Compare Dantrium vs. Sanctura

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dantrium
(dantrolene)

Sanctura
(trospium)

Relaxes your muscles. Dantrium (dantrolene) effectively treats malignant hyperthermia (increased temperature and muscle contractions when receiving anesthesia) and is the only medicine used to treat the condition. Dantrium (dantrolene) is not a first-choice treatment for general muscle spasms because it can damage your liver.Coming soon.
Reviews & ratings
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Have you used Dantrium (dantrolene)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Sanctura (trospium)?
Worth itNot sureNot worth it
Side effects
DantriumSanctura

The Dantrium FDA package insert doesn’t have numbers about how common side effects are.

More about Dantrium side effects »

We haven’t found good data for Sanctura side effects.

FDA side effect reports for Sanctura »
How it works
DantriumSanctura
Dantrium (dantrolene) stops spasms and relaxes muscle cells by interfering with the release of calcium inside muscle cells.Coming soon.
Type of medication
DantriumSanctura
Prescription only
Available as
DantriumSanctura
  • Pill
  • Injection
  • Pill
  • Extended release
Used for
DantriumSanctura
  • Malignant Hyperthermia
  • Bladder Muscle Dysfunction Overactive
Risk factors for serious side effects
DantriumSanctura
  • Taking 800 mg or more Dantrium (dantrolene) per day
  • Women
  • Over 35 years old
  • Elderly
  • History of liver disease or dysfunction
Detailed Dantrium (dantrolene) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Sleep
    DantriumSanctura
    • Taking Dantrium (dantrolene) may make you feel dizzy or sleepy for the first few days, especially if you drink alcohol or take recreational drugs. Avoid driving or other activities requiring concentration until you know how your body responds to the medication. Your body should adjust to the medicine. Talk to your doctor or pharmacist if these symptoms bother you.
    • Dantrium (dantrolene) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
    No sleep related info.
    Upsides and benefits
    DantriumSanctura
    • Dantrium (dantrolene) effectively treats malignant hyperthermia.
    • Can be used for muscle spasticity if other medications haven't worked.
    • Available as generic.
    Coming soon
    Downsides and risks
    DantriumSanctura
    • Not a first-choice treatment for muscle spasms because it can cause liver damage.
    • Can cause dizziness, sleepiness, and sometimes severe diarrhea.
    • Needs routine blood tests since it can injure your liver.
    • Dose needs to be increased slowly to minimize side effects.
    Coming soon
    Tips from our pharmacists for people taking the medication
    DantriumSanctura
    • Dantrium (dantrolene) can worsen liver function.You may need to have your blood checked regularly before starting Dantrium (dantrolene) and while you're on it.
    • Dantrium (dantrolene) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
    • Dantrium (dantrolene) can cause diarrhea, but it usually goes away within the first few weeks. If it doesn't, talk to your doctor.
    • May make your skin sensitive to the sun. Wear sunblock and avoid prolonged exposure to sunlight while on Dantrium (dantrolene).
    Coming soon
    Learn more
    More about DantriumSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Dantrium (dantrolene)?
    Worth itNot sureNot worth it
    More about SancturaSide effectsFDA package insert
    Have you used Sanctura (trospium)?
    Worth itNot sureNot worth it