Compare cyclophosphamide vs. Remicade

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Remicade (infliximab)

Prescription only
Treats various cancers and kidney disorders.

As with all chemotherapy, Cytoxan (cyclophosphamide) has many side effects but is also very effective against different cancers.

Calms down your immune system.

Remicade (infliximab) is an effective treatment for many autoimmune diseases, but you can have serious side effects.

4.0/ 5 average rating with 55 reviewsforRemicade
Upsides
  • Effective when used in combination with other anticancer agents or by itself against blood cancers and a kidney disease known as minimal change nephrotic syndrome.
  • Cytoxan (cyclophosphamide) is one of the most well-known medications for cancer, so doctors know what to expect.
  • Available in generic and in both a pill or as an injection.
  • People taking Remicade (infliximab) for ulcerative colitis, Crohn's disease, rheumatoid arthritis and other autoimmune conditions had more clinical response, clinical remission and symptom improvement compared to people who did not take Remicade (infliximab).
  • People who were also taking steroids for treatment were able to discontinue steroid use while taking Remicade (infliximab).
  • Remicade (infliximab) has almost two decades of clinical trial data and real-life experience with many people who have used it.
  • After the initial dosing, you only need to take Remicade (infliximab) every 6-8 weeks, depending on your condition.
  • Compared to other medications used to treat autoimmune conditions, Remicade (infliximab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
Downsides
  • Cytoxan (cyclophosphamide) can seriously damage the kidneys.
  • Cytoxan (cyclophosphamide) can cause many different side effects throughout the body.
  • Cytoxan (cyclophosphamide) is more likely to cause nausea and vomiting compared to other chemotherapy drugs.
  • Cytoxan (cyclophosphamide) can cause infertility.
  • You have to receive this medication at your doctor's office or clinic. You might need to be tested regularly for tuberculosis.
  • Remicade (infliximab) lowers your ability to fight infection and can cause serious illness. The risk is greater if you take other drugs that lower your immune system, or have a history of diabetes or tuberculosis.
  • Remicade (infliximab) can in some cases worsen symptoms of heart failure or neurologic conditions. People 65 years and older may have more side effects from this medication.
  • In rare cases, Remicade (infliximab) has been associated with cancers in children and adolescents.
  • No generic available, so it can be costly.
Used for
Dosage forms
  • Pill
  • Injection
  • Injection
Price
Lowest price
$20695.40
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Reviews
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55 reviews so far
76%
saidit'sworth it
62%
saiditworked well
15%
saidit'sa big hassle

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Side effects
The Cytoxan (cyclophosphamide) FDA package insert doesn’t have numbers about how common side effects are.
The Remicade (infliximab) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Blood cell problems
  • Kidney disease
    • Dehydration
    • Urinary tract infections
  • Liver disease
    • Previous liver disease
    • Previous radiation to abdomen
    • Poor prognosis
  • Heart disease
    • Previous radiation to chest
    • High dose cyclophosphamide
    • Other medications that have heart side effects
    • Age over 65
    • Previous heart disease
  • Infertility and birth defects
  • Lung problems
See more detailed risks and warnings
  • Serious infections
    • Taking other immunosuppressant drugs
    • Age 65 or older
    • Comorbidities
  • Cancer
    • Taking other immunosuppressant drugs
    • History of malignancy
  • Heart failure
    • History of heart failure
    • Receiving higher doses
  • Nervous system effects
    • History of nerve problems
  • Lower blood cell counts
    • Ongoing or history of blood problems
  • Liver injury
See more detailed risks and warnings