Compare Cyclosporine vs. Humira

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coming soon.

Neoral
(Cyclosporine)

Humira
(Adalimumab)

Coming soon.Calms down your immune system. Humira (Adalimumab) is very effective at calming down your immune system, but it's expensive, you have to take into account the hassle of injections and traveling with the medication.
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Reviews & ratings
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Have you used Neoral (Cyclosporine)?
Worth itNot sureNot worth it
Reviews for Humira (Adalimumab)
60%
40% vs. Neoral (Cyclosporine)
51%
+1% vs. Neoral (Cyclosporine)
26%
+24% vs. Neoral (Cyclosporine)
182 reviews
Have you used Humira (Adalimumab)?
Worth itNot sureNot worth it
Side effects
CyclosporineHumira

We haven’t found good data for Cyclosporine side effects.

FDA side effect reports for Cyclosporine »

The Humira FDA package insert doesn’t have numbers about how common side effects are.

More about Humira side effects »
How it works
CyclosporineHumira
Coming soon.Humira (Adalimumab) is a biologic response modifier. It works in the immune system to block a protein called TNF (tumor necrosis factor). Blocking TNF relieves symptoms and prevents disease progression.
Type of medication
CyclosporineHumira
Coming soon.
Immunosuppressant
Immunomodulator
Antirheumatic
Biological response modifier
Prescription only
Available as
CyclosporineHumira
  • Pill
  • Liquid
  • Injection
Used for (click to learn more)
CyclosporineHumira
  • Cardiac transplant rejection; Prophylaxis Liver transplant rejection; Prophylaxis Plaque psoriasis (Severe)
Risk factors for serious side effects
CyclosporineHumira
  • History of heart failure
  • Taking other immunosuppressant drugs
  • Age 60 or older
  • History of malignancy
  • History of neurologic condition
Detailed risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Upsides and benefits
CyclosporineHumira
Coming soon
  • Treats certain types of arthritis and gastrointestinal conditions caused by an overactive immune system.
  • Most people feel it's worth the hassle.
  • Once you've learned the correct way to use Humira, you can inject the medicine yourself without going to your doctor's office.
  • It's available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
  • It's an alternative for people with Crohn's disease who stopped getting better on other TNF-blockers or had side effects that made them switch.
Downsides and risks
CyclosporineHumira
Coming soon
  • It's an injection.
  • It's expensive because there's no generic available yet.
  • Humira lowers your ability to fight infection and can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
  • You're first dose of Humira will need to be given at your doctor's office. If you decide not to self-inject and don't have someone to do it for you, you'll need to continue to see your doctor for each dose.
  • You'll need to properly dispose of the needle, syringes, or Pen in a special (FDA-approved) sharps container.
  • Because it needs to be refrigerated until you use it, if you're traveling, you'll need to carry it in a cooler with an ice pack.
Tips from our pharmacists for people taking the medication
CyclosporineHumira
Coming soon
  • Humira (Adalimumab) is a medication that's injected under the skin (subcutaneous). Your doctor can give you your first dose, then let you self-inject it once so you learn how to do it correctly.
  • Humira (Adalimumab) lowers the your immune system's ability to fight infections, so it's important to let your doctor know if you come down with a fever, cough, or notice flu-like symptoms.
  • You'll need to have a TB test before you start using Humira (Adalimumab).
  • Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
  • Don't inject Humira (Adalimumab) into skin that's red, bruised, or irritated. Rotate your injection areas to avoid skin reactions.
  • As with all injection medicines, store away from children and throw used syringes away in a protective container, and not in the trash.
Learn more
More about CyclosporineSide effectsReviews & ratingsFDA package insert
Have you used Neoral (Cyclosporine)?
Worth itNot sureNot worth it
More about HumiraSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Humira (Adalimumab)?
Worth itNot sureNot worth it