Compare cyclophosphamide vs. Imbruvica

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats various cancers and kidney disorders.

As with all chemotherapy, Cytoxan (cyclophosphamide) has many side effects but is also very effective against different cancers.

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  • Effective when used in combination with other anticancer agents or by itself against blood cancers and a kidney disease known as minimal change nephrotic syndrome.
  • Cytoxan (cyclophosphamide) is one of the most well-known medications for cancer, so doctors know what to expect.
  • Available in generic and in both a pill or as an injection.
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  • Cytoxan (cyclophosphamide) can seriously damage the kidneys.
  • Cytoxan (cyclophosphamide) can cause many different side effects throughout the body.
  • Cytoxan (cyclophosphamide) is more likely to cause nausea and vomiting compared to other chemotherapy drugs.
  • Cytoxan (cyclophosphamide) can cause infertility.
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Used for
  • Chronic lymphoid leukemia
  • In patients who have received at least 1 prior therapy Chronic lymphoid leukemia
  • In patients with 17p chromosome deletion Mantle cell lymphoma
  • In previously treated patients
Dosage forms
  • Pill
  • Injection
  • Pill
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Side effects
The Cytoxan (cyclophosphamide) FDA package insert doesn’t have numbers about how common side effects are.
The Imbruvica (Ibrutinib) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Blood cell problems
  • Kidney disease
    • Dehydration
    • Urinary tract infections
  • Liver disease
    • Previous liver disease
    • Previous radiation to abdomen
    • Poor prognosis
  • Heart disease
    • Previous radiation to chest
    • High dose cyclophosphamide
    • Other medications that have heart side effects
    • Age over 65
    • Previous heart disease
  • Infertility and birth defects
  • Lung problems
See more detailed risks and warnings
No information currently available