drugs or aspirin.
          • Swallow tablets whole, and take after a meal with a full glass of water.
          • Drink at least six glasses of water daily while on this.
          • Continue to take Azulfidine (Sulfasalazine) even once you feel better.
          • Read the information that come with your medication in the drugstore since there are many conditions you should be aware of before taking Azulfidine (Sulfasalazine).
          • Can cause an orange color in your urine or skin.
          Learn more
          More about cromolynSide effectsAlternativesFDA package insert
          More about SulfasalazineSide effectsReviews & ratingsAlternativesFDA package insert