Compare Cymbalta vs. Tegretol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cymbalta (duloxetine)

Prescription only

Tegretol (Carbamazepine)

Prescription only
Improves mood and relieves certain types of pain.

Cymbalta (duloxetine) is good for treating depression, anxiety, and some forms of chronic pain, but it is more likely than other antidepressants to cause problems if you drink alcohol or have high blood pressure.

4.8/ 7 average rating with 496 reviewsforCymbalta
Prevents seizures, stabilizes mood, and relieves nerve pain.

Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.

4.5/ 7 average rating with 61 reviewsforTegretol
Upsides
  • Cymbalta (duloxetine) may help relieve nerve pain from diabetes and other forms of chronic pain.
  • Cymbalta (duloxetine) has several uses, which may be good for people with multiple conditions.
  • Available as a generic, which is cheaper.
  • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
  • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
  • May be helpful in stabilizing mood for people with bipolar disorder.
Downsides
  • Cymbalta (duloxetine) may not be a good option if you're a heavy drinker, or have liver or kidney problems.
  • Cymbalta (duloxetine) can increase high blood pressure.
  • Like most antidepressants, Cymbalta (duloxetine) can cause higher risk of suicidal thoughts and behavior for people aged 24 and younger.
  • Interacts with many other medicines and supplements.
  • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
  • Can cause blurry vision, dizziness, and upset stomach.
  • Not safe to use if you're pregnant.
  • Requires routine blood tests to see how the medicine is affecting your body.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
Price
Lowest price near you
$16.25
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Lowest price near you
$32
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Reviews
496 
58%
think this treatment is worth it
49%
think this treatment works well
24%
think this treatment is a hassle

Have you used Cymbalta (duloxetine)?

Leave a review
61 
56%
think this treatment is worth it
43%
think this treatment works well
23%
think this treatment is a hassle

Have you used Tegretol (Carbamazepine)?

Leave a review
Side effects
10possible side effects
  • Nausea
    23%
  • Headache
    14%
  • Dry mouth
    13%
  • Drowsiness
    10%
  • Fatigue
    9%
  • Difficulty sleeping
    9%
  • Constipation
    9%
  • Dizziness
    9%
  • Diarrhea
    9%
  • Decreased appetite
    7%
See more detailed side effects
10possible side effects
  • Dizziness
    44%
  • Somnolence
    32%
  • Nausea
    28%
  • Vomiting
    18%
  • Ataxia
    15%
  • Constipation
    10%
  • Pruritus
    8%
  • Dry Mouth
    8%
  • Asthenia
    8%
  • Rash
    7%
See more detailed side effects
Risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Serotonin syndrome

    Taking tricyclic antidepressants, lithium, tramadol, fentanyl, amphetamines, certain headache medications (triptans), St. John's Wort

  • Withdrawal

    Stopping Cymbalta (duloxetine) abruptly

  • Increased bleeding

    Taking other blood-thinning drugs (including aspirin, NSAIDs such as Advil, warfarin)

  • Changes in blood pressure and risk of falls

    Elderly patients

    ...and 4 more risk factors

  • Bipolar disorder

    History of bipolar disorder

    ...and 1 more risk factors

See more detailed risks and warnings
  • Serious skin rash

    People also taking Depakote

    ...and 1 more risk factors

  • Suicidal thoughts or behavior

    History of depression

  • Serious allergic reactions

    European, Chinese, or Japanese ancestry

  • Mental changes due to low sodium

    Age 65 years or older

  • Withdrawal seizures

    Stopping Tegretol (Carbamazepine) suddenly

See more detailed risks and warnings