Compare Dayquil Cold And Flu vs. Robitussin DM

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dayquil Cold And Flu
(acetaminophen / phenylephrine / dextromethorphan)

Robitussin Dm
(guaifenesin / dextromethorphan)

Relieves cold and flu symptoms. Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan) is a useful combination medicine that relieves cold and flu symptoms, but make sure you really need all of its ingredients.Breaks up mucus and relieves cough. Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.09Dayquil Cold And Flu
Reviews for Dayquil Cold And Flu
81%
of people (All ages) say Dayquil Cold And Flu is worth it
38%
say it works well
5%
say it's a big hassle
1034 reviews
Have you used Dayquil Cold And Flu (acetaminophen / phenylephrine / dextromethorphan)?
Worth itNot sureNot worth it
Reviews for Robitussin DM
75%
+6% better vs. Dayquil Cold And Flu
37%
+1% better vs. Dayquil Cold And Flu
7%
+2% better vs. Dayquil Cold And Flu
724 reviews
Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
Worth itNot sureNot worth it
Side effects
Dayquil Cold And FluRobitussin DM

We haven’t found good data for Dayquil Cold And Flu side effects.

FDA side effect reports for Dayquil Cold And Flu »

We haven’t found good data for Robitussin DM side effects.

FDA side effect reports for Robitussin DM »
How it works
Dayquil Cold And FluRobitussin DM
Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan) is a combination medicine that treats cold and flu symptoms. Acetaminophen relieves pain and reduces fever. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.
Type of medication
Dayquil Cold And FluRobitussin DM
Over-the-counterOver-the-counter
Available as
Dayquil Cold And FluRobitussin DM
  • Pill
  • Liquid
  • Liquid
Used for
Dayquil Cold And FluRobitussin DM
Risk factors for serious side effects
Dayquil Cold And FluRobitussin DM
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other Tylenol-containing medicines
  • History of liver disease
  • History of high blood pressure
  • Taking MAO inhibitors
Detailed Dayquil Cold And Flu (acetaminophen / phenylephrine / dextromethorphan) risks & warnings »
  • Using other medications that affect serotonin
Detailed Robitussin Dm (guaifenesin / dextromethorphan) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Kidneys and liver
Dayquil Cold And FluRobitussin DM
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
No kidneys and liver related info.
Pain
Dayquil Cold And FluRobitussin DM
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
No pain related info.
Upsides and benefits
Dayquil Cold And FluRobitussin DM
  • Dayquil Cold And Flu (Acetaminophen / Phenylephrine / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
  • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
Downsides and risks
Dayquil Cold And FluRobitussin DM
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
  • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
  • Can cause sleepiness, dizziness, and an upset stomach.
Tips from our pharmacists for people taking the medication
Dayquil Cold And FluRobitussin DM
  • Phenylephrine, the decongestant, can make you restless, so don't take it too close to bedtime.
  • If you get the liquid form, use the dosing cup to measure the exact amount of medicine you need.
  • Follow age-specific dosing instructions on how much to take.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Let your doctor know if your symptoms don't improve in a few days, or if you have a really bad sore throat with a fever, headache, nausea, or vomiting.
  • Drink plenty of fluids while taking Robitussin Dm (Guaifenesin / Dextromethorphan) because liquid helps break down mucus.
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • If your cough lasts more than 7 days, call your doctor.
Learn more
More about Dayquil Cold And FluSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Dayquil Cold And Flu (acetaminophen / phenylephrine / dextromethorphan)?
Worth itNot sureNot worth it
More about Robitussin DMSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
Worth itNot sureNot worth it