Compare cyclophosphamide vs. Humira
Head-to-head comparisons of medication uses, side effects, ratings, and more.
As with all chemotherapy, Cytoxan (cyclophosphamide) has many side effects but is also very effective against different cancers.
Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects.
- Effective when used in combination with other anticancer agents or by itself against blood cancers and a kidney disease known as minimal change nephrotic syndrome.
- Cytoxan (cyclophosphamide) is one of the most well-known medications for cancer, so doctors know what to expect.
- Available in generic and in both a pill or as an injection.
- Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
- You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
- Humira (adalimumab) treats many different autoimmune conditions.
- Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
- Cytoxan (cyclophosphamide) can seriously damage the kidneys.
- Cytoxan (cyclophosphamide) can cause many different side effects throughout the body.
- Cytoxan (cyclophosphamide) is more likely to cause nausea and vomiting compared to other chemotherapy drugs.
- Cytoxan (cyclophosphamide) can cause infertility.
- Not first-choice treatment for rheumatoid arthritis.
- Humira (adalimumab) is an injection and not an oral medication.
- Humira (adalimumab) is expensive because there's no generic available yet.
- Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
- You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
- Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
- Upper airway infection17%
- Sinus infection11%
- Injection site reactions8%
- Urinary tract infection8%
- Flu syndrome7%
- Stomach pain7%
- High cholesterol7%
- Kidney disease
...and 1 more risk factors
- Liver disease
Previous liver disease
...and 2 more risk factors
- Heart disease
Previous radiation to chest
...and 4 more risk factors
- Serious infections
Taking other immunosuppressant medications such as Kineret or Orencia
...and 3 more risk factors
Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Humira (adalimumab)
...and 3 more risk factors
- Heart problems
History of heart failure
- Nervous system effects
Preexisting or recently acquired neurologic condition