Compare Dayquil Cold And Flu vs. Mucinex DM

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relieves cold and flu symptoms.

Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan) is a useful combination medicine that relieves cold and flu symptoms, but make sure you really need all of its ingredients.

3.7/ 5 average rating with 1034 reviewsforDayquil Cold And Flu
Breaks up mucus and relieves cough.

Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.

3.9/ 5 average rating with 15 reviewsforMucinex DM
Upsides
  • Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
  • Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
  • The extended release version of Mucinex DM lasts up to 12 hours.
Downsides
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.
  • Can cause sleepiness, dizziness, and an upset stomach.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Extended release
  • Liquid
No pricing information available
No pricing information available
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Reviews
1034 reviews so far
81%
saidit'sworth it
38%
saiditworked well
5%
saidit'sa big hassle

Have you used Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan)?

Leave a review
15 reviews so far
73%
saidit'sworth it
73%
saiditworked well
13%
saidit'sa big hassle

Have you used Mucinex Dm (Dextromethorphan / Guaifenesin)?

Leave a review
Side effects
The Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan) FDA package insert doesn’t have numbers about how common side effects are.
The Mucinex Dm (Dextromethorphan / Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Liver damage
    • Drinking more than 2 alcoholic beverages a day
    • Taking with other Tylenol-containing medicines
    • History of liver disease
  • High blood pressure
    • History of high blood pressure
    • Taking MAO inhibitors
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Harm to fetus
    • Women of childbearing age
  • Chronic cough
    • History of chronic obstructive pulmonary disease (COPD)
    • History of smoking
See more detailed risks and warnings
  • Nausea and vomiting
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Cough warning
See more detailed risks and warnings