Compare Delsym vs. Advil Cold and Sinus

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Delsym
(Dextromethorphan)

Advil Cold And Sinus
(Ibuprofen / Pseudoephedrine)

Relieves coughing. Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.Relieves sinus pain and congestion. Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.487394957983193Delsym
Reviews for Delsym (Dextromethorphan)
64%
of people say Delsym (Dextromethorphan) is worth it
31%
say it works well
12%
say it's a big hassle
Reviews for Advil Cold And Sinus (Ibuprofen / Pseudoephedrine)
75%
+11% vs. Delsym (Dextromethorphan)
34%
+3% vs. Delsym (Dextromethorphan)
6%
+6% vs. Delsym (Dextromethorphan)
Side effects
DelsymAdvil Cold and Sinus

We haven’t found good data for Delsym side effects.

FDA side effect reports for Delsym »

We haven’t found good data for Advil Cold and Sinus side effects.

FDA side effect reports for Advil Cold and Sinus »
How it works
DelsymAdvil Cold and Sinus
Delsym (Dextromethorphan) is a cough suppressant.Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) is a combination medicine that relieves cold symptoms and sinus pressure. Ibuprofen (an NSAID) relieves pain and reduces fever. Pseudoephedrine (a decongestant) clears your sinuses.
Type of medication
DelsymAdvil Cold and Sinus
Cough suppressantOver-the-counter
Pain reliever
NSAID
DecongestantOver-the-counter
Available as
DelsymAdvil Cold and Sinus
  • Pill
  • Liquid extended release
  • Pill
Used for (click to learn more)
DelsymAdvil Cold and Sinus
Risk factors for serious side effects
DelsymAdvil Cold and Sinus
  • Using other medications that affect serotonin
Detailed Delsym (Dextromethorphan) risks & warnings »
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Women of childbearing age
  • History of high blood pressure
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • History of heart problems
  • Age 65 years or older
  • Taking with aspirin
Detailed Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) risks & warnings »
Pregnancy category
DelsymAdvil Cold and Sinus
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.
  • Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) contains ibuprofen, an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) for any amount of time.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
DelsymAdvil Cold and Sinus
  • Good for treating dry cough.
  • Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
  • Available as a liquid and a tablet.
  • Some products relieve cough for up to 12 hours.
  • Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) is a combination medicine that relieves cold symptoms. It's good to use if you have congestion, sore throat, headache, or fever.
  • Ibuprofen (a pain reliever) is more effective than acetaminophen at lowering fever and relieving sinus pain.
  • Pseudoephedrine (a decongestant) clears nose congestion to help you breathe better.
Downsides and risks
DelsymAdvil Cold and Sinus
  • Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
  • If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
  • If you don't need both of the medications in this combination, you'd be taking extra medicine and can have extra side effects for no reason.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
  • Pseudoephedrine, the decongestant in Advil Cold And Sinus (Ibuprofen / Pseudoephedrine), can make your heart race or make you feel anxious and restless.
Tips from our pharmacists for people taking the medication
DelsymAdvil Cold and Sinus
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • If your cough lasts more than 7 days, call your doctor.
  • Starts working in 30 minutes.
  • You need to show an ID to buy Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
  • Don't take it if you have an allergy to aspirin since ibuprofen can cause a similar reaction.
  • Take it after eating to avoid getting an upset stomach.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • Be careful taking Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) if you have a history of bleeding problems or ulcers since it can make them worse.
  • Talk to your doctor if symptoms don't get better in 1 week.
Learn more
More about DelsymSide effectsReviews & ratingsAlternativesFDA package insert
More about Advil Cold and SinusSide effectsReviews & ratingsAlternativesFDA package insert