Compare Dantrium vs. Vesicare

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dantrium (dantrolene)

Prescription only

Vesicare (solifenacin)

Prescription only
Relaxes your muscles.

Dantrium (dantrolene) effectively treats malignant hyperthermia (increased temperature and muscle contractions when receiving anesthesia) and is the only medicine used to treat the condition. Dantrium (dantrolene) is not a first-choice treatment for general muscle spasms because it can damage your liver.

Treats overactive bladder.

Vesicare (solifenacin) is a good choice for treatment of overactive bladder if exercises and other behavioral methods haven't worked.

Upsides
  • Dantrium (dantrolene) effectively treats malignant hyperthermia.
  • Can be used for muscle spasticity if other medications haven't worked.
  • Available as generic.
  • Vesicare (solifenacin) helps you to urinate less often.
  • Its once daily dosing is more convenient than other medicines that work like it.
Downsides
  • Not a first-choice treatment for muscle spasms because it can cause liver damage.
  • Can cause dizziness, sleepiness, and sometimes severe diarrhea.
  • Needs routine blood tests since it can injure your liver.
  • Dose needs to be increased slowly to minimize side effects.
  • Can cause drowsiness and increase the risk of falls, especially in the elderly.
  • Not a good option if you have untreated, narrow-angle glaucoma.
Used for
  • Malignant hyperthermia
  • Chronic spasticity
Dosage forms
  • Pill
  • Injection
  • Pill
Price
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Reviews
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Side effects
The Dantrium (dantrolene) FDA package insert doesn’t have numbers about how common side effects are.
8possible side effects
  • Dry mouth
    11%
  • Constipation
    5%
  • Blurry vision
    4%
  • Urinary tract infection
    3%
  • Nausea
    2%
  • Upper abdominal pain
    2%
  • Flu
    2%
  • Dizziness
    2%
See more detailed side effects
Risks and risk factors
  • Liver injury
    • Taking 800 mg or more Dantrium (dantrolene) per day
    • Women
    • Over 35 years old
    • Elderly
    • History of liver disease or dysfunction
  • Drowsiness and dizziness
    • Alcohol or recreational drug use
  • Sun sensitivity
  • Lung disease
    • COPD
    • Heart failure
See more detailed risks and warnings
  • Tissue swelling
  • Drowsiness
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • People age 65 or older
  • Vision changes
    • Glaucoma
  • Urinary blockage
    • Bladder outflow obstruction
  • Worsening side effects
    • History of kidney problems
    • People age 65 or older
  • Temperature dysregulation
    • Outside in hot weather
    • Dehydrated
    • Exercising
    • Added people 65 and older per Beer's Criteria
    • People age 65 and older
See more detailed risks and warnings