Compare Dantrium vs. Myrbetriq

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dantrium
(dantrolene)

Myrbetriq
(mirabegron)

Relaxes your muscles. Dantrium (dantrolene) effectively treats malignant hyperthermia (increased temperature and muscle contractions when receiving anesthesia) and is the only medicine used to treat the condition. Dantrium (dantrolene) is not a first-choice treatment for general muscle spasms because it can damage your liver.Treats overactive bladder. Myrbetriq (mirabegron) is a good treatment for overactive bladder with the least chance for dry mouth and constipation, but talk to your doctor if you have high blood pressure.
Reviews & ratings
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Have you used Dantrium (dantrolene)?
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Have you used Myrbetriq (mirabegron)?
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Side effects
DantriumMyrbetriq

The Dantrium FDA package insert doesn’t have numbers about how common side effects are.

More about Dantrium side effects »
  • High blood pressure 3%
  • Common cold symptoms 1%
  • Urinary tract infection 2%
  • Constipation 1%
  • Joint pain 1%
  • Rapid heart beat 1%
More Myrbetriq side effects »
How it works
DantriumMyrbetriq
Dantrium (dantrolene) stops spasms and relaxes muscle cells by interfering with the release of calcium inside muscle cells.Myrbetriq (mirabegron) is a beta-3 receptor agonist. It activates the receptor in your bladder, causing the bladder muscles to relax. This allows you to hold more urine and go to the bathroom less often.
Type of medication
DantriumMyrbetriq
Prescription onlyPrescription only
Available as
DantriumMyrbetriq
  • Pill
  • Injection
  • Extended release
Used for
DantriumMyrbetriq
  • Malignant Hyperthermia
Risk factors for serious side effects
DantriumMyrbetriq
  • Taking 800 mg or more Dantrium (dantrolene) per day
  • Women
  • Over 35 years old
  • Elderly
  • History of liver disease or dysfunction
Detailed Dantrium (dantrolene) risks & warnings »
  • Untreated high blood pressure
  • Bladder outlet obstruction
Detailed Myrbetriq (mirabegron) risks & warnings »
Pregnancy
Food
DantriumMyrbetriq
No food related info.
  • You can take Myrbetriq (mirabegron) with or without food. If it upsets your stomach, take it with food.
Kidneys and liver
DantriumMyrbetriq
No kidneys and liver related info.
  • Not recommended if you have severe liver or kidney disease.
Sleep
DantriumMyrbetriq
  • Taking Dantrium (dantrolene) may make you feel dizzy or sleepy for the first few days, especially if you drink alcohol or take recreational drugs. Avoid driving or other activities requiring concentration until you know how your body responds to the medication. Your body should adjust to the medicine. Talk to your doctor or pharmacist if these symptoms bother you.
  • Dantrium (dantrolene) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
  • Myrbetriq (mirabegron) causes less drowsiness and constipation than other medicines for overactive bladder.
Upsides and benefits
DantriumMyrbetriq
  • Dantrium (dantrolene) effectively treats malignant hyperthermia.
  • Can be used for muscle spasticity if other medications haven't worked.
  • Available as generic.
  • Myrbetriq (mirabegron) helps you to have better control over your urination.
  • Myrbetriq (mirabegron) causes less drowsiness and constipation than other medicines for overactive bladder.
  • May be used if you have glaucoma.
  • Myrbetriq (mirabegron) may be safer to use if you are over 65 years old.
Downsides and risks
DantriumMyrbetriq
  • Not a first-choice treatment for muscle spasms because it can cause liver damage.
  • Can cause dizziness, sleepiness, and sometimes severe diarrhea.
  • Needs routine blood tests since it can injure your liver.
  • Dose needs to be increased slowly to minimize side effects.
  • Myrbetriq (mirabegron) might raise your blood pressure.
  • If you have an obstruction in your bladder, Myrbetriq (mirabegron) might make you retain more urine.
  • Myrbetriq (mirabegron) may be very expensive depending on your insurance.
  • Not recommended if you have severe liver or kidney disease.
Tips from our pharmacists for people taking the medication
DantriumMyrbetriq
  • Dantrium (dantrolene) can worsen liver function.You may need to have your blood checked regularly before starting Dantrium (dantrolene) and while you're on it.
  • Dantrium (dantrolene) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
  • Dantrium (dantrolene) can cause diarrhea, but it usually goes away within the first few weeks. If it doesn't, talk to your doctor.
  • May make your skin sensitive to the sun. Wear sunblock and avoid prolonged exposure to sunlight while on Dantrium (dantrolene).
  • Myrbetriq (mirabegron) is a long-acting medicine. Do not crush, break or chew it.
  • Drink enough water to keep hydrated. Not drinking enough water on hot days can increase your chances of dehydration or heat stroke.
  • You can take Myrbetriq (mirabegron) with or without food. If it upsets your stomach, take it with food.
  • Drinking too much caffeine in coffee or sodas can make the side effects worse.
  • Check your blood pressure regularly while on Myrbetriq (mirabegron).
Learn more
More about DantriumSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Dantrium (dantrolene)?
Worth itNot sureNot worth it
More about MyrbetriqSide effectsAlternativesFDA package insert
Have you used Myrbetriq (mirabegron)?
Worth itNot sureNot worth it