Compare Dalmane vs. desipramine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dalmane (flurazepam)

Prescription only

Norpramin (desipramine)

Prescription only
Helps you fall asleep.

Dalmane (flurazepam) helps you fall asleep, but its effect can carry over to the next day and be addictive.

Stabilizes your mood.

Norpramin (desipramine) is not a first choice for treating depression because of its effects on the heart, but it can be good if other medicines haven't worked.

Upsides
  • Dalmane (flurazepam) works 15-30 minutes after taking it.
  • Dalmane (flurazepam) is available in generic.
  • Norpramin (desipramine) is available in generic and in many different strengths, so the dose can be more customized.
  • Norpramin (desipramine) has fewer side effects than similar tricyclic antidepressants.
Downsides
  • Can make you feel sleepy and unable to concentrate the next day. This hangover effect is especially worse for women and elderly.
  • Should only be used short-term because it can be addicting.
  • Can cause sleep-walking or other sleep-related activities that you may not remember doing the next day.
  • Norpramin (desipramine) isn't recommended if you or your family has heart disease, seizures, or glaucoma.
  • Norpramin (desipramine) isn't a first choice for depression because it has more side effects than other antidepressants.
  • In some people, Norpramin (desipramine) can make you sleepy. In other people, Norpramin (desipramine) can keep you awake.
  • If you have diabetes, Norpramin (desipramine) can make your blood sugar go up.
  • Not recommended in children under 12 years of age.
Used for
Dosage forms
  • Capsule
  • Pill
Price
No pricing information available
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Reviews
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Side effects
The Dalmane (flurazepam) FDA package insert doesn’t have numbers about how common side effects are.
The Norpramin (desipramine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Behavior changes
    • Alcohol
    • Taking narcotics, tranquilizers or antihistamines
  • Allergic reactions
  • Hangover effect
    • Women
    • Over age 65
  • Abuse and addiction
See more detailed risks and warnings
  • Higher risk of suicide
    • People under age 24
  • Possible bipolar disorder
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
  • Changes to the heartbeat
    • History of heart disease
  • Higher risk for seizures
    • History of seizures
    • History of brain damage or alcohol withdrawal
See more detailed risks and warnings