Compare cyclophosphamide vs. Orencia
Head-to-head comparisons of medication uses, side effects, ratings, and more.
As with all chemotherapy, Cytoxan (cyclophosphamide) has many side effects but is also very effective against different cancers.
Orencia (abatacept) slows the progress of rheumatoid arthritis, but can also cause serious side effects.
- Effective when used in combination with other anticancer agents or by itself against blood cancers and a kidney disease known as minimal change nephrotic syndrome.
- Cytoxan (cyclophosphamide) is one of the most well-known medications for cancer, so doctors know what to expect.
- Available in generic and in both a pill or as an injection.
- In a 2-year study that used IV Orencia (abatacept) with methotrexate, more than half of the people had remission and the majority felt significantly better.
- Helps minimize joint damage, lowers symptoms, and prevents future problems. People taking Orencia (abatacept) had no new joint damage after two years.
- Taking Orencia (abatacept) allows RA patients to use less prednisone, a steroid that has many side effects.
- You can give yourself Orencia (abatacept) subcutaneously on your own at home rather than visiting a clinic or hospital.
- Available in a prefilled autoinjector for convenient use.
- Cytoxan (cyclophosphamide) can seriously damage the kidneys.
- Cytoxan (cyclophosphamide) can cause many different side effects throughout the body.
- Cytoxan (cyclophosphamide) is more likely to cause nausea and vomiting compared to other chemotherapy drugs.
- Cytoxan (cyclophosphamide) can cause infertility.
- Orencia (abatacept) can be costly.
- The IV infusion form of Orencia (abatacept) can cause a reaction, which ranges from a slight itching or warm feeling to more serious side effects such as low blood pressure and chest pain.
- The IV infusion form of Orencia (abatacept) contains maltose, a type of sugar, that can give false high blood sugar readings with certain types of blood sugar monitors on the day of Orencia (abatacept) infusion. The self-injection subcutaneous form does not contain maltose. Talk to your doctor if you have diabetes.
- If you need TNF inhibitors as part of your treatment, it is not recommended to take Orencia (abatacept). If you have COPD, you are at higher risk of side effects.
- Orencia (abatacept) lowers your ability to fight infection. Your risk can increase if you take medications that lower your immune system or have an active infection. You may need to get tested for tuberculosis before starting Orencia (abatacept).
- Rheumatoid Arthritis
- Polyarticular Juvenile Idiopathic Arthritis
- Common cold12%
- Back pain7%
- High blood pressure7%
- Urinary tract infection6%
- Pain in arms or legs3%
- Kidney disease
...and 1 more risk factors
- Liver disease
Previous liver disease
...and 2 more risk factors
- Heart disease
Previous radiation to chest
...and 4 more risk factors
- High risk of infections with TNF inhibitors
Using TNF inhibitors
- Immunosuppression and Infections
Taking immunosuppressive medications
...and 2 more risk factors
- More COPD side effects