Compare cyclophosphamide vs. Imbruvica

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cytoxan
(cyclophosphamide)

Imbruvica
(ibrutinib)

Treats various cancers and kidney disorders. As with all chemotherapy, Cytoxan (cyclophosphamide) has many side effects but is also very effective against different cancers.Coming soon.
Reviews & ratings
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Have you used Cytoxan (cyclophosphamide)?
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Have you used Imbruvica (ibrutinib)?
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Side effects
cyclophosphamideImbruvica

The cyclophosphamide FDA package insert doesn’t have numbers about how common side effects are.

More about cyclophosphamide side effects »

We haven’t found good data for Imbruvica side effects.

FDA side effect reports for Imbruvica »
How it works
cyclophosphamideImbruvica
Cytoxan (cyclophosphamide) works by stopping cancer cells from multiplying.Coming soon.
Type of medication
cyclophosphamideImbruvica
Prescription only
Available as
cyclophosphamideImbruvica
  • Pill
  • Injection
  • Pill
Used for
cyclophosphamideImbruvica
  • Chronic Lymphoid Leukemia
Risk factors for serious side effects
cyclophosphamideImbruvica
  • Dehydration
  • Urinary tract infections
  • Previous liver disease
  • Previous radiation to abdomen
  • Poor prognosis
Detailed Cytoxan (cyclophosphamide) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Kidneys and liver
    cyclophosphamideImbruvica
    • Cytoxan (cyclophosphamide) can cause kidney or bladder problems or make you at risk of getting kidney infections. To stop this from happening, you should drink plenty of liquids and urinate often. If you have pink or red urine or pain on urination, tell your doctor right away.
    • Effective when used in combination with other anticancer agents or by itself against blood cancers and a kidney disease known as minimal change nephrotic syndrome.
    • Cytoxan (cyclophosphamide) can seriously damage the kidneys.
    No kidneys and liver related info.
    Weight
    cyclophosphamideImbruvica
    • Cytoxan (cyclophosphamide) can cause liver damage. You're more likely to have this if you're taking certain other chemotherapy drugs or getting radiation throughout your entire body. If you have sudden weight gain, swelling of your stomach, fluid build up in your abdomen, yellowing skin or eyes, dark urine or pale stools, talk to your doctor right away.
    No weight related info.
    Upsides and benefits
    cyclophosphamideImbruvica
    • Effective when used in combination with other anticancer agents or by itself against blood cancers and a kidney disease known as minimal change nephrotic syndrome.
    • Cytoxan (cyclophosphamide) is one of the most well-known medications for cancer, so doctors know what to expect.
    • Available in generic and in both a pill or as an injection.
    Coming soon
    Downsides and risks
    cyclophosphamideImbruvica
    • Cytoxan (cyclophosphamide) can seriously damage the kidneys.
    • Cytoxan (cyclophosphamide) can cause many different side effects throughout the body.
    • Cytoxan (cyclophosphamide) is more likely to cause nausea and vomiting compared to other chemotherapy drugs.
    • Cytoxan (cyclophosphamide) can cause infertility.
    Coming soon
    Tips from our pharmacists for people taking the medication
    cyclophosphamideImbruvica
    • This medication comes in an injection or pill. You and your doctor will decide what form is most appropriate for you.
    • Drink plenty of fluids to prevent urinary problems.
    • You should protect yourself and your sexual partners from getting pregnant while taking Cytoxan (cyclophosphamide) for at least 4 months if you're a male or a year if you're female.
    • You're more likely to get sick or heal slower while taking Cytoxan (cyclophosphamide). Talk to your doctor before getting any vaccines.
    • Talk to your doctor if you start having breathing problems that don't go away.
    Coming soon
    Learn more
    More about cyclophosphamideSide effectsAlternativesFDA package insert
    Have you used Cytoxan (cyclophosphamide)?
    Worth itNot sureNot worth it
    More about ImbruvicaSide effectsReviews & ratingsFDA package insert
    Have you used Imbruvica (ibrutinib)?
    Worth itNot sureNot worth it